NK-1 receptor antagonists as antitumor drugs: a survey of the literature from 2000 to 2011

Development of aprepitant, the first neurokinin-1 receptor antagonist for the prevention of chemotherapy-induced nausea and vomiting

(2011) Richard Hargreaves et al.   Annals of the New York Academy of Sciences

Substance P immunoreactive nerve fibres are related to gastric cancer differentiation status and could promote proliferation and migration of gastric cancer cells

(2011) Fan Feng et al.   CELL BIOLOGY INTERNATIONAL

The NK-1 Receptor: A New Target in Cancer Therapy

(2011) Miguel Munoz et al.   CURRENT DRUG TARGETS

NK-1 Receptor Antagonists: A New Paradigm in Pharmacological Therapy

(2011) M. Munoz et al.   CURRENT MEDICINAL CHEMISTRY

NK-1 as a melanoma target

(2011) Miguel Muñoz et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Paravertebral anesthesia: how substance P and the NK-1 receptor could be involved in regional block and breast cancer recurrence

(2010) Miguel Muñoz et al.   BREAST CANCER RESEARCH AND TREATMENT

A New Frontier in the Treatment of Cancer: NK-1 Receptor Antagonists

(2010) M. Munoz et al.   CURRENT MEDICINAL CHEMISTRY

Neurokinin-1 receptor antagonists: a comprehensive patent survey

(2010) Shih-Chung Huang et al.   EXPERT OPINION ON THERAPEUTIC PATENTS

The NK-1 receptor is expressed in human melanoma and is involved in the antitumor action of the NK-1 receptor antagonist aprepitant on melanoma cell lines

(2010) Miguel Muñoz et al.   LABORATORY INVESTIGATION

NK-1-receptor-mediated lesion of spinal post-synaptic dorsal column neurons might improve intractable visceral pain of cancer origin

(2010) Yun Wang et al.   MEDICAL HYPOTHESES

Targeting the Neurokinin Receptor 1 with Aprepitant: A Novel Antipruritic Strategy

(2010) Sonja Ständer et al.   PLoS One

The NK-1 receptor antagonist aprepitant as a broad spectrum antitumor drug

(2009) Miguel Muñoz et al.   INVESTIGATIONAL NEW DRUGS

Neurokinin 1 Receptor Mediates Membrane Blebbing in HEK293 Cells through a Rho/Rho-associated Coiled-coil Kinase-dependent Mechanism

(2009) John Meshki et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A constitutively active form of neurokinin 1 receptor and neurokinin 1 receptor-mediated apoptosis in glioblastomas

(2009) Toshimasa Akazawa et al.   JOURNAL OF NEUROCHEMISTRY

Expression of substance P and neurokinin-1-receptor in laryngeal cancer: linking chronic inflammation to cancer promotion and progression

(2008) Francisco Esteban et al.   HISTOPATHOLOGY

Cell motility through plasma membrane blebbing

(2008) Oliver T. Fackler et al.   JOURNAL OF CELL BIOLOGY

Cell proliferation associated with actions of the substance P/NK-1 receptor complex in keratocystic odontogenic tumours

(2008) M.A. González Moles et al.   ORAL ONCOLOGY

Detection of stable N-terminal protachykinin A immunoreactivity in human plasma and cerebrospinal fluid

(2008) Andrea Ernst et al.   PEPTIDES

The NK-1 Receptor Is Expressed in Human Primary Gastric and Colon Adenocarcinomas and Is Involved in the Antitumor Action of L-733,060 and the Mitogenic Action of Substance P on Human Gastrointestinal Cancer Cell Lines

(2008) Marisa Rosso et al.   TUMOR BIOLOGY