Review
Clinical Neurology
Steven M. Falowski, Vipul Mangal, Jason Pope, Anish Patel, Mark Coleman, Dan Kendall, Richard Brouillette, Michael A. Fishman
Summary: This retrospective analysis evaluated the use of ISF for patients with lumbar degenerative disc disease and spinal stenosis. The results showed a 0% adverse event rate, significant pain reduction, and successful outcomes, indicating the safety and efficacy of ISF performed by interventional pain physicians.
JOURNAL OF PAIN RESEARCH
(2021)
Review
Medicine, Research & Experimental
Alan D. Kaye, Amber N. Edinoff, Shavonne N. Temple, Aaron J. Kaye, Azem A. Chami, Rutvij J. Shah, Bruce M. Dixon, Michael A. Alvarado, Elyse M. Cornett, Omar Viswanath, Ivan Urits, Aaron K. Calodney
Summary: Spinal stenosis is the narrowing of the spinal canal, causing compression of nerve roots. Treatment options include implants and surgical interventions, with newer procedures showing promise in safety and efficacy.
ADVANCES IN THERAPY
(2021)
Article
Medicine, Research & Experimental
Peter G. Whang, Oth Tran, Howard L. Rosner
Summary: This study compared the postoperative outcomes and rates of subsequent interventions between lumbar spinal stenosis (LSS) patients treated with an interspinous spacer device (ISD) and those with open decompression or fusion. The results showed that compared to ISD patients, those who received open surgery were more likely to require subsequent fusion or other lumbar spine surgeries, and were also more likely to experience short-term life-threatening events and long-term complications. Additionally, ISD patients had lower costs.
ADVANCES IN THERAPY
(2023)
Article
Clinical Neurology
Sunao Tanaka, Kanichiro Wada, Gentaro Kumagai, Toru Asari, Shuichi Aburakawa, Yoshihito Yamasaki, Toru Yokoyama, Kazunari Takeuchi, Yasuyuki Ishibashi
Summary: A multi-center, retrospective study was conducted to clarify the effects of removing interspinous contextures in lumbar decompression surgery for patients with lumbar spinal stenosis. The study found that the removal of interspinous contextures did not significantly impact clinical outcomes one year post-surgery, but may cause disc height loss at the L4/5 level.
Review
Clinical Neurology
Hongjie Yuan, Xiaobin Yi
Summary: This narrative review aims to clarify the efficacy, safety profile, certain procedure details, advantages, and limitations of MILD for LSS. According to the literature, MILD is an effective and safe procedure that can significantly reduce pain intensity and improve functional status in LSS patients.
JOURNAL OF PAIN RESEARCH
(2023)
Article
Clinical Neurology
Yuto Kobayashi, Koji Tamai, Hiromitsu Toyoda, Hidetomi Terai, Masatoshi Hoshino, Akinobu Suzuki, Shinji Takahashi, Yusuke Hori, Akito Yabu, Hiroaki Nakamura
Summary: Results from a study involving 198 patients with LSS indicate that there was no significant difference in clinical outcomes 5 years after minimally invasive posterior decompression between patients with degenerative spondylolisthesis (DS) and those without DS. Additionally, after carefully excluding patients with segmental instability, DS did not impact the clinical outcomes of minimally invasive decompression surgery.
Article
Clinical Neurology
Patawut Bovonratwet, Andre M. Samuel, Jung Kee Mok, Avani S. Vaishnav, Kyle W. Morse, Junho Song, Michael E. Steinhaus, Yusef J. Jordan, Catherine H. Gang, Sheeraz A. Qureshi
Summary: This study compared the outcomes of minimally invasive unilateral laminotomy with bilateral decompression (MIS-ULBD) and minimally invasive transforaminal lumbar interbody fusion (MIS-TLIF) for the treatment of low-grade lumbar degenerative spondylolisthesis. The results showed that both procedures resulted in significant improvements in pain and physical function for the patients.
