How genetic variation affects patient response and outcome to therapy for psoriasis

Molecular discrimination of responders and nonresponders to anti-TNFalpha therapy in rheumatoid arthritis by etanercept

(2012) Dirk Koczan et al.   ARTHRITIS RESEARCH & THERAPY

Ulcerative Colitis Practice Guidelines in Adults: American College of Gastroenterology, Practice Parameters Committee

(2010) Asher Kornbluth et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Investigation of rheumatoid arthritis susceptibility genes identifies association of AFF3 and CD226 variants with response to anti-tumour necrosis factor treatment

(2010) R. J. L. Tan et al.   ANNALS OF THE RHEUMATIC DISEASES

Association between anti-tumour necrosis factor treatment response and genetic variants within the TLR and NF B signalling pathways

(2010) C. Potter et al.   ANNALS OF THE RHEUMATIC DISEASES

British Association of Dermatologists guidelines on the efficacy and use of acitretin in dermatology

(2010) A.D. Ormerod et al.   BRITISH JOURNAL OF DERMATOLOGY

Effect of CYP3A and ABCB1 Single Nucleotide Polymorphisms on the Pharmacokinetics and Pharmacodynamics of Calcineurin Inhibitors: Part I

(2010) Christine E. Staatz et al.   CLINICAL PHARMACOKINETICS

Advances in treatment of chronic myelogenous leukemia – new treatment options with tyrosine kinase inhibitors

(2010) Fabio P. S. Santos et al.   LEUKEMIA & LYMPHOMA

Genome-wide association studies in pharmacogenomics

(2010) Ann K. Daly   NATURE REVIEWS GENETICS

Management of Crohn's Disease in Adults

(2009) Gary R Lichtenstein et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Apolipoprotein ε4 allele is associated with psoriasis severity

(2009) Pablo Coto-Segura et al.   ARCHIVES OF DERMATOLOGICAL RESEARCH

Outcomes of methotrexate therapy for psoriasis and relationship to genetic polymorphisms

(2009) R.B. Warren et al.   BRITISH JOURNAL OF DERMATOLOGY

British Association of Dermatologists’ guidelines for biologic interventions for psoriasis 2009

(2009) C.H. Smith et al.   BRITISH JOURNAL OF DERMATOLOGY

Advances in individual prediction of methotrexate toxicity: a review

(2009) Kjeld Schmiegelow   BRITISH JOURNAL OF HAEMATOLOGY

Individualizing Calcineurin Inhibitor Therapy in Renal Transplantation - Current Limitations and Perspectives

(2009) R. Press et al.   CURRENT PHARMACEUTICAL DESIGN

Criteria for the selection of single nucleotide polymorphisms in pathway pharmacogenetics: TNF inhibitors as a case study

(2009) Wouter M. Kooloos et al.   DRUG DISCOVERY TODAY

Patients with severe psoriasis are at increased risk of cardiovascular mortality: cohort study using the General Practice Research Database

(2009) N. N. Mehta et al.   EUROPEAN HEART JOURNAL

Pharmacogenomics in dermatology: from susceptibility genes to personalized therapy

(2009) Carlo Pincelli et al.   EXPERIMENTAL DERMATOLOGY

Effective treatment of psoriasis with etanercept is linked to suppression of IL-17 signaling, not immediate response TNF genes

(2009) Lisa C. Zaba et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

No Increased Risk of Cancer after Coal Tar Treatment in Patients with Psoriasis or Eczema

(2009) Judith H.J. Roelofzen et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Molecular Dissection of Psoriasis: Integrating Genetics and Biology

(2009) James T. Elder et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Guidelines of care for the management of psoriasis and psoriatic arthritis

(2009) Alan Menter et al.   JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY

Guidelines of care for the management of psoriasis and psoriatic arthritis

(2009) Alan Menter et al.   JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY

Behandlung der Plaque-Psoriasis mit Biologics

(2009) Zhengguang Zhang et al.   MEDIZINISCHE KLINIK

Psoriasis genome-wide association study identifies susceptibility variants within LCE gene cluster at 1q21

(2009) Xue-Jun Zhang et al.   NATURE GENETICS

Genome-wide scan reveals association of psoriasis with IL-23 and NF-κB pathways

(2009) Rajan P Nair et al.   NATURE GENETICS

Estimation of the Warfarin Dose with Clinical and Pharmacogenetic Data

(2009)   NEW ENGLAND JOURNAL OF MEDICINE

Psoriasis

(2009) Frank O. Nestle et al.   NEW ENGLAND JOURNAL OF MEDICINE

TNF-α −308 G/A polymorphism and responsiveness to TNF-α blockade therapy in moderate to severe rheumatoid arthritis: a systematic review and meta-analysis

(2009) D D O'Rielly et al.   PHARMACOGENOMICS JOURNAL

Can rheumatoid arthritis responsiveness to methotrexate and biologics be predicted?

(2009) C. Bansard et al.   RHEUMATOLOGY

Multiple Loci within the Major Histocompatibility Complex Confer Risk of Psoriasis

(2009) Bing-Jian Feng et al.   PLoS Genetics

Retinoids as Critical Modulators of Immune Functions: New Therapeutic Perspectives for Old Compounds

(2009) Michele Montrone et al.   Endocrine Metabolic & Immune Disorders-Drug Targets

Clinical impact of the methotrexate resistance-associated genes C-MYC and dihydrofolate reductase (DHFR) in high-grade osteosarcoma

(2008) I. Scionti et al.   ANNALS OF ONCOLOGY

Safety and Efficacy of ABT-874, a Fully Human Interleukin 12/23 Monoclonal Antibody, in the Treatment of Moderate to Severe Chronic Plaque Psoriasis

(2008) Alexa B. Kimball   ARCHIVES OF DERMATOLOGY

Efficacy and tolerability of biologic and nonbiologic systemic treatments for moderate-to-severe psoriasis: meta-analysis of randomized controlled trials

(2008) J. Schmitt et al.   BRITISH JOURNAL OF DERMATOLOGY

Identification of ZNF313 / RNF114 as a novel psoriasis susceptibility gene

(2008) Francesca Capon et al.   HUMAN MOLECULAR GENETICS

Genetic Variation in Efflux Transporters Influences Outcome to Methotrexate Therapy in Patients with Psoriasis

(2008) Richard B. Warren et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Efficacy and safety of ustekinumab, a human interleukin-12/23 monoclonal antibody, in patients with psoriasis: 76-week results from a randomised, double-blind, placebo-controlled trial (PHOENIX 1)

(2008) Craig L Leonardi et al.   LANCET

A Genome-Wide Association Study of Psoriasis and Psoriatic Arthritis Identifies New Disease Loci

(2008) Ying Liu et al.   PLoS Genetics