Cracking the Toll-like receptor code in fungal infections

Prospective Surveillance for Invasive Fungal Infections in Hematopoietic Stem Cell Transplant Recipients, 2001–2006: Overview of the Transplant‐Associated Infection Surveillance Network (TRANSNET) Database

(2010) Dimitrios P. Kontoyiannis et al.   CLINICAL INFECTIOUS DISEASES

Invasive Fungal Infections among Organ Transplant Recipients: Results of the Transplant‐Associated Infection Surveillance Network (TRANSNET)

(2010) Peter G. Pappas et al.   CLINICAL INFECTIOUS DISEASES

Differential IL-17 Production and Mannan Recognition Contribute to Fungal Pathogenicity and Commensalism

(2010) L. Rizzetto et al.   JOURNAL OF IMMUNOLOGY

IL-22 defines a novel immune pathway of antifungal resistance

(2010) A De Luca et al.   Mucosal Immunology

Aspergillus fumigatus Stimulates the NLRP3 Inflammasome through a Pathway Requiring ROS Production and the Syk Tyrosine Kinase

(2010) Najwane Saïd-Sadier et al.   PLoS One

Polymorphism in a gene coding for the inflammasome component NALP3 and recurrent vulvovaginal candidiasis in women with vulvar vestibulitis syndrome

(2009) Ahinoam Lev-Sagie et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Robust Th1 and Th17 Immunity Supports Pulmonary Clearance but Cannot Prevent Systemic Dissemination of Highly Virulent Cryptococcus neoformans H99

(2009) Yanmei Zhang et al.   AMERICAN JOURNAL OF PATHOLOGY

IL-17 and Th17 Cells

(2009) Thomas Korn et al.   Annual Review of Immunology

V 1 T lymphocytes producing IFN-  and IL-17 are expanded in HIV-1-infected patients and respond to Candida albicans

(2009) D. Fenoglio et al.   BLOOD

The Macrophage Mannose Receptor Induces IL-17 in Response to Candida albicans

(2009) Frank L. van de Veerdonk et al.   Cell Host & Microbe

An Essential Role for the NLRP3 Inflammasome in Host Defense against the Human Fungal Pathogen Candida albicans

(2009) Amy G. Hise et al.   Cell Host & Microbe

Signalling through TLR2/MyD88 induces differentiation of murine bone marrow stem and progenitor cells to functional phagocytes in response toCandida albicans

(2009) Alberto Yáñez et al.   CELLULAR MICROBIOLOGY

Early Stop Polymorphism in Human DECTIN‐1 Is Associated with IncreasedCandidaColonization in Hematopoietic Stem Cell Transplant Recipients

(2009) Theo S. Plantinga et al.   CLINICAL INFECTIOUS DISEASES

Fungal adaptation to the host environment

(2009) Bernhard Hube   CURRENT OPINION IN MICROBIOLOGY

IL-17/Th17 in anti-fungal immunity: What's new?

(2009) Teresa Zelante et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Polymorphisms in Toll-like receptor genes and susceptibility to infections in allogeneic stem cell transplantation

(2009) Agostinho Carvalho et al.   EXPERIMENTAL HEMATOLOGY

Plasticity of CD4+ T Cell Lineage Differentiation

(2009) Liang Zhou et al.   IMMUNITY

Anti-Aspergillushuman host defence relies on type 1 T helper (Th1), rather than type 17 T helper (Th17), cellular immunity

(2009) Louis Y. A. Chai et al.   IMMUNOLOGY

Modulation of Toll-Like Receptor 2 (TLR2) and TLR4 Responses by Aspergillus fumigatus

(2009) L. Y. A. Chai et al.   INFECTION AND IMMUNITY

Toll-Like Receptor 4 Signaling Leads to Severe Fungal Infection Associated with Enhanced Proinflammatory Immunity and Impaired Expansion of Regulatory T Cells

