Acid-sensing ion channel 1a-mediated calcium influx regulates apoptosis of endplate chondrocytes in intervertebral discs

Acid-sensing ion channel 1a is involved in acid-induced osteoclastogenesis by regulating activation of the transcription factor NFATc1

(2013) Xia Li et al.   FEBS LETTERS

Blockade of acid-sensing ion channels protects articular chondrocytes from acid-induced apoptotic injury

(2012) Wei Hu et al.   INFLAMMATION RESEARCH

Immunohistochemical localization of acid-sensing ion channel 2 (ASIC2) in cutaneous Meissner and Pacinian corpuscles of Macaca fascicularis

(2012) R. Cabo et al.   NEUROSCIENCE LETTERS

Acid Sensing Ion Channel 1 in Lateral Hypothalamus Contributes to Breathing Control

(2012) Nana Song et al.   PLoS One

Altered Mitochondrial Function in Type 2 Granular Corneal Dystrophy

(2011) Tae-im Kim et al.   AMERICAN JOURNAL OF PATHOLOGY

Chronic hypoxia upregulates pulmonary arterial ASIC1: a novel mechanism of enhanced store-operated Ca2+ entry and receptor-dependent vasoconstriction

(2011) Nikki L. Jernigan et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Role of Acid-Sensing Ion Channel 1a in the Secondary Damage of Traumatic Spinal Cord Injury

(2011) Rong Hu et al.   ANNALS OF SURGERY

Extracellular acidification induces connective tissue growth factor production through proton-sensing receptor OGR1 in human airway smooth muscle cells

(2011) Shinichi Matsuzaki et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Inhibition of acid-sensing ion channels by amiloride protects rat articular chondrocytes from acid-induced apoptosis via a mitochondrial-mediated pathway

(2011) Chao Rong et al.   CELL BIOLOGY INTERNATIONAL

Study to determine the presence of progenitor cells in the degenerated human cartilage endplates

(2011) Bo Huang et al.   EUROPEAN SPINE JOURNAL

Acid-Sensing Ion Channels Contribute to the Effect of Acidosis on the Function of Dendritic Cells

(2011) J. Tong et al.   JOURNAL OF IMMUNOLOGY

PICK1 regulates the trafficking of ASIC1a and acidotoxicity in a BAR domain lipid binding-dependent manner

(2011) Wenying Jin et al.   Molecular Brain

Modulation of ROS/MAPK signaling pathways by okadaic acid leads to cell death via, mitochondrial mediated caspase-dependent mechanism

(2010) Jayaraj Ravindran et al.   APOPTOSIS

Inhibition of acid-sensing ion channels in articular chondrocytes by amiloride attenuates articular cartilage destruction in rats with adjuvant arthritis

(2010) Feng-Lai Yuan et al.   INFLAMMATION RESEARCH

Activation of Acid-sensing Ion Channel 1a (ASIC1a) by Surface Trafficking

(2010) Sunghee Chai et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Acid-sensing ion channel 1a mediates acid-induced increases in intracellular calcium in rat articular chondrocytes

(2010) Feng-Lai Yuan et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

MSC response to pH levels found in degenerating intervertebral discs

(2009) Karin Wuertz et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Calcineurin Inhibitors Promote Chondrogenic Marker Expression of Dedifferentiated Human Adult Chondrocytes via Stimulation of Endogenous TGFβ1 Production

(2009) Anna E. van der Windt et al.   TISSUE ENGINEERING PART A

Pharmacological enhancement of disc diffusion and differentiation of healthy, ageing and degenerated discs

(2008) S. Rajasekaran et al.   EUROPEAN SPINE JOURNAL

Acid Sensing Ion Channels in Dorsal Spinal Cord Neurons

(2008) A. Baron et al.   JOURNAL OF NEUROSCIENCE

Soft Substrate Up-regulates the Interaction of STIM1 with Store-operated Ca2+ Channels That Lead to Normal Epithelial Cell Apoptosis

(2008) Wen-Tai Chiu et al.   MOLECULAR BIOLOGY OF THE CELL

Seizure termination by acidosis depends on ASIC1a

(2008) Adam E Ziemann et al.   NATURE NEUROSCIENCE

ASIC proteins regulate smooth muscle cell migration

(2007) Samira C. Grifoni et al.   MICROVASCULAR RESEARCH