MicroRNAs in adipogenesis and as therapeutic targets for obesity

miR-27a is a negative regulator of adipocyte differentiation via suppressing PPARγ expression

(2010) Sang Yun Kim et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

A deep investigation into the adipogenesis mechanism: Profile of microRNAs regulating adipogenesis by modulating the canonical Wnt/β-catenin signaling pathway

(2010) Limei Qin et al.   BMC GENOMICS

Brown Fat and the Myth of Diet-Induced Thermogenesis

(2010) Leslie P. Kozak   Cell Metabolism

Plasma MicroRNA Profiling Reveals Loss of Endothelial MiR-126 and Other MicroRNAs in Type 2 Diabetes

(2010) Anna Zampetaki et al.   CIRCULATION RESEARCH

Global microRNA expression profiles in insulin target tissues in a spontaneous rat model of type 2 diabetes

(2010) B. M. Herrera et al.   DIABETOLOGIA

An essential role for Dicer in adipocyte differentiation

(2010) Rajini Mudhasani et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Regulation of Adipocyte Differentiation by Activation of Serotonin (5-HT) Receptors 5-HT2AR and 5-HT2CR and Involvement of MicroRNA-448-Mediated Repression of KLF5

(2010) Minako Kinoshita et al.   MOLECULAR ENDOCRINOLOGY

Mammalian microRNAs predominantly act to decrease target mRNA levels

(2010) Huili Guo et al.   NATURE

Adipose tissue angiogenesis as a therapeutic target for obesity and metabolic diseases

(2010) Yihai Cao   NATURE REVIEWS DRUG DISCOVERY

miR-519d Overexpression Is Associated With Human Obesity

(2010) Rosanna Martinelli et al.   Obesity

MiRNA Expression Profile of Human Subcutaneous Adipose and during Adipocyte Differentiation

(2010) Francisco J. Ortega et al.   PLoS One

MicroRNA-210 Regulates Mitochondrial Free Radical Response to Hypoxia and Krebs Cycle in Cancer Cells by Targeting Iron Sulfur Cluster Protein ISCU

(2010) Elena Favaro et al.   PLoS One

The Relationship of Omental and Subcutaneous Adipocyte Size to Metabolic Disease in Severe Obesity

(2010) Jean O'Connell et al.   PLoS One

MicroRNA hsa-miR-138 Inhibits Adipogenic Differentiation of Human Adipose Tissue-Derived Mesenchymal Stem Cells Through Adenovirus EID-1

(2010) Zhuo Yang et al.   STEM CELLS AND DEVELOPMENT

Integration of microRNA changes in vivo identifies novel molecular features of muscle insulin resistance in type 2 diabetes

(2010) Iain J Gallagher et al.   Genome Medicine

microRNA miR-27b impairs human adipocyte differentiation and targets PPARγ

(2009) Michael Karbiener et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Computational identification of hepatitis C virus associated microRNA-mRNA regulatory modules in human livers

(2009) Xinxia Peng et al.   BMC GENOMICS

MicroRNA-125a is over-expressed in insulin target tissues in a spontaneous rat model of Type 2 Diabetes

(2009) Blanca M Herrera et al.   BMC Medical Genomics

Therapeutic microRNA Delivery Suppresses Tumorigenesis in a Murine Liver Cancer Model

(2009) Janaiah Kota et al.   CELL

MicroRNAs: Target Recognition and Regulatory Functions

(2009) David P. Bartel   CELL

AngiomiRs—Key regulators of angiogenesis

(2009) Shusheng Wang et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

MicroRNAs Induced During Adipogenesis that Accelerate Fat Cell Development Are Downregulated in Obesity

(2009) H. Xie et al.   DIABETES

A role ofmiR-27in the regulation of adipogenesis

(2009) Qun Lin et al.   FEBS Journal

miR-199a*, a Bone Morphogenic Protein 2-responsive MicroRNA, Regulates Chondrogenesis via Direct Targeting to Smad1

(2009) Edward A. Lin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Obesity and genetics regulate microRNAs in islets, liver, and adipose of diabetic mice

(2009) Enpeng Zhao et al.   MAMMALIAN GENOME

mir-210: A Sensor for Hypoxic Stress during Tumorigenesis

(2009) Lijoy K. Mathew et al.   MOLECULAR CELL

MicroRNA 132 Regulates Nutritional Stress-Induced Chemokine Production through Repression of SirT1