Article
Medicine, General & Internal
Quan-You Gao, Fei-Long Wei, Tian Li, Kai-Long Zhu, Ming-Rui Du, Wei Heng, Fan Yang, Hao-Ran Gao, Ji-Xian Qian, Cheng-Pei Zhou
Summary: This study compared the outcomes and complications of patients with lumbar spinal stenosis (LSS) undergoing oblique lateral interbody fusion (OLIF) or minimally invasive transforaminal lumbar interbody fusion (MIS-TLIF). The results showed that OLIF and MIS-TLIF had similar postoperative improvements, but OLIF was more successful at restoring disc height, foraminal height, and lumbar lordotic angle. The complication rates were comparable between the two procedures.
FRONTIERS IN MEDICINE
(2022)
Review
Pharmacology & Pharmacy
Y-X Hu, Y-F Wang, J. Han, S-M Liu, H. Wang
Summary: With the advancement of minimally invasive techniques, percutaneously placed interspinous stabilization devices have been gradually recognized by doctors and patients as the future direction in this field. This paper reviews the current clinical research progress in this area and emphasizes the importance of conducting more clinical studies with long-term follow-up.
EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES
(2022)
Article
Surgery
Lu Lin, Xiao-Qin Liu, Lei Shi, Si Cheng, Zhi-Qiang Wang, Qi-Jun Ge, Ding-Zhi Gao, Amadou Cheffou Ismail, Zhen-Yong Ke, Lei Chu
Summary: This study compared postoperative outcomes and patient-reported outcomes (PROs) between percutaneous endoscopic lumbar interbody fusion (PE-LIF) and minimally invasive transforaminal lumbar interbody fusion (MIS-TLIF) for treating lumbar spinal stenosis (LSS). The results showed that both PE-LIF and MIS-TLIF were safe and effective for LSS, but PE-LIF had a shorter operative time and less trauma, resulting in better short-term outcomes.
FRONTIERS IN SURGERY
(2022)
Article
Clinical Neurology
Min-Seok Kang, Ki-Han You, Jun-Young Choi, Dong-Hwa Heo, Hoon-Jae Chung, Hyun-Jin Park
Summary: The study aimed to compare the clinical and radiological outcomes of BE-TLIF and MT-TLIF in patients with single- or two-segment lumbar spinal stenosis. The results showed that both surgical techniques provided equivalent and favorable clinical outcomes and fusion rates.
Article
Health Care Sciences & Services
Kai-Uwe Lewandrowski, Anthony P. Yeung, Morgan Lorio, Huilin Yang, Jorge Felipe Ramirez Leon, Jose Antonio Soriano Sanchez, Rossano Kepler Alvim Fiorelli, Kang Taek Lim, Jaime Moyano, Alvaro Dowling, Juan Marcelo Sea Aramayo, Jeong-Yoon Park, Hyeun-Sung Kim, Jiancheng Zeng, Bin Meng, Fernando Alvarado Gomez, Carolina Ramirez, Paulo Sergio Teixeira De Carvalho, Manuel Rodriguez Garcia, Alfonso Garcia, Eulalio Elizalde Martinez, Iliana Margarita Gomez Silva, Jose Edgardo Valerio Pascua, Luis Miguel Duchen Rodriguez, Robert M. Meves, Cristiano Menezes, Luis Eduardo Carelli, Alexandre Fogaca Cristante, Rodrigo Amaral, Geraldo de Sa Carneiro, Helton Defino, Vicky Yamamoto, Babak Kateb
Summary: Pain generator-based lumbar spinal decompression surgery is considered durable and cost-effective in treating degenerative lumbar spine conditions. Simplified decompression procedures targeting validated pain generators have lower perioperative complications and revision rates. This perspective article summarizes successful management techniques for spinal stenosis patients using transforaminal endoscopic and translaminar minimally invasive spinal surgery, with the consensus of multiple international surgeon societies based on thorough literature review.
JOURNAL OF PERSONALIZED MEDICINE
(2023)
Article
Orthopedics
Bin Yu, Jin Zhang, Jie Pan, Yizhou Wang, YingGao Chen, Weidong Zhao, Desheng Wu
Summary: The study found that patients undergoing Mis-TLIF for lumbar spinal stenosis experienced less anxiety and better clinical outcomes compared to those undergoing open TLIF. Anxiety levels in Mis-TLIF patients were positively correlated with postoperative VAS and ODI scores.
