New antibacterials for the treatment of toxoplasmosis; a patent review

Synthesis and biological evaluation of new 2-alkylaminoethyl-1,1-bisphosphonic acids against Trypanosoma cruzi and Toxoplasma gondii targeting farnesyl diphosphate synthase

(2011) Valeria S. Rosso et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Chemistry and Biology of Macrolide Antiparasitic Agents

(2011) Younjoo Lee et al.   JOURNAL OF MEDICINAL CHEMISTRY

1-(Fluoroalkylidene)-1,1-bisphosphonic acids are potent and selective inhibitors of the enzymatic activity of Toxoplasma gondii farnesyl pyrophosphate synthase

(2011) Sergio H. Szajnman et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Activity of the Histone Deacetylase Inhibitor FR235222 on Toxoplasma gondii: Inhibition of Stage Conversion of the Parasite Cyst Form and Study of New Derivative Compounds

(2010) D. Maubon et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Carbocyclic 6-benzylthioinosine analogues as subversive substrates of Toxoplasma gondii adenosine kinase: Biological activities and selective toxicities

(2010) Omar N. Al Safarjalani et al.   BIOCHEMICAL PHARMACOLOGY

Structure–activity relationships of carbocyclic 6-benzylthioinosine analogues as subversive substrates of Toxoplasma gondii adenosine kinase

(2010) Young Ah Kim et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Nitrogen-Containing Bisphosphonates and Cancer Immunotherapy

(2010) P. Clezardin et al.   CURRENT PHARMACEUTICAL DESIGN

Bisphosphonates: Molecular Mechanisms of Action and Effects on Bone Cells, Monocytes and Macrophages

(2010) A. J. Roelofs et al.   CURRENT PHARMACEUTICAL DESIGN

Bisphosphonates promote apoptosis in murine osteoclasts in vitro and in vivo

(2010) David E. Hughes et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Thiazole, Oxadiazole, and Carboxamide Derivatives of Artemisinin are Highly Selective and Potent Inhibitors ofToxoplasma gondii

(2010) Christopher P. Hencken et al.   JOURNAL OF MEDICINAL CHEMISTRY

Toxoplasma gondii calcium-dependent protein kinase 1 is a target for selective kinase inhibitors

(2010) Kayode K Ojo et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Discovery of Potent and Selective Inhibitors of CDPK1 from C. parvum and T. gondii

(2010) Ryan C. Murphy et al.   ACS Medicinal Chemistry Letters

Targeting Bone Metastases with a Bispecific Anticancer and Antiangiogenic Polymer-Alendronate-Taxane Conjugate

(2009) Keren Miller et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Potent and Selective Inhibition of Acid Sphingomyelinase by Bisphosphonates

(2009) Anke G. Roth et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Calcium-Dependent Signaling and Kinases in Apicomplexan Parasites

(2009) Oliver Billker et al.   Cell Host & Microbe

Drug inhibition of HDAC3 and epigenetic control of differentiation in Apicomplexa parasites

(2009) Alexandre Bougdour et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Design, Synthesis, and X-ray Crystal Structure of Classical and Nonclassical 2-Amino-4-oxo-5-substituted-6-ethylthieno[2,3-d]pyrimidines as Dual Thymidylate Synthase and Dihydrofolate Reductase Inhibitors and as Potential Antitumor Agents

(2009) Aleem Gangjee et al.   JOURNAL OF MEDICINAL CHEMISTRY

Malaria-Infected Mice Live until at Least Day 30 after a New Monomeric Trioxane Combined with Mefloquine Are Administered Together in a Single Low Oral Dose†

(2009) Lauren E. Woodard et al.   JOURNAL OF MEDICINAL CHEMISTRY

A Brief History and Overview ofToxoplasma gondii

(2009) E. A. Innes   Zoonoses and Public Health

7-Deaza-6-benzylthioinosine analogues as subversive substrate of Toxoplasma gondii adenosine kinase: Activities and selective toxicities

(2008) Omar N. Al Safarjalani et al.   BIOCHEMICAL PHARMACOLOGY

Risks and benefits of bisphosphonates

(2008) R E Coleman   BRITISH JOURNAL OF CANCER

Bisphosphonated Benzoxazinorifamycin Prodrugs for the Prevention and Treatment of Osteomyelitis

(2008) Ranga Reddy et al.   ChemMedChem

The Acidocalcisome as a Target for Chemotherapeutic Agents in Protozoan Parasites

(2008) Roberto Docampo et al.   CURRENT PHARMACEUTICAL DESIGN

Anti-infectives Targeting the isoprenoid pathway ofToxoplasma gondii

(2008) Silvia NJ Moreno et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Artemisinin derivatives inhibit Toxoplasma gondii in vitro at multiple steps in the lytic cycle

(2008) John G. D'Angelo et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Potent Dual Thymidylate Synthase and Dihydrofolate Reductase Inhibitors: Classical and Nonclassical 2-Amino-4-oxo-5-arylthio-substituted-6-methylthieno[2,3-d]pyrimidine Antifolates

(2008) Aleem Gangjee et al.   JOURNAL OF MEDICINAL CHEMISTRY

Structure−Activity Relationships of 7-Deaza-6-benzylthioinosine Analogues as Ligands ofToxoplasma gondiiAdenosine Kinase

(2008) Young Ah Kim et al.   JOURNAL OF MEDICINAL CHEMISTRY

Synthesis and biological evaluation of 2-alkylaminoethyl-1,1-bisphosphonic acids against Trypanosoma cruzi and Toxoplasma gondii targeting farnesyl diphosphate synthase

(2007) Sergio H. Szajnman et al.   BIOORGANIC & MEDICINAL CHEMISTRY