Hsp90 as a therapeutic target in patients with oesophageal carcinoma

Targeting Hsp90 prevents escape of breast cancer cells from tyrosine kinase inhibition

(2011) Itai Pashtan et al.   CELL CYCLE

Treatment of Esophageal Cancer Based on Histology

(2009) Daniel T. Chang et al.   AMERICAN JOURNAL OF CLINICAL ONCOLOGY-CANCER CLINICAL TRIALS

First-line therapy for chronic myeloid leukemia: Past, present, and future

(2009) Carolina Pavlovsky et al.   AMERICAN JOURNAL OF HEMATOLOGY

Hsp90 is expressed and represents a therapeutic target in human oesophageal cancer using the inhibitor 17-allylamino-17-demethoxygeldanamycin

(2009) X Wu et al.   BRITISH JOURNAL OF CANCER

Toward Noninvasive Genomic Screening of Lung Cancer Patients

(2009) Lecia V. Sequist et al.   JOURNAL OF CLINICAL ONCOLOGY

BIIB021, an orally available, fully synthetic small-molecule inhibitor of the heat shock protein Hsp90

(2009) K. Lundgren et al.   MOLECULAR CANCER THERAPEUTICS

Hsp90 inhibitor PU-H71, a multimodal inhibitor of malignancy, induces complete responses in triple-negative breast cancer models

(2009) E. Caldas-Lopes et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

P-Glycoprotein-Mediated Resistance to Hsp90-Directed Therapy Is Eclipsed by the Heat Shock Response

(2008) A. K. McCollum et al.   CANCER RESEARCH

Hsp90 Inhibition Suppresses Mutant EGFR-T790M Signaling and Overcomes Kinase Inhibitor Resistance

(2008) T. Shimamura et al.   CANCER RESEARCH

Role of Acetylation and Extracellular Location of Heat Shock Protein 90  in Tumor Cell Invasion

(2008) Y. Yang et al.   CANCER RESEARCH

NVP-AUY922: A Novel Heat Shock Protein 90 Inhibitor Active against Xenograft Tumor Growth, Angiogenesis, and Metastasis

(2008) S. A. Eccles et al.   CANCER RESEARCH

Phase II Trial of 17-Allylamino-17-Demethoxygeldanamycin in Patients with Metastatic Melanoma

(2008) D. B. Solit et al.   CLINICAL CANCER RESEARCH

Heat Shock Protein 90 Overexpression Independently Predicts Inferior Disease-Free Survival with Differential Expression of the   and   Isoforms in Gastrointestinal Stromal Tumors

(2008) C.-F. Li et al.   CLINICAL CANCER RESEARCH

Structural and functional coupling of Hsp90- and Sgt1-centred multi-protein complexes

(2008) Minghao Zhang et al.   EMBO JOURNAL

Randomized Phase II Study of Pulse Erlotinib Before or After Carboplatin and Paclitaxel in Current or Former Smokers With Advanced Non–Small-Cell Lung Cancer

(2008) Gregory J. Riely et al.   JOURNAL OF CLINICAL ONCOLOGY

Release of heat shock proteins from human neuroblastoma cells exposed to acrylamide

(2008) Tomoyuki Sumizawa et al.   JOURNAL OF TOXICOLOGICAL SCIENCES

BRAF and NRAS mutations in melanoma: potential relationships to clinical response to HSP90 inhibitors

(2008) U. Banerji et al.   MOLECULAR CANCER THERAPEUTICS

A novel Hsp90 inhibitor to disrupt Hsp90/Cdc37 complex against pancreatic cancer cells

(2008) T. Zhang et al.   MOLECULAR CANCER THERAPEUTICS

Silencing the cochaperone CDC37 destabilizes kinase clients and sensitizes cancer cells to HSP90 inhibitors

(2008) J R Smith et al.   ONCOGENE

Critical regulation of TGF  signaling by Hsp90

(2008) K. H. Wrighton et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA