Plasmodium falciparum: new molecular targets with potential for antimalarial drug development

The M17 Leucine Aminopeptidase of the Malaria ParasitePlasmodium falciparum: Importance of Active Site Metal Ions in the Binding of Substrates and Inhibitors

(2009) Selma Maric et al.   BIOCHEMISTRY

Fumagillin and Fumarranol Interact with P. falciparum Methionine Aminopeptidase 2 and Inhibit Malaria Parasite Growth In Vitro and In Vivo

(2009) Xiaochun Chen et al.   CHEMISTRY & BIOLOGY

Homology modeling in drug discovery: current trends and applications

(2009) Claudio N. Cavasotto et al.   DRUG DISCOVERY TODAY

Inhibition of Hypoxanthine-Guanine Phosphoribosyltransferase by Acyclic Nucleoside Phosphonates: A New Class of Antimalarial Therapeutics

(2009) Dianne T. Keough et al.   JOURNAL OF MEDICINAL CHEMISTRY

Failure of artesunate-mefloquine combination therapy for uncomplicated Plasmodium falciparum malaria in southern Cambodia

(2009) William O Rogers et al.   MALARIA JOURNAL

Structural basis for the inhibition of the essentialPlasmodium falciparumM1 neutral aminopeptidase

(2009) Sheena McGowan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Antimalarial Activity of Phenylthiazolyl-Bearing Hydroxamate-Based Histone Deacetylase Inhibitors

(2008) G. S. Dow et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Potent Antimalarial Activity of Histone Deacetylase Inhibitor Analogues

(2008) K. T. Andrews et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Stronger Activity of Human Immunodeficiency Virus Type 1 Protease Inhibitors against Clinical Isolates of Plasmodium vivax than against Those of P. falciparum

(2008) U. Lek-Uthai et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Antimalarial Drugs – What is in Use and What is in the Pipeline

(2008) Martin Schlitzer   ARCHIV DER PHARMAZIE

Structural insights into the Plasmodium falciparum histone deacetylase 1 (PfHDAC-1): A novel target for the development of antimalarial therapy

(2008) Prasenjit Mukherjee et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Clinical Pharmacology of Artemisinin-Based Combination Therapies

(2008) Francesca T Aweeka et al.   CLINICAL PHARMACOKINETICS

HIV Protease Inhibitors Inhibit the Development of Preerythrocytic-StagePlasmodiumParasites

(2008) Charlotte V. Hobbs et al.   JOURNAL OF INFECTIOUS DISEASES

Plasmodium vivax: who cares?

(2008) Mary R Galinski et al.   MALARIA JOURNAL

A green fluorescent protein-based assay for determining gametocyte production in Plasmodium falciparum

(2008) M DIXON et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

Predicting functional residues in Plasmodium falciparum plasmepsins by combining sequence and structural analysis with molecular dynamics simulations

(2008) Pedro A. Valiente et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

EPIDEMIOLOGY: Lower Malaria Numbers Reflect Better Estimates and a Glimmer of Hope

(2008) M. Enserink   SCIENCE

Recent highlights in antimalarial drug resistance and chemotherapy research

(2008) David A. Fidock et al.   TRENDS IN PARASITOLOGY