(2009) F. V. Loures et al.   INFECTION AND IMMUNITY

Elucidating the Pathogenesis of Spores from the Human Fungal Pathogen Cryptococcus neoformans

(2009) S. S. Giles et al.   INFECTION AND IMMUNITY

Toll-Like Receptor 9-Dependent Activation of Myeloid Dendritic Cells by Deoxynucleic Acids from Candida albicans

(2009) A. Miyazato et al.   INFECTION AND IMMUNITY

Genetic variability of innate immunity impacts human susceptibility to fungal diseases

(2009) Agostinho Carvalho et al.   INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES

Dectin-1 is Inducible and Plays an Essential Role for Mycobacteria-Induced Innate Immune Responses in Airway Epithelial Cells

(2009) Hye-Mi Lee et al.   JOURNAL OF CLINICAL IMMUNOLOGY

Th17 cells and IL-17 receptor signaling are essential for mucosal host defense against oral candidiasis

(2009) Heather R. Conti et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Cutting Edge: NF- B Activating Pattern Recognition and Cytokine Receptors License NLRP3 Inflammasome Activation by Regulating NLRP3 Expression

(2009) F. G. Bauernfeind et al.   JOURNAL OF IMMUNOLOGY

TLR2 Is a Negative Regulator of Th17 Cells and Tissue Pathology in a Pulmonary Model of Fungal Infection

(2009) F. V. Loures et al.   JOURNAL OF IMMUNOLOGY

Involvement of the NLRP3 Inflammasome in Innate and Humoral Adaptive Immune Responses to Fungal  -Glucan

(2009) H. Kumar et al.   JOURNAL OF IMMUNOLOGY

Requisite Role for the Dectin-1  -Glucan Receptor in Pulmonary Defense against Aspergillus fumigatus

(2009) J. L. Werner et al.   JOURNAL OF IMMUNOLOGY

Early NK Cell-Derived IFN-  Is Essential to Host Defense in Neutropenic Invasive Aspergillosis

(2009) S. J. Park et al.   JOURNAL OF IMMUNOLOGY

Immune Sensing of Aspergillus fumigatus Proteins, Glycolipids, and Polysaccharides and the Impact on Th Immunity and Vaccination

(2009) S. Bozza et al.   JOURNAL OF IMMUNOLOGY

Cutting Edge: Candida albicans Hyphae Formation Triggers Activation of the Nlrp3 Inflammasome

(2009) S. Joly et al.   JOURNAL OF IMMUNOLOGY

Impaired Interferon‐γ Responses, Increased Interleukin‐17 Expression, and a Tumor Necrosis Factor–α Transcriptional Program in Invasive Aspergillosis

(2009) Darius P. H. Armstrong‐James et al.   JOURNAL OF INFECTIOUS DISEASES

TLR-2, TLR-4 and dectin-1 expression in human monocytes and neutrophils stimulated byParacoccidioides brasiliensis

(2009) Camila Vicente Bonfim et al.   MEDICAL MYCOLOGY

Intranasally delivered siRNA targeting PI3K/Akt/mTOR inflammatory pathways protects from aspergillosis

(2009) P Bonifazi et al.   Mucosal Immunology

Balancing inflammation and tolerance in vivo through dendritic cells by the commensal Candida albicans

(2009) P Bonifazi et al.   Mucosal Immunology

Syk kinase signalling couples to the Nlrp3 inflammasome for anti-fungal host defence

(2009) Olaf Gross et al.   NATURE

Dectin-1 directs T helper cell differentiation by controlling noncanonical NF-κB activation through Raf-1 and Syk

(2009) Sonja I Gringhuis et al.   NATURE IMMUNOLOGY

Human Dectin-1 Deficiency and Mucocutaneous Fungal Infections

(2009) Bart Ferwerda et al.   NEW ENGLAND JOURNAL OF MEDICINE

A HomozygousCARD9Mutation in a Family with Susceptibility to Fungal Infections

(2009) Erik-Oliver Glocker et al.   NEW ENGLAND JOURNAL OF MEDICINE

Genetic Association Analysis of the Functional c.714T>G Polymorphism and Mucosal Expression of Dectin-1 in Inflammatory Bowel Disease