(2009) Jay C. Strum et al.   MOLECULAR ENDOCRINOLOGY

MicroRNAlet-7Regulates 3T3-L1 Adipogenesis

(2009) Tingwan Sun et al.   MOLECULAR ENDOCRINOLOGY

Cold-Activated Brown Adipose Tissue in Healthy Men

(2009) Wouter D. van Marken Lichtenbelt et al.   NEW ENGLAND JOURNAL OF MEDICINE

Silencing of microRNA-155 in mice during acute inflammatory response leads to derepression of c/ebp Beta and down-regulation of G-CSF

(2009) Jesper Worm et al.   NUCLEIC ACIDS RESEARCH

Expression of miR-31, miR-125b-5p, and miR-326 in the Adipogenic Differentiation Process of Adipose-Derived Stem Cells

(2009) Yan-Feng Tang et al.   OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY

MicroRNAs as potential cancer therapeutics

(2009) P Trang et al.   ONCOGENE

MicroRNA Expression in Human Omental and Subcutaneous Adipose Tissue

(2009) Nora Klöting et al.   PLoS One

miR-375 maintains normal pancreatic  - and  -cell mass

(2009) M. N. Poy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Macrophage infiltration into adipose tissue may promote angiogenesis for adipose tissue remodeling in obesity

(2008) Can Pang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

The cell growth suppressor, mir-126, targets IRS-1

(2008) Jin Zhang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Regulation of hepatitis C virus by microRNA-122: Figure 1

(2008) Catherine L. Jopling   BIOCHEMICAL SOCIETY TRANSACTIONS

Regulation of the expression of components of the exocytotic machinery of insulin-secreting cells by microRNAs

(2008) Pascal Lovis et al.   BIOLOGICAL CHEMISTRY

Toward MicroRNA–Based Therapeutics for Heart Disease

(2008) Eva van Rooij et al.   CIRCULATION RESEARCH

Angiogenesis Associated With Visceral and Subcutaneous Adipose Tissue in Severe Human Obesity

(2008) S. Ledoux et al.   DIABETES

Alterations in MicroRNA Expression Contribute to Fatty Acid-Induced Pancreatic  -Cell Dysfunction

(2008) P. Lovis et al.   DIABETES

The microRNA-30 Family Is Required for Vertebrate Hepatobiliary Development

(2008) Nicholas J. Hand et al.   GASTROENTEROLOGY

PPAR  and C/EBP factors orchestrate adipocyte biology via adjacent binding on a genome-wide scale

(2008) M. I. Lefterova et al.   GENES & DEVELOPMENT

Nonalcoholic steatohepatitis is associated with altered hepatic MicroRNA expression

(2008) Onpan Cheung et al.   HEPATOLOGY

Loss of miRNA biogenesis induces p19Arf-p53 signaling and senescence in primary cells

(2008) Rajini Mudhasani et al.   JOURNAL OF CELL BIOLOGY

Distinct expression of muscle-specific MicroRNAs (myomirs) in brown adipocytes

(2008) Tomas B. Walden et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Critical Role for Transcription Factor C/EBP-  in Regulating the Expression of Death-Associated Protein Kinase 1

(2008) P. Gade et al.   MOLECULAR AND CELLULAR BIOLOGY

Mouse miRNA library to open

(2008) Amber Dance   NATURE

PRDM16 controls a brown fat/skeletal muscle switch

(2008) Patrick Seale et al.   NATURE

Inhibition of HIV-1 by multiple siRNAs expressed from a single microRNA polycistron

(2008) Ying Poi Liu et al.   NUCLEIC ACIDS RESEARCH

The microRNA miR-8 is a conserved negative regulator of Wnt signaling

(2008) J. A. Kennell et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

miR-17-92 cluster accelerates adipocyte differentiation by negatively regulating tumor-suppressor Rb2/p130

(2008) Q. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dicer-dependent endothelial microRNAs are necessary for postnatal angiogenesis

(2008) Y. Suarez et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A computational screen for mouse signaling pathways targeted by microRNA clusters

(2008) J. Xu et al.   RNA

Identification of glucose-regulated miRNAs from pancreatic   cells reveals a role for miR-30d in insulin transcription

(2008) X. Tang et al.   RNA