ORTHOPAEDIC SURGERY
(2021)
Article
Anesthesiology
Howard L. Rosner, Oth Tran, Tina Vajdi, Mary A. Vijjeswarapu
Summary: This study examined the safety outcomes and rates of subsequent spinal procedures between patients with degenerative lumbar spinal stenosis (LSS) receiving an interspinous spacer without decompression or fusion (ISD) versus minimally invasive lumbar decompression (MILD) as the first surgical intervention. The results showed that ISD and MILD have equivalent safety profiles, but ISD has lower rates of open decompression and MILD.
REGIONAL ANESTHESIA AND PAIN MEDICINE
(2023)
Article
Clinical Neurology
Luca Jacopo Pavan, Danoob Dalili, Aldo Eros De Vivo, Arthur Hamel-Senecal, Federico Torre, Alexandre Rudel, Luigi Manfre, Nicolas Amoretti
Summary: The study evaluated the clinical and radiological outcomes of patients with lumbar spinal stenosis treated with a removable percutaneous interspinous process spacer device, demonstrating significant pain reduction, functional improvement, and increased neural foramina area at 3-month follow-up with favorable safety profile.
Article
Peripheral Vascular Disease
Saravanan Balamuthusamy, Larry E. Miller, Diana Clynes, Erin Kahle, Richard A. Knight, Paul T. Conway
JOURNAL OF VASCULAR ACCESS
(2020)
Review
Orthopedics
Larry E. Miller, Samir Bhattacharyya, William R. Parrish, Michael Fredericson, Brad Bisson, Roy D. Altman
Summary: This systematic review and meta-analysis found that intra-articular hyaluronic acid (IAHA) is safe for use in patients with symptomatic knee osteoarthritis. When compared with intra-articular saline, IAHA was associated with a higher risk of nonserious, transient local reactions, but there was no indication of any additional safety risks.
Letter
Urology & Nephrology
Larry E. Miller, Bilal Chughtai, Ryan A. Dornbier, Kevin T. McVary
JOURNAL OF UROLOGY
(2021)
Review
Urology & Nephrology
Naeem Bhojani, Larry E. Miller, Samir Bhattacharyya, Ben Cutone, Ben H. Chew
Summary: Urosepsis is a serious potential complication of ureteroscopic procedures for stone disease, and this systematic review with meta-analysis identified potential risk factors for postoperative urosepsis. Among patients undergoing URS for treatment of stone disease, older age, diabetes mellitus, ischemic heart disease, preoperative stent placement, positive urine culture, and longer procedure time were associated with increased risk of urosepsis.
JOURNAL OF ENDOUROLOGY
(2021)
Review
Engineering, Biomedical
Maddalena Giannella, George A. Pankey, Renato Pascale, Valerie M. Miller, Larry E. Miller, Tamara Seitz
Summary: T2 Magnetic Resonance (T2MR) provides faster detection time, quicker transition to targeted therapy, speedier de-escalation of treatment, shorter ICU and hospital stay for suspected bloodstream infection patients compared to traditional blood culture (BC), with comparable mortality rates.
EXPERT REVIEW OF MEDICAL DEVICES
(2021)
Review
Medicine, General & Internal
Heather A. Payne, Michael Pinkawa, Clive Peedell, Samir K. Bhattacharyya, Emily Woodward, Larry E. Miller
Summary: This study evaluated the clinical utility of the hydrogel rectal spacer in men receiving SBRT for prostate cancer. Results showed that the rectal spacer effectively reduced rectal radiation exposure and had a positive impact on GI toxicity.
