Microtubule stabilising agents for cancer chemotherapy

Preclinical efficacy spectrum and pharmacokinetics of ixabepilone

(2008) Francis Y. F. Lee et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Pharmacokinetic profile of the microtubule stabilizer patupilone in tumor-bearing rodents and comparison of anti-cancer activity with other MTS in vitro and in vivo

(2008) Terence O’Reilly et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

New taxanes in development

(2008) Cristiano Ferlini et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Ixabepilone: a new microtubule-targeting agent for breast cancer

(2008) Gerald M Higa et al.   Expert Review of Anticancer Therapy

Paclitaxel Binding to Human and Murine MD-2

(2008) Shanta M. Zimmer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Unique Mode of Microtubule Stabilization Induced by Peloruside A

(2008) J. Torin Huzil et al.   JOURNAL OF MOLECULAR BIOLOGY

Patupilone-Induced Apoptosis Is Mediated by Mitochondrial Reactive Oxygen Species through Bim Relocalization to Mitochondria

(2008) N. R. Khawaja et al.   MOLECULAR PHARMACOLOGY

Development of practical syntheses of the marine anticancer agents discodermolide and dictyostatin

(2008) Gordon J. Florence et al.   NATURAL PRODUCT REPORTS

Sagopilone crosses the blood–brain barrier in vivo to inhibit brain tumor growth and metastases

(2008) Jens Hoffmann et al.   NEURO-ONCOLOGY

Ixabepilone: A Novel Antineoplastic Agent with Low Susceptibility to Multiple Tumor Resistance Mechanisms

(2008) L. Vahdat   ONCOLOGIST

Epothilones as Lead Structures for the Synthesis-Based Discovery of New Chemotypes for Microtubule Stabilization

(2007) Fabian Feyen et al.   ACCOUNTS OF CHEMICAL RESEARCH