Targeting the anaphase promoting complex: common pathways for viral infection and cancer therapy
Published 2011 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Targeting the anaphase promoting complex: common pathways for viral infection and cancer therapy
Authors
Keywords
-
Journal
EXPERT OPINION ON THERAPEUTIC TARGETS
Volume 15, Issue 6, Pages 767-780
Publisher
Informa Healthcare
Online
2011-03-07
DOI
10.1517/14728222.2011.558008
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- APC/C- and Mad2-mediated degradation of Cdc20 during spindle checkpoint activation
- (2011) Sheng Ge et al. CELL CYCLE
- Pharmacologic Inhibition of the Anaphase-Promoting Complex Induces A Spindle Checkpoint-Dependent Mitotic Arrest in the Absence of Spindle Damage
- (2010) Xing Zeng et al. CANCER CELL
- Crucial Roles for Protein Kinase C Isoforms in Tumor-Specific Killing by Apoptin
- (2010) J. Jiang et al. CANCER RESEARCH
- Persistent Telomere Damage Induces Bypass of Mitosis and Tetraploidy
- (2010) Teresa Davoli et al. CELL
- Strong inducible knockdown of APC/CCdc20does not cause mitotic arrest in human somatic cells
- (2010) Axel J. Baumgarten et al. CELL CYCLE
- Vertebrate cells genetically deficient for Cdc14A or Cdc14B retain DNA damage checkpoint proficiency but are impaired in DNA repair
- (2010) Annamaria Mocciaro et al. JOURNAL OF CELL BIOLOGY
- Orf virus cell cycle regulator, PACR, competes with subunit 11 of the anaphase promoting complex for incorporation into the complex
- (2010) M. Mo et al. JOURNAL OF GENERAL VIROLOGY
- Adenovirus Protein E4orf4 Induces Premature APCCdc20 Activation in Saccharomyces cerevisiae by a Protein Phosphatase 2A-Dependent Mechanism
- (2010) M. Z. Mui et al. JOURNAL OF VIROLOGY
- Compromised Spindle Assembly Checkpoint due to Altered Expression of Ubch10 and Cdc20 in Human Papillomavirus Type 16 E6- and E7-Expressing Keratinocytes
- (2010) D. Patel et al. JOURNAL OF VIROLOGY
- Inactivation and Disassembly of the Anaphase-Promoting Complex during Human Cytomegalovirus Infection Is Associated with Degradation of the APC5 and APC4 Subunits and Does Not Require UL97-Mediated Phosphorylation of Cdh1
- (2010) Karen Tran et al. JOURNAL OF VIROLOGY
- Cohesin cleavage and Cdk inhibition trigger formation of daughter nuclei
- (2010) Raquel A. Oliveira et al. NATURE CELL BIOLOGY
- p53- and p21-dependent premature APC/C–Cdh1 activation in G2 is part of the long-term response to genotoxic stress
- (2010) L Wiebusch et al. ONCOGENE
- Anaphase-promoting complex/cyclosome-Cdh1 coordinates glycolysis and glutaminolysis with transition to S phase in human T lymphocytes
- (2010) S. L. Colombo et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Evidence that Mitotic Exit Is a Better Cancer Therapeutic Target Than Spindle Assembly
- (2009) Hsiao-Chun Huang et al. CANCER CELL
- A Centrosomal Cdc20-APC Pathway Controls Dendrite Morphogenesis in Postmitotic Neurons
- (2009) Albert H. Kim et al. CELL
- A Genome-wide RNAi Screen Identifies Multiple Synthetic Lethal Interactions with the Ras Oncogene
- (2009) Ji Luo et al. CELL
- An essential role for p73 in regulating mitotic cell death
- (2009) W H Toh et al. CELL DEATH AND DIFFERENTIATION
- Restraint of apoptosis during mitosis through interdomain phosphorylation of caspase-2
- (2009) Joshua L Andersen et al. EMBO JOURNAL
