Recent developments in the inhibitors of neuroinflammation and neurodegeneration: inflammatory oxidative enzymes as a drug target

Mechanisms Underlying Inflammation in Neurodegeneration

(2010) Christopher K. Glass et al.   CELL

Cyclooxygenase-2 expression in astrocytes and microglia in human oligodendroglioma and astrocytoma

(2010) S. G. Temel et al.   JOURNAL OF MOLECULAR HISTOLOGY

Microglial Physiology: Unique Stimuli, Specialized Responses

(2009) Richard M. Ransohoff et al.   Annual Review of Immunology

Pharmacophore modeling and virtual screening for designing potential 5-Lipoxygenase inhibitors

(2009) P. Aparoy et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

CJ-13610, an orally active inhibitor of 5-lipoxygenase is efficacious in preclinical models of pain

(2009) Luz A. Cortes-Burgos et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Eicosanoids in inflammation and cancer: the role of COX-2

(2009) Smita Agarwal et al.   Expert Review of Clinical Immunology

5-lipoxygenase inhibitor zileuton attenuates ischemic brain damage: involvement of matrix metalloproteinase 9

(2009) Xian-Kun Tu et al.   NEUROLOGICAL RESEARCH

The distinct roles of cyclooxygenase-1 and -2 in neuroinflammation: implications for translational research

(2009) Sang-Ho Choi et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Myeloperoxidase Delays Neutrophil Apoptosis Through CD11b/CD18 Integrins and Prolongs Inflammation

(2008) Driss El Kebir et al.   CIRCULATION RESEARCH

Cyclooxygenase-2 in Synaptic Signaling

(2008) Hongwei Yang et al.   CURRENT PHARMACEUTICAL DESIGN

Aberrant Expression of Myeloperoxidase in Astrocytes Promotes Phospholipid Oxidation and Memory Deficits in a Mouse Model of Alzheimer Disease

(2008) Richard A. Maki et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Neuroinflammatory response to lipopolysaccharide is exacerbated in mice genetically deficient in cyclooxygenase-2

(2008) Saba Aid et al.   Journal of Neuroinflammation

INO-4885 [5,10,15,20-Tetra[N-(benzyl-4'-carboxylate)-2-pyridinium]-21H,23H-porphine Iron(III) Chloride], a Peroxynitrite Decomposition Catalyst, Protects the Heart against Reperfusion Injury in Mice

(2008) X.-Y. Jiao et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Expression of myeloperoxidase enhances the chemosensitivity of leukemia cells through the generation of reactive oxygen species and the nitration of protein

(2008) Y Sawayama et al.   LEUKEMIA

Apocynin: Molecular Aptitudes

(2008) J. Stefanska et al.   MEDIATORS OF INFLAMMATION

Selective increase of neuronal cyclooxygenase-2 (COX-2) expression in vulnerable brain regions of rats with experimental Wernicke’s encephalopathy: effect of nimesulide

(2008) Baoying Gu et al.   METABOLIC BRAIN DISEASE

Apocynin improves outcome in experimental stroke with a narrow dose range

(2008) X.N. Tang et al.   NEUROSCIENCE

5-Lipoxygenase gene disruption reduces amyloid-β pathology in a mouse model of Alzheimer’s disease

(2007) Omidreza Firuzi et al.   FASEB JOURNAL