The Hedgehog signalling pathway as a therapeutic target in early breast cancer development

Aberrent hedgehog signaling is an early event in breast cancer development.

(2010) S O'Toole et al.   CANCER RESEARCH

A Primary Xenograft Model of Small-Cell Lung Cancer Reveals Irreversible Changes in Gene Expression Imposed by Culture In vitro

(2009) V. C. Daniel et al.   CANCER RESEARCH

Hedgehog signalling in breast cancer

(2009) M. Kasper et al.   CARCINOGENESIS

Hedgehog-Gli Signaling Pathway Inhibitors as Anticancer Agents

(2009) Neeraj Mahindroo et al.   JOURNAL OF MEDICINAL CHEMISTRY

Selective translocation of intracellular Smoothened to the primary cilium in response to Hedgehog pathway modulation

(2009) Yu Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cyclopamine inhibition of human breast cancer cell growth independent of Smoothened (Smo)

(2008) Xiaomei Zhang et al.   BREAST CANCER RESEARCH AND TREATMENT

Therapeutic Inhibition of Hedgehog-GLI Signaling in Cancer: Epithelial, Stromal, or Stem Cell Targets?

(2008) Ariel Ruiz i Altaba   CANCER CELL

Hedgehog: functions and mechanisms

(2008) M. Varjosalo et al.   GENES & DEVELOPMENT

Hedgehog Drugs Begin To Show Results

(2008) K. Garber   JNCI-Journal of the National Cancer Institute

Alterations in candidate genes PHF2, FANCC, PTCH1 and XPA at chromosomal 9q22.3 region: Pathological significance in early- and late-onset breast carcinoma

(2008) Satyabrata Sinha et al.   Molecular Cancer

A paracrine requirement for hedgehog signalling in cancer

(2008) Robert L. Yauch et al.   NATURE