(2009) Hilbert S. de Vries et al.   PLoS One

Impaired dendritic cell maturation and cytokine production in patients with chronic mucocutanous candidiasis with or without APECED

(2008) K. R. Ryan et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Fungal adaptation to the mammalian host: it is a new world, after all

(2008) Nicole M Cooney et al.   CURRENT OPINION IN MICROBIOLOGY

Host–microbe interactions: innate pattern recognition of fungal pathogens

(2008) Frank L van de Veerdonk et al.   CURRENT OPINION IN MICROBIOLOGY

Pathogen specific cytokine release reveals an effect of TLR2 Arg753Gln during Candida sepsis in humans

(2008) Tobias Woehrle et al.   CYTOKINE

Multilocus Sequence Typing of PathogenicCandidaSpecies

(2008) Frank C. Odds et al.   EUKARYOTIC CELL

IL-22 and inflammation: Leukin' through a glass onion

(2008) Lauren A. Zenewicz et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Syk kinase is required for collaborative cytokine production induced through Dectin-1 and Toll-like receptors

(2008) Kevin M. Dennehy et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Airway epithelial cells modify immune responses by inducing an anti-inflammatory microenvironment

(2008) Anja K. Mayer et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Toll-Like Receptor 9 Modulates Immune Responses to Aspergillus fumigatus Conidia in Immunodeficient and Allergic Mice

(2008) H. Ramaprakash et al.   INFECTION AND IMMUNITY

Toll-Like Receptor 9-Dependent Immune Activation by Unmethylated CpG Motifs in Aspergillus fumigatus DNA

(2008) Z. G. Ramirez-Ortiz et al.   INFECTION AND IMMUNITY

Aspergillus fumigatus-induced Interleukin-8 Synthesis by Respiratory Epithelial Cells Is Controlled by the Phosphatidylinositol 3-Kinase, p38 MAPK, and ERK1/2 Pathways and Not by the Toll-like Receptor-MyD88 Pathway

(2008) Viviane Balloy et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Polymorphisms in Toll‐Like Receptor Genes and Susceptibility to Pulmonary Aspergillosis

(2008) A. Carvalho et al.   JOURNAL OF INFECTIOUS DISEASES

Cell mediated immunity to fungi: a reassessment

(2008) Luigina Romani   MEDICAL MYCOLOGY

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(2008) Steven Gribar et al.   MOLECULAR MEDICINE

Defective tryptophan catabolism underlies inflammation in mouse chronic granulomatous disease

(2008) Luigina Romani et al.   NATURE

Impaired TH17 cell differentiation in subjects with autosomal dominant hyper-IgE syndrome

(2008) Joshua D. Milner et al.   NATURE

Toll-like Receptor 4 Polymorphisms and Aspergillosis in Stem-Cell Transplantation

(2008) Pierre-Yves Bochud et al.   NEW ENGLAND JOURNAL OF MEDICINE

The Effect of Toll-Like Receptors and Toll-Like Receptor Genetics in Human Disease

(2007) Stavros Garantziotis et al.   Annual Review of Medicine

Role of TLR1 and TLR6 in the host defense against disseminated candidiasis

(2007) Mihai G. Netea et al.   FEMS IMMUNOLOGY AND MEDICAL MICROBIOLOGY

Activator protein 1 is triggered by Aspergillus fumigatus β-glucans surface-exposed during specific growth stages

(2007) Takahito Toyotome et al.   MICROBIAL PATHOGENESIS

An integrated model of the recognition of Candida albicans by the innate immune system

(2007) Mihai G. Netea et al.   NATURE REVIEWS MICROBIOLOGY