Role of IL-23 in the pathogenesis of psoriasis: a novel potential therapeutic target?
Published 2014 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Role of IL-23 in the pathogenesis of psoriasis: a novel potential therapeutic target?
Authors
Keywords
-
Journal
EXPERT OPINION ON THERAPEUTIC TARGETS
Volume 18, Issue 5, Pages 513-525
Publisher
Informa Healthcare
Online
2014-02-25
DOI
10.1517/14728222.2014.889686
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Identification of Cellular Pathways of "Type 1," Th17 T Cells, and TNF- and Inducible Nitric Oxide Synthase-Producing Dendritic Cells in Autoimmune Inflammation through Pharmacogenomic Study of Cyclosporine A in Psoriasis
- (2014) A. S. Haider et al. JOURNAL OF IMMUNOLOGY
- Involvement of IL-9 in Th17-Associated Inflammation and Angiogenesis of Psoriasis
- (2013) Tej Pratap Singh et al. PLoS One
- Efficacy and safety of secukinumab in the treatment of moderate-to-severe plaque psoriasis: a randomized, double-blind, placebo-controlled phase II dose-ranging study
- (2012) K.A. Papp et al. BRITISH JOURNAL OF DERMATOLOGY
- Genetics of Psoriasis: Evidence for Epistatic Interaction between Skin Barrier Abnormalities and Immune Deviation
- (2012) Judith G.M. Bergboer et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- CD8+ T Cells in the Lesional Skin of Atopic Dermatitis and Psoriasis Patients Are an Important Source of IFN-γ, IL-13, IL-17, and IL-22
- (2012) DirkJan Hijnen et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- The Emerging Role of IL-17 in the Pathogenesis of Psoriasis: Preclinical and Clinical Findings
- (2012) David A. Martin et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Brodalumab, an Anti–Interleukin-17–Receptor Antibody for Psoriasis
- (2012) Kim A. Papp et al. NEW ENGLAND JOURNAL OF MEDICINE
- Anti–Interleukin-17 Monoclonal Antibody Ixekizumab in Chronic Plaque Psoriasis
- (2012) Craig Leonardi et al. NEW ENGLAND JOURNAL OF MEDICINE
- Apilimod Inhibits the Production of IL-12 and IL-23 and Reduces Dendritic Cell Infiltration in Psoriasis
- (2012) Yumiko Wada et al. PLoS One
- Pivotal Role of Dermal IL-17-Producing γδ T Cells in Skin Inflammation
- (2011) Yihua Cai et al. IMMUNITY
- Interleukin-23: as a drug target for autoimmune inflammatory diseases
- (2011) Chunlei Tang et al. IMMUNOLOGY
- Distinct Roles of IL-23 and IL-17 in the Development of Psoriasis-Like Lesions in a Mouse Model
- (2011) Kimiko Nakajima et al. JOURNAL OF IMMUNOLOGY
- Identification of a Novel Proinflammatory Human Skin-Homing V 9V 2 T Cell Subset with a Potential Role in Psoriasis
- (2011) U. Laggner et al. JOURNAL OF IMMUNOLOGY
- Mast Cells and Neutrophils Release IL-17 through Extracellular Trap Formation in Psoriasis
- (2011) A. M. Lin et al. JOURNAL OF IMMUNOLOGY
- Long-term safety experience of ustekinumab in patients with moderate-to-severe psoriasis (Part I of II): Results from analyses of general safety parameters from pooled Phase 2 and 3 clinical trials
- (2011) Mark Lebwohl et al. JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY
- Therapeutic targeting of the IL-12/23 pathways: generation and characterization of ustekinumab
- (2011) Jacqueline M Benson et al. NATURE BIOTECHNOLOGY
- Neutrophils Activate Plasmacytoid Dendritic Cells by Releasing Self-DNA-Peptide Complexes in Systemic Lupus Erythematosus
- (2011) R. Lande et al. Science Translational Medicine
- Involvement of IL-17F via the induction of IL-6 in psoriasis
- (2010) Sawa Fujishima et al. ARCHIVES OF DERMATOLOGICAL RESEARCH
- Targeting IL-23 in human diseases
- (2010) Mario M D'Elios et al. EXPERT OPINION ON THERAPEUTIC TARGETS
- 8-Methoxypsoralen Plus Ultraviolet A Therapy Acts via Inhibition of the IL-23/Th17 Axis and Induction of Foxp3+ Regulatory T Cells Involving CTLA4 Signaling in a Psoriasis-Like Skin Disorder
- (2010) T. P. Singh et al. JOURNAL OF IMMUNOLOGY
- IL-23-Mediated Psoriasis-Like Epidermal Hyperplasia Is Dependent on IL-17A
- (2010) H. L. Rizzo et al. JOURNAL OF IMMUNOLOGY
- Loss of IL-17-Producing CD8 T Cells during Late Chronic Stage of Pathogenic Simian Immunodeficiency Virus Infection
- (2010) P. Nigam et al. JOURNAL OF IMMUNOLOGY
- A Naturally Occurring, Soluble Antagonist of Human IL-23 Inhibits the Development and In Vitro Function of Human Th17 Cells
- (2010) R. Y. Yu et al. JOURNAL OF IMMUNOLOGY
- Essential Role of IL-17A in the Formation of a Mycobacterial Infection-Induced Granuloma in the Lung
- (2010) Y. Okamoto Yoshida et al. JOURNAL OF IMMUNOLOGY
- Effective Narrow-Band UVB Radiation Therapy Suppresses the IL-23/IL-17 Axis in Normalized Psoriasis Plaques
- (2010) Leanne M. Johnson-Huang et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Integrative Responses to IL-17 and TNF-α in Human Keratinocytes Account for Key Inflammatory Pathogenic Circuits in Psoriasis
- (2010) Andrea Chiricozzi et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Comparison of Ustekinumab and Etanercept for Moderate-to-Severe Psoriasis
- (2010) Christopher E.M. Griffiths et al. NEW ENGLAND JOURNAL OF MEDICINE
- Overrepresentation of IL-17A and IL-22 Producing CD8 T Cells in Lesional Skin Suggests Their Involvement in the Pathogenesis of Psoriasis
- (2010) Pieter C. M. Res et al. PLoS One
- Interleukin-23 production in dendritic cells is negatively regulated by protein phosphatase 2A
- (2010) J. Chang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Serum cytokines and growth factor levels in Japanese patients with psoriasis
- (2009) H. Takahashi et al. CLINICAL AND EXPERIMENTAL DERMATOLOGY
- Reconciling id, ego, and superego within interleukin-23
- (2009) Cristina M. Tato et al. IMMUNOLOGICAL REVIEWS
- Effective treatment of psoriasis with etanercept is linked to suppression of IL-17 signaling, not immediate response TNF genes
- (2009) Lisa C. Zaba et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- AP-1 Activated by Toll-like Receptors Regulates Expression of IL-23 p19
- (2009) Weicheng Liu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Self-RNA–antimicrobial peptide complexes activate human dendritic cells through TLR7 and TLR8
- (2009) Dipyaman Ganguly et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Th17 cells and IL-17 receptor signaling are essential for mucosal host defense against oral candidiasis
- (2009) Heather R. Conti et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Imiquimod-Induced Psoriasis-Like Skin Inflammation in Mice Is Mediated via the IL-23/IL-17 Axis
- (2009) L. van der Fits et al. JOURNAL OF IMMUNOLOGY
- IL-23 Drives Pathogenic IL-17-Producing CD8+ T Cells
- (2009) B. Ciric et al. JOURNAL OF IMMUNOLOGY
- Circulating Th17, Th22, and Th1 Cells Are Increased in Psoriasis
- (2009) Shinji Kagami et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- IL-17-producing CD8+ T lymphocytes from psoriasis skin plaques are cytotoxic effector cells that secrete Th17-related cytokines
- (2009) Consuelo Ortega et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Identification of a human helper T cell population that has abundant production of interleukin 22 and is distinct from TH-17, TH1 and TH2 cells
- (2009) Sara Trifari et al. NATURE IMMUNOLOGY
- Involvement of interleukin-21 in the epidermal hyperplasia of psoriasis
- (2009) Roberta Caruso et al. NATURE MEDICINE
- Psoriasis
- (2009) Frank O. Nestle et al. NEW ENGLAND JOURNAL OF MEDICINE
- γδ T cells: an important source of IL-17
- (2008) Christina L Roark et al. CURRENT OPINION IN IMMUNOLOGY
- IL-17 is Involved inHelicobacter pylori-Induced Gastric Inflammatory Responses in a Mouse Model
- (2008) Satoshi Shiomi et al. HELICOBACTER
- TPA induction leads to a Th17-like response in transgenic K14/VEGF mice: a novel in vivo screening model of psoriasis
- (2008) H. Hvid et al. INTERNATIONAL IMMUNOLOGY
- Serum Levels of IL-17 and IL-22 Are Reduced by Etanercept, but not by Acitretin, in Patients with Psoriasis: a Randomized-Controlled Trial
- (2008) M. Caproni et al. JOURNAL OF CLINICAL IMMUNOLOGY
- Chemerin expression marks early psoriatic skin lesions and correlates with plasmacytoid dendritic cell recruitment
- (2008) Cristina Albanesi et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Psoriasis Vulgaris Lesions Contain Discrete Populations of Th1 and Th17 T Cells
- (2008) Michelle A. Lowes et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Functional Characterization of IL-17F as a Selective Neutrophil Attractant in Psoriasis
- (2008) Hideaki Watanabe et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Resident and “Inflammatory” Dendritic Cells in Human Skin
- (2008) Lisa C. Zaba et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- The Structure of Interleukin-23 Reveals the Molecular Basis of p40 Subunit Sharing with Interleukin-12
- (2008) Patrick J. Lupardus et al. JOURNAL OF MOLECULAR BIOLOGY
- Efficacy and safety of ustekinumab, a human interleukin-12/23 monoclonal antibody, in patients with psoriasis: 76-week results from a randomised, double-blind, placebo-controlled trial (PHOENIX 1)
- (2008) Craig L Leonardi et al. LANCET
- A critical function for transforming growth factor-β, interleukin 23 and proinflammatory cytokines in driving and modulating human TH-17 responses
- (2008) Elisabetta Volpe et al. NATURE IMMUNOLOGY
- Simian immunodeficiency virus–induced mucosal interleukin-17 deficiency promotes Salmonella dissemination from the gut
- (2008) Manuela Raffatellu et al. NATURE MEDICINE
- IL-22 mediates mucosal host defense against Gram-negative bacterial pneumonia
- (2008) Shean J Aujla et al. NATURE MEDICINE
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started