- Anin vivostudy of Cdh1/APC in breast cancer formation
- (2009) Takeo Fujita et al. INTERNATIONAL JOURNAL OF CANCER
- Loss of the mammalian APC/C activator FZR1 shortens G1 and lengthens S phase but has little effect on exit from mitosis
- (2009) R. Sigl et al. JOURNAL OF CELL SCIENCE
- Proteasome Subunits Relocalize during Human Cytomegalovirus Infection, and Proteasome Activity Is Necessary for Efficient Viral Gene Transcription
- (2009) K. Tran et al. JOURNAL OF VIROLOGY
- The Adenovirus E4orf4 Protein Induces G2/M Arrest and Cell Death by Blocking Protein Phosphatase 2A Activity Regulated by the B55 Subunit
- (2009) S. Li et al. JOURNAL OF VIROLOGY
- Cyclin-Dependent Kinase 1-Mediated Bcl-xL/Bcl-2 Phosphorylation Acts as a Functional Link Coupling Mitotic Arrest and Apoptosis
- (2009) D. T. Terrano et al. MOLECULAR AND CELLULAR BIOLOGY
- Analysis of Activator-Binding Sites on the APC/C Supports a Cooperative Substrate-Binding Mechanism
- (2009) Mary E. Matyskiela et al. MOLECULAR CELL
- The bioenergetic and antioxidant status of neurons is controlled by continuous degradation of a key glycolytic enzyme by APC/C–Cdh1
- (2009) Angel Herrero-Mendez et al. NATURE CELL BIOLOGY
- DNA damage induced p53 downregulates Cdc20 by direct binding to its promoter causing chromatin remodeling
- (2009) Taraswi Banerjee et al. NUCLEIC ACIDS RESEARCH
- E3 ubiquitin ligase APC/C-Cdh1 accounts for the Warburg effect by linking glycolysis to cell proliferation
- (2009) A. Almeida et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Cell cycle deregulation by a poxvirus partial mimic of anaphase-promoting complex subunit 11
- (2009) M. Mo et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A Cdc20-APC Ubiquitin Signaling Pathway Regulates Presynaptic Differentiation
- (2009) Y. Yang et al. SCIENCE
- Structure of the Anaphase-Promoting Complex/Cyclosome Interacting with a Mitotic Checkpoint Complex
- (2009) F. Herzog et al. SCIENCE
- Regulation of Skp2-p27 Axis by the Cdh1/Anaphase-Promoting Complex Pathway in Colorectal Tumorigenesis
- (2008) Takeo Fujita et al. AMERICAN JOURNAL OF PATHOLOGY
- The Cdc14B-Cdh1-Plk1 Axis Controls the G2 DNA-Damage-Response Checkpoint
- (2008) Florian Bassermann et al. CELL
- Dissection of the APCCdh1-Skp2 Cascade in Breast Cancer
- (2008) T. Fujita et al. CLINICAL CANCER RESEARCH
- Prostate-specific membrane antigen associates with anaphase-promoting complex and induces chromosomal instability
- (2008) S. A. Rajasekaran et al. MOLECULAR CANCER THERAPEUTICS
- Cdc20 and Cks Direct the Spindle Checkpoint-Independent Destruction of Cyclin A
- (2008) Rob Wolthuis et al. MOLECULAR CELL
- Genomic stability and tumour suppression by the APC/C cofactor Cdh1
- (2008) Irene García-Higuera et al. NATURE CELL BIOLOGY
- The APC/C maintains the spindle assembly checkpoint by targeting Cdc20 for destruction
- (2008) Jakob Nilsson et al. NATURE CELL BIOLOGY
- Ras oncogenes: split personalities
- (2008) Antoine E. Karnoub et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- The adenovirus E4orf4 protein induces growth arrest and mitotic catastrophe in H1299 human lung carcinoma cells
- (2008) S Li et al. ONCOGENE
- Profiling Essential Genes in Human Mammary Cells by Multiplex RNAi Screening
- (2008) J. M. Silva et al. SCIENCE
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started