Tocilizumab: molecular intervention therapy in children with systemic juvenile idiopathic arthritis

Clinical value of blocking IL-6 receptor

(2010) Toru Mima et al.   CURRENT OPINION IN RHEUMATOLOGY

The Role of Hepcidin in Iron Metabolism

(2009) Elizabeta Nemeth et al.   ACTA HAEMATOLOGICA

Defective phosphorylation of interleukin-18 receptor β causes impaired natural killer cell function in systemic-onset juvenile idiopathic arthritis

(2009) Wilco de Jager et al.   ARTHRITIS AND RHEUMATISM

Systemic JIA: new developments in the understanding of the pathophysiology and therapy

(2009) Sebastiaan J. Vastert et al.   BEST PRACTICE & RESEARCH IN CLINICAL RHEUMATOLOGY

Interleukin-6 inhibits early differentiation of ATDC5 chondrogenic progenitor cells

(2009) Shoko Nakajima et al.   CYTOKINE

Hemophagocytic Lymphohistiocytosis: When the Immune System Runs Amok

(2009) G. Janka   KLINISCHE PADIATRIE

Mutations in the perforin gene can be linked to macrophage activation syndrome in patients with systemic onset juvenile idiopathic arthritis

(2009) Sebastiaan J. Vastert et al.   RHEUMATOLOGY

Interleukin (IL)-6 and IL-1β act synergistically within the brain to induce sickness behavior and fever in rats

(2008) Lois M. Harden et al.   BRAIN BEHAVIOR AND IMMUNITY

How the study of children with rheumatic diseases identified interferon-α and interleukin-1 as novel therapeutic targets

(2008) Virginia Pascual et al.   IMMUNOLOGICAL REVIEWS

Detailing the role of Bax translocation, cytochromecrelease, and perinuclear clustering of the mitochondria in the killing of HeLa cells by TNF

(2008) Bruna Pucci et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Efficacy and safety of tocilizumab in patients with systemic-onset juvenile idiopathic arthritis: a randomised, double-blind, placebo-controlled, withdrawal phase III trial

(2008) Shumpei Yokota et al.   LANCET

Role of Interleukin-6 in the Anemia of Chronic Disease

(2008) Dominic S.C. Raj   SEMINARS IN ARTHRITIS AND RHEUMATISM