New macrolide, lincosaminide and streptogramin B antibiotics

CEM-101 Activity against Gram-Positive Organisms

(2010) L. N. Woosley et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Pharmacokinetics of EDP-420 after Ascending Single Oral Doses in Healthy Adult Volunteers

(2009) L.-J. Jiang et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Mutasynthesis of Lincomycin Derivatives with Activity against Drug-Resistant Staphylococci

(2009) D. Ulanova et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Pharmacokinetics of EDP-420 after Multiple Oral Doses in Healthy Adult Volunteers and in a Bioequivalence Study

(2009) L.-J. Jiang et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Distinct Mode of Interaction of a Novel Ketolide Antibiotic That Displays Enhanced Antimicrobial Activity

(2009) E. C. Kouvela et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Intrapulmonary Pharmacokinetics of S-013420, a Novel Bicyclolide Antibacterial, in Healthy Japanese Subjects

(2009) H. Furuie et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

In Vitro Activity of Mirincamycin (U24729A) against Plasmodium falciparum Isolates from Gabon

(2009) J. Held et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

In Vitro Activity of CEM-101 against Streptococcus pneumoniae and Streptococcus pyogenes with Defined Macrolide Resistance Mechanisms

(2009) P. McGhee et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Synthesis of novel macrolide derivatives with imidazo[4,5-b]pyridinyl sulfur contained alkyl side chains and their antibacterial activity

(2009) Peng Xu et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Novel ureas and thioureas of 15-membered azalides with antibacterial activity against key respiratory pathogens

(2009) Mirjana Bukvić Krajačić et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis and antibacterial activity of novel 15-membered macrolide derivatives: 4″-Carbamate, 11,12-cyclic carbonate-4″-carbamate and 11,4″-di-O-arylcarbamoyl analogs of azithromycin

(2009) Shutao Ma et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis and antibacterial activity of novel 11,12-cyclic carbonate azithromycin 4″-O-carbamate derivatives

(2009) Chenchen Ma et al.   JOURNAL OF ANTIBIOTICS

Design, synthesis and antibacterial activity of a novel alkylide: 3-O-(3-aryl-propenyl)clarithromycin derivatives

(2009) Jian-Hua Liang et al.   JOURNAL OF ANTIBIOTICS

Synthesis and biological properties of 4″-O-acyl derivatives of 8a-Aza-8a-homoerythromycin

(2009) Vlado Stimac et al.   JOURNAL OF ANTIBIOTICS

Discovery of Azetidinyl Ketolides for the Treatment of Susceptible and Multidrug Resistant Community-Acquired Respiratory Tract Infections

(2009) Thomas V. Magee et al.   JOURNAL OF MEDICINAL CHEMISTRY

Preparation and biological evaluation of novel leucomycin analogs derived from nitroso Diels–Alder reactions

(2009) Baiyuan Yang et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Synthesis of an Antibacterial Compound Containing a 1,4-Substituted 1H-1,2,3-Triazole: A Scaleable Alternative to the “Click” Reaction

(2009) Roger Hanselmann et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Novel azalides derived from 16-membered macrolides. Part II: Isolation of the linear 9-formylcarboxylic acid and its sequential macrocyclization with an amino alcohol or an azidoamine

(2008) Tomoaki Miura et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Novel 16-membered macrolides modified at C-12 and C-13 positions of midecamycin A1 and miokamycin. Part 1: Synthesis and evaluation of 12,13-carbamate and 12-arylalkylamino-13-hydroxy analogues

(2008) Tomoaki Miura et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Design and synthesis of novel leucomycin analogues modified at the C-3 position. Part II: 3-O-(3-Aryl-2-propenyl)leucomycin analogues

(2008) Takeshi Furuuchi et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Synthesis of 3,6-bicyclolides: A novel class of macrolide antibiotics

(2008) Yonghua Gai et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Synthesis and antibacterial activity of 4″-O-heteroarylcarbamoyl derivatives of macrolide

(2008) Peng Xu et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Design, synthesis, and antibacterial activities of novel 3,6-bicyclolide oximes: Length optimization and zero carbon linker oximes

(2008) Datong Tang et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Macrolides as immunomodulatory medications for the therapy of chronic lung diseases

(2008) Y LOPEZBOADO et al.   CURRENT OPINION IN PHARMACOLOGY

Use of cethromycin, a new ketolide, for treatment of community-acquired respiratory infections

(2008) Margaret R Hammerschlag et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Ketolides: pharmacological profile and rational positioning in the treatment of respiratory tract infections

(2008) Françoise Van Bambeke et al.   EXPERT OPINION ON PHARMACOTHERAPY

Macrolides beyond the conventional antimicrobials: a class of potent immunomodulators

(2008) Evangelos J. Giamarellos-Bourboulis   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Combinatorial biosynthesis of 5-O-desosaminyl erythronolide A as a potent precursor of ketolide antibiotics

(2008) Devi B. Basnet et al.   JOURNAL OF BIOTECHNOLOGY