NF-κB as a therapeutic target in chronic lymphocytic leukemia

Chronic lymphocytic leukemia and treatment resistance in cancer: The role of the p53 pathway

(2011) Thorsten Zenz et al.   CELL CYCLE

Spontaneous programmed death (apoptosis) of B-chronic lymphocytic leukaemia cells following their culture in vitro

(2010) Russell J. Collins et al.   BRITISH JOURNAL OF HAEMATOLOGY

p65 Activity and ZAP-70 Status Predict the Sensitivity of Chronic Lymphocytic Leukemia Cells to the Selective I B Kinase Inhibitor BMS-345541

(2009) M. Lopez-Guerra et al.   CLINICAL CANCER RESEARCH

Curcumin Inhibits Prosurvival Pathways in Chronic Lymphocytic Leukemia B Cells and May Overcome Their Stromal Protection in Combination with EGCG

(2009) A. K. Ghosh et al.   CLINICAL CANCER RESEARCH

Rituximab, Fludarabine, Cyclophosphamide, and Mitoxantrone: A New, Highly Active Chemoimmunotherapy Regimen for Chronic Lymphocytic Leukemia

(2009) Francesc Bosch et al.   JOURNAL OF CLINICAL ONCOLOGY

Rel A Is an Independent Biomarker of Clinical Outcome in Chronic Lymphocytic Leukemia

(2009) Saman Hewamana et al.   JOURNAL OF CLINICAL ONCOLOGY

Overexpression of TOSO in CLL is triggered by B-cell receptor signaling and associated with progressive disease

(2008) C. P. Pallasch et al.   BLOOD

Mcl-1 expression has in vitro and in vivo significance in chronic lymphocytic leukemia and is associated with other poor prognostic markers

(2008) C. Pepper et al.   BLOOD

The NF- B subunit Rel A is associated with in vitro survival and clinical disease progression in chronic lymphocytic leukemia and represents a promising therapeutic target

(2008) S. Hewamana et al.   BLOOD

Maintenance of Constitutive I B Kinase Activity by Glycogen Synthase Kinase-3 /  in Pancreatic Cancer

(2008) W. Wilson et al.   CANCER RESEARCH

Shared Principles in NF-κB Signaling

(2008) Matthew S. Hayden et al.   CELL

The Novel Nuclear Factor- B Inhibitor LC-1 Is Equipotent in Poor Prognostic Subsets of Chronic Lymphocytic Leukemia and Shows Strong Synergy with Fludarabine

(2008) S. Hewamana et al.   CLINICAL CANCER RESEARCH

Chronic lymphocytic leukaemia

(2008) G Dighiero et al.   LANCET

BCL-2 phosphorylation modulates sensitivity to the BH3 mimetic GX15-070 (Obatoclax) and reduces its synergistic interaction with bortezomib in chronic lymphocytic leukemia cells

(2008) P Pérez-Galán et al.   LEUKEMIA

Tcl1 functions as a transcriptional regulator and is directly involved in the pathogenesis of CLL

(2008) Y. Pekarsky et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Apoptosis: controlled demolition at the cellular level

(2007) Rebecca C. Taylor et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY