Novel NMDA receptor modulators: an update

Subunit-Selective Allosteric Inhibition of Glycine Binding to NMDA Receptors

(2012) K. B. Hansen et al.   JOURNAL OF NEUROSCIENCE

Treatment of stroke with a PSD-95 inhibitor in the gyrencephalic primate brain

(2012) Douglas J. Cook et al.   NATURE

Coumarin-3-carboxylic acid derivatives as potentiators and inhibitors of recombinant and native N-methyl-d-aspartate receptors

(2012) Mark W. Irvine et al.   NEUROCHEMISTRY INTERNATIONAL

Pharmacological modulation of NMDA receptor activity and the advent of negative and positive allosteric modulators

(2012) Daniel T. Monaghan et al.   NEUROCHEMISTRY INTERNATIONAL

TCN 201 selectively blocks GluN2A-containing NMDARs in a GluN1 co-agonist dependent but non-competitive manner

(2012) S. Edman et al.   NEUROPHARMACOLOGY

The NMDA receptor as a target for cognitive enhancement

(2012) Graham L. Collingridge et al.   NEUROPHARMACOLOGY

Multiple signaling pathways involved in stimulation of osteoblast differentiation by N-methyl-D-aspartate receptors activation in vitro

(2011) Jie-li Li et al.   ACTA PHARMACOLOGICA SINICA

Effects of the cognition impairer MK-801 on learning and memory in mice and rats

(2011) F. Josef van der Staay et al.   BEHAVIOURAL BRAIN RESEARCH

Ketamine as a Novel Antidepressant: From Synapse to Behavior

(2011) J W Murrough   CLINICAL PHARMACOLOGY & THERAPEUTICS

Glutamate Binding-Site Ligands of NMDA Receptors

(2011) C. Bonaccorso et al.   CURRENT MEDICINAL CHEMISTRY

Molecular basis of positive allosteric modulation of GluN2B NMDA receptors by polyamines

(2011) Laetitia Mony et al.   EMBO JOURNAL

Molecular basis of NMDA receptor functional diversity

(2011) Pierre Paoletti   EUROPEAN JOURNAL OF NEUROSCIENCE

Structural and Mechanistic Determinants of a Novel Site for Noncompetitive Inhibition of GluN2D-Containing NMDA Receptors

(2011) K. B. Hansen et al.   JOURNAL OF NEUROSCIENCE

Subunit arrangement and phenylethanolamine binding in GluN1/GluN2B NMDA receptors

(2011) Erkan Karakas et al.   NATURE

Associative learning performance is impaired in zebrafish (Danio rerio) by the NMDA-R antagonist MK-801

(2011) Margarette Sison et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

Structure-activity relationships for allosteric NMDA receptor inhibitors based on 2-naphthoic acid

(2011) Blaise Mathias Costa et al.   NEUROPHARMACOLOGY

Targeting glutamate synapses in schizophrenia

(2011) Julie R. Field et al.   TRENDS IN MOLECULAR MEDICINE

New advances in NMDA receptor pharmacology

(2011) Kevin K. Ogden et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Dextromethorphan Plus Ultra Low-Dose Quinidine Reduces Pseudobulbar Affect

(2010) Erik P. Pioro et al.   ANNALS OF NEUROLOGY

NovelN-methyl-d-aspartate receptor antagonists: a review of compounds patented since 2006

(2010) Manuel Koller et al.   EXPERT OPINION ON THERAPEUTIC PATENTS

Quinazolin-4-one Derivatives: A Novel Class of Noncompetitive NR2C/D Subunit-SelectiveN-Methyl-d-aspartate Receptor Antagonists

(2010) Cara A. Mosley et al.   JOURNAL OF MEDICINAL CHEMISTRY

Specific Sites within the Ligand-Binding Domain and Ion Channel Linkers Modulate NMDA Receptor Gating

(2010) I. Talukder et al.   JOURNAL OF NEUROSCIENCE

Structural Determinants of D-Cycloserine Efficacy at the NR1/NR2C NMDA Receptors

(2010) S. M. Dravid et al.   JOURNAL OF NEUROSCIENCE

A Novel Family of Negative and Positive Allosteric Modulators of NMDA Receptors

(2010) B. M. Costa et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Identification and Characterization of Novel NMDA Receptor Antagonists Selective for NR2A- over NR2B-Containing Receptors

(2010) E. Bettini et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Control of Assembly and Function of Glutamate Receptors by the Amino-Terminal Domain

(2010) K. B. Hansen et al.   MOLECULAR PHARMACOLOGY

Glutamate Receptor Ion Channels: Structure, Regulation, and Function

(2010) S. F. Traynelis et al.   PHARMACOLOGICAL REVIEWS

A subunit-selective potentiator of NR2C- and NR2D-containing NMDA receptors

(2010) Praseeda Mullasseril et al.   Nature Communications

Allosteric modulators of NR2B-containing NMDA receptors: molecular mechanisms and therapeutic potential

(2009) Laetitia Mony et al.   BRITISH JOURNAL OF PHARMACOLOGY

Control of NMDA Receptor Function by the NR2 Subunit Amino-Terminal Domain

(2009) H. Yuan et al.   JOURNAL OF NEUROSCIENCE

Mechanism of differential control of NMDA receptor activity by NR2 subunits

(2009) Marc Gielen et al.   NATURE

X-ray structure, symmetry and mechanism of an AMPA-subtype glutamate receptor

(2009) Alexander I. Sobolevsky et al.   NATURE

The discriminative stimulus effects of N-methyl-d-aspartate glycine-site ligands in NMDA antagonist-trained rats

(2009) Katherine L. Nicholson et al.   PSYCHOPHARMACOLOGY

Glutamate-based antidepressants: 20 years on

(2009) Phil Skolnick et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

An Innovative Design to Establish Proof of Concept of the Antidepressant Effects of the NR2B Subunit Selective N-Methyl-D-Aspartate Antagonist, CP-101,606, in Patients With Treatment-Refractory Major Depressive Disorder

(2008) Sheldon H. Preskorn et al.   JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY

NMDA receptors in clinical neurology: excitatory times ahead

(2008) Lorraine V Kalia et al.   LANCET NEUROLOGY

Contribution of Hippocampal and Extra-Hippocampal NR2B-Containing NMDA Receptors to Performance on Spatial Learning Tasks

(2008) Jakob von Engelhardt et al.   NEURON

Structural Rearrangements of NR1/NR2A NMDA Receptors during Allosteric Inhibition

(2008) Marc Gielen et al.   NEURON