Chemotherapy regimens in early breast cancer: major controversies and future outlook

Comparisons between different polychemotherapy regimens for early breast cancer: meta-analyses of long-term outcome among 100 000 women in 123 randomised trials

(2013)   LANCET

Dose-dense chemotherapy versus conventional chemotherapy for early breast cancer: A systematic review with meta-analysis

(2012) Igor Lemos Duarte et al.   BREAST

Dissecting the Heterogeneity of Triple-Negative Breast Cancer

(2012) Otto Metzger-Filho et al.   JOURNAL OF CLINICAL ONCOLOGY

Molecular Classification of Estrogen Receptor-positive/Luminal Breast Cancers

(2011) Felipe C. Geyer et al.   ADVANCES IN ANATOMIC PATHOLOGY

Strategies for subtypes—dealing with the diversity of breast cancer: highlights of the St Gallen International Expert Consensus on the Primary Therapy of Early Breast Cancer 2011

(2011) A. Goldhirsch et al.   ANNALS OF ONCOLOGY

Topoisomerase II alpha protein and responsiveness of breast cancer to adjuvant chemotherapy with CEF compared to CMF in the NCIC CTG randomized MA.5 adjuvant trial

(2011) F. P. O’Malley et al.   BREAST CANCER RESEARCH AND TREATMENT

A New Molecular Predictor of Distant Recurrence in ER-Positive, HER2-Negative Breast Cancer Adds Independent Information to Conventional Clinical Risk Factors

(2011) Martin Filipits et al.   CLINICAL CANCER RESEARCH

Adjuvant Chemotherapy, with or without Taxanes, in Early or Operable Breast Cancer: A Meta-Analysis of 19 Randomized Trials with 30698 Patients

(2011) Ying-Yi Qin et al.   PLoS One

Intense Dose-Dense Sequential Chemotherapy With Epirubicin, Paclitaxel, and Cyclophosphamide Compared With Conventionally Scheduled Chemotherapy in High-Risk Primary Breast Cancer: Mature Results of an AGO Phase III Study

(2010) Volker Moebus et al.   JOURNAL OF CLINICAL ONCOLOGY

Alteration of Topoisomerase II–Alpha Gene in Human Breast Cancer: Association With Responsiveness to Anthracycline-Based Chemotherapy

(2010) Michael F. Press et al.   JOURNAL OF CLINICAL ONCOLOGY

Primary breast cancer: ESMO Clinical Recommendations for diagnosis, treatment and follow-up

(2009) V. Kataja et al.   ANNALS OF ONCOLOGY

FEC versus sequential docetaxel followed by epirubicin/cyclophosphamide as adjuvant chemotherapy in women with axillary node-positive early breast cancer: a randomized study of the Hellenic Oncology Research Group (HORG)

(2009) Aristides Polyzos et al.   BREAST CANCER RESEARCH AND TREATMENT

A randomised pilot Phase II study of doxorubicin and cyclophosphamide (AC) or epirubicin and cyclophosphamide (EC) given 2 weekly with pegfilgrastim (accelerated) vs 3 weekly (standard) for women with early breast cancer

(2009) R L Jones et al.   BRITISH JOURNAL OF CANCER

Role of Anthracyclines in the Treatment of Early Breast Cancer

(2009) Luca Gianni et al.   JOURNAL OF CLINICAL ONCOLOGY

Docetaxel With Cyclophosphamide Is Associated With an Overall Survival Benefit Compared With Doxorubicin and Cyclophosphamide: 7-Year Follow-Up of US Oncology Research Trial 9735

(2009) Stephen Jones et al.   JOURNAL OF CLINICAL ONCOLOGY

Cyclophosphamide, Epirubicin, and Fluorouracil Versus Dose-Dense Epirubicin and Cyclophosphamide Followed by Paclitaxel Versus Doxorubicin and Cyclophosphamide Followed by Paclitaxel in Node-Positive or High-Risk Node-Negative Breast Cancer

(2009) Margot Burnell et al.   JOURNAL OF CLINICAL ONCOLOGY

Ki67 Index, HER2 Status, and Prognosis of Patients With Luminal B Breast Cancer

(2009) Maggie C. U. Cheang et al.   JNCI-Journal of the National Cancer Institute

Adjuvant chemotherapy and timing of tamoxifen in postmenopausal patients with endocrine-responsive, node-positive breast cancer: a phase 3, open-label, randomised controlled trial

(2009) Kathy S Albain et al.   LANCET

Gene-Expression Signatures in Breast Cancer

(2009) Christos Sotiriou et al.   NEW ENGLAND JOURNAL OF MEDICINE

Letrozole Therapy Alone or in Sequence with Tamoxifen in Women with Breast Cancer

(2009)   NEW ENGLAND JOURNAL OF MEDICINE

Premenopausal endocrine-responsive early breast cancer: who receives chemotherapy?

(2008) M. M. Regan et al.   ANNALS OF ONCOLOGY

A comparative study of survival models for breast cancer prognostication based on microarray data: does a single gene beat them all?

(2008) B. Haibe-Kains et al.   BIOINFORMATICS

Is chemotherapy necessary for premenopausal women with lower-risk node-positive, endocrine responsive breast cancer? 10-year update of International Breast Cancer Study Group Trial 11-93

(2008) Beat Thürlimann et al.   BREAST CANCER RESEARCH AND TREATMENT

Is adjuvant chemotherapy of benefit for postmenopausal women who receive endocrine treatment for highly endocrine-responsive, node-positive breast cancer? International Breast Cancer Study Group Trials VII and 12–93

(2008) Olivia Pagani et al.   BREAST CANCER RESEARCH AND TREATMENT

Increasing steroid hormone receptors expression defines breast cancer subtypes non responsive to preoperative chemotherapy

(2008) Marco Colleoni et al.   BREAST CANCER RESEARCH AND TREATMENT

Clinical Application of the 70-Gene Profile: The MINDACT Trial

(2008) Fatima Cardoso et al.   JOURNAL OF CLINICAL ONCOLOGY

Concurrent Doxorubicin Plus Docetaxel Is Not More Effective Than Concurrent Doxorubicin Plus Cyclophosphamide in Operable Breast Cancer With 0 to 3 Positive Axillary Nodes: North American Breast Cancer Intergroup Trial E 2197

(2008) Lori J. Goldstein et al.   JOURNAL OF CLINICAL ONCOLOGY

Adjuvant Chemotherapy With Sequential or Concurrent Anthracycline and Docetaxel: Breast International Group 02 98 Randomized Trial

(2008) P. Francis et al.   JNCI-Journal of the National Cancer Institute

Randomized Phase 3 Trial of Fluorouracil, Epirubicin, and Cyclophosphamide Alone or Followed by Paclitaxel for Early Breast Cancer

(2008) M. Martin et al.   JNCI-Journal of the National Cancer Institute

Weekly Paclitaxel in the Adjuvant Treatment of Breast Cancer

(2008) Joseph A. Sparano et al.   NEW ENGLAND JOURNAL OF MEDICINE

Taxane-Based Combinations As Adjuvant Chemotherapy of Early Breast Cancer: A Meta-Analysis of Randomized Trials

(2007) Michele De Laurentiis et al.   JOURNAL OF CLINICAL ONCOLOGY

HER2 Status and Efficacy of Adjuvant Anthracyclines in Early Breast Cancer: A Pooled Analysis of Randomized Trials

(2007) Alessandra Gennari et al.   JNCI-Journal of the National Cancer Institute