Article
Medicine, General & Internal
Claudius Thome, Adisa Kursumovic, Peter Douglas Klassen, Gerrit J. Bouma, Richard Bostelmann, Frederic Martens, Martin Barth, Mark Arts, Larry E. Miller, Peter Vajkoczy, Robert Hes, Sandro Eustacchio, Dharmin Nanda, Hans-Peter Koehler, Christopher Brenke, Charlotte Flueh, Erik Van de Kelft, Richard Assaker, Jenny C. Kienzler, Javier Fandino
Summary: Patients with large annular defects following lumbar microdiscectomy are at high risk of symptomatic recurrence and reoperation. Adding a bone-anchored annular closure device to the procedure significantly reduces the risk of reherniation and reoperation over a 5-year follow-up period.
Review
Urology & Nephrology
Larry E. Miller, Mohit Khera, Samir Bhattacharyya, Mital Patel, Krista Nitschelm, Arthur L. Burnett
Summary: The purpose of this study was to determine the long-term survival rate of inflatable penile prostheses (PP) and identify potential factors that may affect device survival. Through a systematic review and meta-analysis, it was found that the survival rates of durable inflatable penile prostheses at 1, 3, 5, 10, 15, and 20 years were 93.3%, 91.0%, 87.2%, 76.8%, 63.7%, and 52.9% respectively. Newer studies had better device survival rates, but the factors responsible for the improvement remain unclear and require further research.
Review
Urology & Nephrology
Mohit Khera, Samir Bhattacharyya, Larry E. Miller
Summary: Regular aerobic exercise can improve erectile function in men, particularly those with lower baseline scores on the International Index of Erectile Function (IIEF-EF).
JOURNAL OF SEXUAL MEDICINE
(2023)
Article
Medicine, General & Internal
Anna L. Miller, Mehul Bhattacharyya, Ruemon Bhattacharyya, Frederick Frankhauser, Larry E. Miller
Summary: This study investigated the social- and health-related factors associated with life dissatisfaction among adults in the US. The findings revealed that recent psychological distress, unmarried status, poor general health, lack of social/emotional support, and lower food security were independently associated with life dissatisfaction. The study also identified racial inequities in the prevalence of these factors, highlighting the need for targeted resource prioritization for racial minority groups.
Article
Medicine, General & Internal
Kyle R. Eberlin, Christopher J. Dy, Mark D. Fischer, James L. Gluck, F. Thomas D. Kaplan, Thomas J. McDonald, Larry E. Miller, Alexander Palmer, Marc E. Walker, James F. Watt
Summary: This randomized controlled trial aims to compare the safety and effectiveness of ultrasound-guided CTR with mini-open CTR in patients with symptomatic CTS. The primary endpoint is the percentage of patients who return to normal daily activities within 3 days of the procedure. The results of this trial will have important clinical and economic implications for the treatment of CTS.
Article
Medicine, General & Internal
Sirikan Rojanasarot, Benjamin Cutone, Samir Bhattacharyya, Kyle DeRouen, Larry E. Miller
Summary: The study found that in middle-aged men prescribed oral medication for LUTS secondary to BPH, the risk of BPH surgery was 10.2% over five years. Age was the primary factor associated with higher surgery risk.
CUREUS JOURNAL OF MEDICAL SCIENCE
(2022)
Article
Medicine, General & Internal
Frederick Moore, Betsy H. Grunch, Larry E. Miller, Michael J. Musacchio
Summary: Before widespread adoption of new medical devices, thorough evaluation of safety, effectiveness, and cost-utility is essential. Health technology assessment is a systematic evaluation of benefits and harms aimed at informing healthcare policy decisions and preventing adoption of devices with harmful or doubtful value.
CUREUS JOURNAL OF MEDICAL SCIENCE
(2021)
Review
Engineering, Biomedical
Kevin T. McVary, Bilal Chughtai, Larry E. Miller, Samir K. Bhattacharyya, Ryan A. Dornbier, Dean S. Elterman
Summary: LUTS caused by BPH in older men is highly prevalent, with a clinical need for safer, effective, and durable treatment options. Traditional surgical procedures for BPH have risks and side effects, leading to a growing interest in minimally invasive surgical treatments.
MEDICAL DEVICES-EVIDENCE AND RESEARCH
(2021)
Review
Orthopedics
Larry E. Miller, Michael Fredericson, Roy D. Altman
ORTHOPAEDIC JOURNAL OF SPORTS MEDICINE
(2020)