Latest advances in cannabinoid receptor agonists

A review of nabilone in the treatment of chemotherapy-induced nausea and vomiting

(2016) Mark Ware   Therapeutics and Clinical Risk Management

Cannabinoids, Endocannabinoids, and Related Analogs in Inflammation

(2009) Sumner H. Burstein et al.   AAPS Journal

Morpholine containing CB2 selective agonists

(2009) Renée Zindell et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Design and synthesis of novel tri-aryl CB2 selective cannabinoid ligands

(2009) Himanshu Bhattacharjee et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Positive allosteric modulation of the human cannabinoid (CB1) receptor by RTI-371, a selective inhibitor of the dopamine transporter

(2009) Hernán A. Navarro et al.   BRITISH JOURNAL OF PHARMACOLOGY

Emerging strategies for exploiting cannabinoid receptor agonists as medicines

(2009) Roger G Pertwee   BRITISH JOURNAL OF PHARMACOLOGY

The Use of a Synthetic Cannabinoid in the Management of Treatment-Resistant Nightmares in Posttraumatic Stress Disorder (PTSD)

(2009) George A. Fraser   CNS Neuroscience & Therapeutics

Cannabinoid Receptor Agonist 13, a Novel Cannabinoid Agonist: First in Human Pharmacokinetics and Safety

(2009) A. Gardin et al.   DRUG METABOLISM AND DISPOSITION

Emerging role of the cannabinoid receptor CB2 in immune regulation: therapeutic prospects for neuroinflammation

(2009) Guy A. Cabral et al.   EXPERT REVIEWS IN MOLECULAR MEDICINE

Intestinal Lymphatic Transport Enhances the Post-Prandial Oral Bioavailability of a Novel Cannabinoid Receptor Agonist Via Avoidance of First-Pass Metabolism

(2009) Natalie L. Trevaskis et al.   PHARMACEUTICAL RESEARCH

Identification of intracellular carriers for the endocannabinoid anandamide

(2009) M. Kaczocha et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ligands that target cannabinoid receptors in the brain: from THC to anandamide and beyond

(2008) Roger G. Pertwee   ADDICTION BIOLOGY

MBC94, a Conjugable Ligand for Cannabinoid CB2Receptor Imaging

(2008) Mingfeng Bai et al.   BIOCONJUGATE CHEMISTRY

The SAR studies of novel CB2 selective agonists, benzimidazolone derivatives

(2008) Hirofumi Omura et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

CB2 selective sulfamoyl benzamides: Optimization of the amide functionality

(2008) Allan J. Goodman et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Ligand-Binding Architecture of Human CB2 Cannabinoid Receptor: Evidence for Receptor Subtype-Specific Binding Motif and Modeling GPCR Activation

(2008) Ying Pei et al.   CHEMISTRY & BIOLOGY

Recent Advances in the Development of Selective Ligands for the Cannabinoid CB2 Receptor

(2008) John Huffman et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Overview of the Chemical Families of Fatty Acid Amide Hydrolase and Monoacylglycerol Lipase Inhibitors

(2008) Severine Vandevoorde   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Non-redundant Functions of Cyclooxygenases: Oxygenation of Endocannabinoids

(2008) Carol A. Rouzer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Design and Synthesis of a Novel Series ofN-Alkyl Isatin Acylhydrazone Derivatives that Act as Selective Cannabinoid Receptor 2 Agonists for the Treatment of Neuropathic Pain

(2008) Philippe Diaz et al.   JOURNAL OF MEDICINAL CHEMISTRY

Indol-3-yl-tetramethylcyclopropyl Ketones: Effects of Indole Ring Substitution on CB2Cannabinoid Receptor Activity

(2008) Jennifer M. Frost et al.   JOURNAL OF MEDICINAL CHEMISTRY

6-Methoxy-N-alkyl Isatin Acylhydrazone Derivatives as a Novel Series of Potent Selective Cannabinoid Receptor 2 Inverse Agonists: Design, Synthesis, and Binding Mode Prediction

(2008) Philippe Diaz et al.   JOURNAL OF MEDICINAL CHEMISTRY

Cannabinoid Receptors: Where They are and What They do

(2008) K. Mackie   JOURNAL OF NEUROENDOCRINOLOGY

Selective Activation of Cannabinoid CB2 Receptors Suppresses Neuropathic Nociception Induced by Treatment with the Chemotherapeutic Agent Paclitaxel in Rats

(2008) E. J. Rahn et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Characterization of a Cannabinoid CB2 Receptor-Selective Agonist, A-836339 [2,2,3,3-Tetramethyl-cyclopropanecarboxylic Acid [3-(2-Methoxy-ethyl)-4,5-dimethyl-3H-thiazol-(2Z)-ylidene]-amide], Using in Vitro Pharmacological Assays, in Vivo Pain Models, and Pharmacological Magnetic Resonance Imaging

(2008) B. B. Yao et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Crystal structure of the ligand-free G-protein-coupled receptor opsin

(2008) Jung Hee Park et al.   NATURE

Cannabidiol: from an inactive cannabinoid to a drug with wide spectrum of action

(2008) Antonio Waldo Zuardi   REVISTA BRASILEIRA DE PSIQUIATRIA

Should peripheral CB1 cannabinoid receptors be selectively targeted for therapeutic gain?

(2008) George Kunos et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Imine derivatives as new potent and selective CB2 cannabinoid receptor agonists with an analgesic action

(2007) Hiroshi Ohta et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Cannabinoid CB2receptors: a therapeutic target for the treatment of inflammatory and neuropathic pain

(2007) J Guindon et al.   BRITISH JOURNAL OF PHARMACOLOGY

The diverse CB1and CB2receptor pharmacology of three plant cannabinoids: Δ9-tetrahydrocannabinol, cannabidiol and Δ9-tetrahydrocannabivarin

(2007) R G Pertwee   BRITISH JOURNAL OF PHARMACOLOGY

In vitroandin vivocharacterization of A-796260: a selective cannabinoid CB2receptor agonist exhibiting analgesic activity in rodent pain models

(2007) B B Yao et al.   BRITISH JOURNAL OF PHARMACOLOGY

Novel cannabinoid receptors

(2007) A J Brown   BRITISH JOURNAL OF PHARMACOLOGY

PSNCBAM-1, a novel allosteric antagonist at cannabinoid CB1 receptors with hypophagic effects in rats

(2007) J G Horswill et al.   BRITISH JOURNAL OF PHARMACOLOGY

The orphan receptor GPR55 is a novel cannabinoid receptor

(2007) E Ryberg et al.   BRITISH JOURNAL OF PHARMACOLOGY

Nabilone for the Treatment of Pain in Fibromyalgia

(2007) Ryan Quinlan Skrabek et al.   JOURNAL OF PAIN