Targeting CD133 antigen in cancer

Stem-cell-like glioma cells are resistant to TRAIL/Apo2L and exhibit down-regulation of caspase-8 by promoter methylation

(2009) David Capper et al.   ACTA NEUROPATHOLOGICA

Enhanced radiosensitivity and radiation-induced apoptosis in glioma CD133-positive cells by knockdown of SirT1 expression

(2009) Charn-Jung Chang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Different Response of Human Glioma Tumor-initiating Cells to Epidermal Growth Factor Receptor Kinase Inhibitors

(2009) Fabrizio Griffero et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Drug Development Targeting the Glycogen Synthase Kinase-3β (GSK-3β)-Mediated Signal Transduction Pathway: Inhibitors of the Wnt/β-Catenin Signaling Pathway as Novel Anticancer Drugs

(2009) Fumi Takahashi-Yanaga et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Expression of the "stem cell marker" CD133 in pancreas and pancreatic ductal adenocarcinomas

(2008) Heike Immervoll et al.   BMC CANCER

PPARγ agonists inhibit growth and expansion of CD133+ brain tumour stem cells

(2008) W Chearwae et al.   BRITISH JOURNAL OF CANCER

CD133/prominin-1 is a potential therapeutic target for antibody-drug conjugates in hepatocellular and gastric cancers

(2008) L M Smith et al.   BRITISH JOURNAL OF CANCER

CD133 expression is correlated with lymph node metastasis and vascular endothelial growth factor-C expression in pancreatic cancer

(2008) S Maeda et al.   BRITISH JOURNAL OF CANCER

Lapatinib (Tykerb, GW572016) Reverses Multidrug Resistance in Cancer Cells by Inhibiting the Activity of ATP-Binding Cassette Subfamily B Member 1 and G Member 2

(2008) C.-l. Dai et al.   CANCER RESEARCH

Module Map of Stem Cell Genes Guides Creation of Epithelial Cancer Stem Cells

(2008) David J. Wong et al.   Cell Stem Cell

New Insights into the Cell Biology of Hematopoietic Progenitors by Studying Prominin-1 (CD133)

(2008) Nicola Bauer et al.   CELLS TISSUES ORGANS

Stem Cell Marker CD133 Affects Clinical Outcome in Glioma Patients

(2008) F. Zeppernick et al.   CLINICAL CANCER RESEARCH

Sunitinib (Sutent, SU11248), a Small-Molecule Receptor Tyrosine Kinase Inhibitor, Blocks Function of the ATP-Binding Cassette (ABC) Transporters P-Glycoprotein (ABCB1) and ABCG2

(2008) S. Shukla et al.   DRUG METABOLISM AND DISPOSITION

Expression and clinical significance of the stem cell marker CD133 in hepatocellular carcinoma

(2008) W. Song et al.   INTERNATIONAL JOURNAL OF CLINICAL PRACTICE

The utility and limitations of glycosylated human CD133 epitopes in defining cancer stem cells

(2008) Scott Bidlingmaier et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Clinical and biological implications of CD133-positive and CD133-negative cells in glioblastomas

(2008) Kyeung Min Joo et al.   LABORATORY INVESTIGATION

Epigenetic regulation of CD133 and tumorigenicity of CD133+ ovarian cancer cells

(2008) T Baba et al.   ONCOGENE

Identification of CD133-Positive Radioresistant Cells in Atypical Teratoid/ Rhabdoid Tumor

(2008) Shih-Hwa Chiou et al.   PLoS One

c-Myc Is Required for Maintenance of Glioma Cancer Stem Cells

(2008) Jialiang Wang et al.   PLoS One

The role of PTEN/Akt/PI3K signaling in the maintenance and viability of prostate cancer stem-like cell populations

(2008) A. Dubrovska et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Stem Cell-Associated Antigen CD133 (Prominin-1) Is a Molecular Therapeutic Target for Metastatic Melanoma

(2008) Germana Rappa et al.   STEM CELLS

Pluripotent human stem cell lines: what we can learn about cancer initiation

(2008) Tamra E. Werbowetski-Ogilvie et al.   TRENDS IN MOLECULAR MEDICINE

CD133 negative glioma cells form tumors in nude rats and give rise to CD133 positive cells

(2007) Jian Wang et al.   INTERNATIONAL JOURNAL OF CANCER

Expression of CD133-1 and CD133-2 in ovarian cancer

(2007) G. FERRANDINA et al.   INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER