The expanding role of IL-7 and thymic stromal lymphopoietin as therapeutic target for rheumatoid arthritis

Cutting Edge: Inhibition of NF- B-Mediated TSLP Expression by Retinoid X Receptor

(2014) H.-C. Lee et al.   JOURNAL OF IMMUNOLOGY

Thymic Stromal Lymphopoietin Is Up-Regulated in the Skin of Patients With Systemic Sclerosis and Induces Profibrotic Genes and Intracellular Signaling That Overlap With Those Induced by Interleukin-13 and Transforming Growth Factor β

(2013) Romy B. Christmann et al.   ARTHRITIS AND RHEUMATISM

Interleukin-7 is produced by afferent lymphatic vessels and supports lymphatic drainage

(2013) M. Iolyeva et al.   BLOOD

Interleukin-7 promotes HIV persistence during antiretroviral therapy

(2013) C. Vandergeeten et al.   BLOOD

Interleukin-7 Facilitates HIV-1 Transmission to Cervico-Vaginal Tissue ex vivo

(2013) Andrea Introini et al.   PLoS Pathogens

Recombinant human interleukin-7 (CYT107) promotes T-cell recovery after allogeneic stem cell transplantation

(2012) M.-A. Perales et al.   BLOOD

IL-7-producing stromal cells are critical for lymph node remodeling

(2012) L. Onder et al.   BLOOD

Are biological targets the final goal for rheumatoid arthritis therapy?

(2012) Puja Sharma et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

IL-7 modulates B cells survival and activation by inducing BAFF and CD70 expression in T cells

(2012) Stefano Sammicheli et al.   JOURNAL OF AUTOIMMUNITY

IL-7 Restores Lymphocyte Functions in Septic Patients

(2012) F. Venet et al.   JOURNAL OF IMMUNOLOGY

The multiple facets of thymic stromal lymphopoietin (TSLP) during allergic inflammation and beyond

(2012) Florence Roan et al.   JOURNAL OF LEUKOCYTE BIOLOGY

IL-7 signaling must be intermittent, not continuous, during CD8+ T cell homeostasis to promote cell survival instead of cell death

(2012) Motoko Y Kimura et al.   NATURE IMMUNOLOGY

Interleukin-7 Links T Lymphocyte and Intestinal Epithelial Cell Homeostasis

(2012) Shabnam Shalapour et al.   PLoS One

Anti-IL-7 receptor-  reverses established type 1 diabetes in nonobese diabetic mice by modulating effector T-cell function

(2012) L.-F. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Interleukin-32-induced thymic stromal lymphopoietin plays a critical role in macrophage differentiation through the activation of caspase-1 in vitro

(2012) Hyun-Ja Jeong et al.   ARTHRITIS RESEARCH & THERAPY

STAT3 is critical to promote inflammatory cytokines and RANKL expression in inflammatory arthritis

(2012) Takeshi Miyamoto et al.   ARTHRITIS RESEARCH & THERAPY

Epigallocatechin-3-O-gallate inhibits the production of thymic stromal lymphopoietin by the blockade of caspase-1/NF-κB pathway in mast cells

(2011) Phil-Dong Moon et al.   AMINO ACIDS

The suppression of thymic stromal lymphopoietin expression by selenium

(2011) Phil-Dong Moon et al.   AMINO ACIDS

Characterization of interleukin-7 and interleukin-7 receptor in the pathogenesis of rheumatoid arthritis

(2011) Sarah R. Pickens et al.   ARTHRITIS AND RHEUMATISM

Critical proinflammatory role of thymic stromal lymphopoietin and its receptor in experimental autoimmune arthritis

(2011) S. A. Y. Hartgring et al.   ARTHRITIS AND RHEUMATISM

Decreases in IL-7 levels during antiretroviral treatment of HIV infection suggest a primary mechanism of receptor-mediated clearance

(2011) J. N. Hodge et al.   BLOOD

IL-7 Engages Multiple Mechanisms to Overcome Chronic Viral Infection and Limit Organ Pathology

(2011) Marc Pellegrini et al.   CELL

Naringenin suppresses the production of thymic stromal lymphopoietin through the blockade of RIP2 and caspase-1 signal cascade in mast cells

(2011) Phil-Dong Moon et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Berberine inhibits the production of thymic stromal lymphopoietin by the blockade of caspase-1/NF-κB pathway in mast cells

(2011) Phil-Dong Moon et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Thymic stromal lymphopoietin

(2010) Rui He et al.   Annals of the New York Academy of Sciences

Blockade of the interleukin-7 receptor inhibits collagen-induced arthritis and is associated with reduction of T cell activity and proinflammatory mediators

(2010) Sarita A. Y. Hartgring et al.   ARTHRITIS AND RHEUMATISM

IL-7 Promotes T Cell Viability, Trafficking, and Functionality and Improves Survival in Sepsis

(2010) J. Unsinger et al.   JOURNAL OF IMMUNOLOGY

Elevated expression of interleukin-7 receptor in inflamed joints mediates interleukin-7-induced immune activation in rheumatoid arthritis

(2009) Sarita A. Y. Hartgring et al.   ARTHRITIS AND RHEUMATISM

IL-7 administration drives T cell-cycle entry and expansion in HIV-1 infection

(2009) I. Sereti et al.   BLOOD

IL7-hCD25 and IL7-Cre BAC transgenic mouse lines: New tools for analysis of IL-7 expressing cells

(2009) John F. Repass et al.   GENESIS

Structural and Biophysical Studies of the Human IL-7/IL-7Rα Complex

(2009) Craig A. McElroy et al.   STRUCTURE

Identification of interleukin-7 as a candidate disease mediator in spondylarthritis

(2008) Markus Rihl et al.   ARTHRITIS AND RHEUMATISM

Thymic stromal lymphopoietin: a new cytokine in asthma

(2008) Y ROCHMAN et al.   CURRENT OPINION IN PHARMACOLOGY

Mycobacterium bovis Bacillus Calmette-Guerin suppresses inflammatory Th2 responses by inducing functional alteration of TSLP-activated dendritic cells

(2008) T. Yokoi et al.   INTERNATIONAL IMMUNOLOGY

Administration of rhIL-7 in humans increases in vivo TCR repertoire diversity by preferential expansion of naive T cell subsets

(2008) Claude Sportès et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Interleukin-7 in rheumatoid arthritis

(2008) S. M. Churchman et al.   RHEUMATOLOGY

Role of interleukin-7 in degenerative and inflammatory joint diseases

(2008) Joel AG van Roon et al.   ARTHRITIS RESEARCH & THERAPY