Challenges in the management of asthma associated with smoking-induced airway diseases

Targeting oxidant-dependent mechanisms for the treatment of respiratory diseases and their comorbidities

(2018) Neil C Thomson   CURRENT OPINION IN PHARMACOLOGY

Cigarette smoking and response to inhaled corticosteroids in COPD

(2018) Surya P. Bhatt et al.   EUROPEAN RESPIRATORY JOURNAL

Respiratory symptoms and small airway dysfunction in current and former smokers without spirometric COPD

(2018) Neil C Thomson   RESPIROLOGY

Role of eosinophils in airway inflammation of chronic obstructive pulmonary disease

(2018) Donald P Tashkin et al.   International Journal of Chronic Obstructive Pulmonary Disease

Predictors of exacerbation risk and response to budesonide in patients with chronic obstructive pulmonary disease: a post-hoc analysis of three randomised trials

(2018) Mona Bafadhel et al.   Lancet Respiratory Medicine

Innovations in asthma therapy: is there a role for inhaled statins?

(2018) Amir A. Zeki et al.   Expert Review of Respiratory Medicine

Asthma and smoking-induced airway disease without spirometric COPD

(2017) Neil C. Thomson   EUROPEAN RESPIRATORY JOURNAL

Effect of erdosteine on the rate and duration of COPD exacerbations: the RESTORE study

(2017) Roberto W. Dal Negro et al.   EUROPEAN RESPIRATORY JOURNAL

Th-2 signature in chronic airway diseases: towards the extinction of asthma−COPD overlap syndrome?

(2017) Borja G. Cosío et al.   EUROPEAN RESPIRATORY JOURNAL

Precision medicine in airway diseases: moving to clinical practice

(2017) Alvar Agustí et al.   EUROPEAN RESPIRATORY JOURNAL

New and developing non-adrenoreceptor small molecule drugs for the treatment of asthma

(2017) Neil C Thomson   EXPERT OPINION ON PHARMACOTHERAPY

Relationship between Fractional Exhaled Nitric Oxide Level and Efficacy of Inhaled Corticosteroid in Asthma-COPD Overlap Syndrome Patients with Different Disease Severity

(2017) Jia-Xi Feng et al.   JOURNAL OF KOREAN MEDICAL SCIENCE

Effectiveness of fluticasone furoate plus vilanterol on asthma control in clinical practice: an open-label, parallel group, randomised controlled trial

(2017) Ashley Woodcock et al.   LANCET

Effect of azithromycin on asthma exacerbations and quality of life in adults with persistent uncontrolled asthma (AMAZES): a randomised, double-blind, placebo-controlled trial

(2017) Peter G Gibson et al.   LANCET

Smoking prevalence and attributable disease burden in 195 countries and territories, 1990–2015: a systematic analysis from the Global Burden of Disease Study 2015

(2017) Marissa B Reitsma et al.   LANCET

Effects of tiotropium on lung function in current smokers and never smokers with bronchial asthma

(2017) Makoto Yoshida et al.   PULMONARY PHARMACOLOGY & THERAPEUTICS

Extrafine compared to non-extrafine particle inhaled corticosteroids in smokers and ex-smokers with asthma

(2017) Claire A. Cox et al.   RESPIRATORY MEDICINE

Oxidative Stress and Bronchial Asthma in Children—Causes or Consequences?

(2017) Milos Jesenak et al.   Frontiers in Pediatrics

Clinical Studies of Statins in Asthma and COPD

(2017) Neil Thomson   Current Molecular Pharmacology

Influence of cigarette smoking on airway inflammation and inhaled corticosteroid treatment in patients with asthma

(2016) Terufumi Shimoda et al.   ALLERGY AND ASTHMA PROCEEDINGS

Assessing small airway impairment in mild-to-moderate smoking asthmatic patients: TABLE 1

(2016) Marco Contoli et al.   EUROPEAN RESPIRATORY JOURNAL

A comparison of COPD patients with and without ACOS in the ECLIPSE study

(2016) Keele E. Wurst et al.   EUROPEAN RESPIRATORY JOURNAL

Omalizumab (anti-IgE) therapy in the asthma–COPD overlap syndrome (ACOS) and its effects on circulating cytokine levels

(2016) Arzu Didem Yalcin et al.   IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY

Roflumilast combined with montelukast versus montelukast alone as add-on treatment in patients with moderate-to-severe asthma

(2016) Eric D. Bateman et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Omalizumab treatment in asthma-COPD overlap syndrome

(2016) Tugba Songul Tat et al.   JOURNAL OF ASTHMA

Severe asthma and asthma-chronic obstructive pulmonary disease syndrome – Authors' reply

(2016) Sally E Wenzel et al.   LANCET

Smoking, Not COPD, as the Disease

(2016) Leonardo M. Fabbri   NEW ENGLAND JOURNAL OF MEDICINE

Clinical Significance of Symptoms in Smokers with Preserved Pulmonary Function

(2016) Prescott G. Woodruff et al.   NEW ENGLAND JOURNAL OF MEDICINE

Tiotropium improves lung function, exacerbation rate, and asthma control, independent of baseline characteristics including age, degree of airway obstruction, and allergic status

(2016) Huib A.M. Kerstjens et al.   RESPIRATORY MEDICINE

Effect of smoking status on the efficacy of the SMART regimen in high risk asthma

(2016) Janine Pilcher et al.   RESPIROLOGY

Combination therapy of inhaled steroids and long-acting beta2-agonists in asthma–COPD overlap syndrome

(2016) Suh-Young Lee et al.   International Journal of Chronic Obstructive Pulmonary Disease

Treatment response according to small airway phenotypes: a real-life observational study

(2016) Katharina Marth et al.   Therapeutic Advances in Respiratory Disease

Addressing corticosteroid insensitivity in adults with asthma

(2016) Neil C. Thomson   Expert Review of Respiratory Medicine

Influence of Current or Former Smoking on Asthma Management and Control

(2016) Louis-Philippe Boulet et al.   Canadian Respiratory Journal

Differential Effects of Inhaled Corticosteroids in Smokers/Ex-Smokers and Nonsmokers with Asthma

(2015) Nicolas Roche et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Asthma–COPD Overlap. Clinical Relevance of Genomic Signatures of Type 2 Inflammation in Chronic Obstructive Pulmonary Disease

(2015) Stephanie A. Christenson et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Characteristics and Prognosis of Never-Smokers and Smokers with Asthma in the Copenhagen General Population Study. A Prospective Cohort Study

(2015) Yunus Çolak et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Simvastatin Suppresses Airway IL-17 and Upregulates IL-10 in Patients With Stable COPD

(2015) Kittipong Maneechotesuwan et al.   CHEST

Randomized trial of allergen-induced asthmatic response in smokers and non-smokers: effects of inhaled corticosteroids

(2015) A. Cahn et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Statement on smoking cessation in COPD and other pulmonary diseases and in smokers with comorbidities who find it difficult to quit

(2015) Carlos A. Jiménez-Ruiz et al.   EUROPEAN RESPIRATORY JOURNAL

Treatment responsiveness of phenotypes of symptomatic airways obstruction in adults

(2015) James Fingleton et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Use of asthma control indicators in measuring inhaled corticosteroid effectiveness in asthmatic smokers: a systematic review

(2015) Claire E. Hayes et al.   JOURNAL OF ASTHMA

Bronchodilating Drugs for Chronic Obstructive Pulmonary Disease: Current Status and Future Trends

(2015) Paolo Montuschi et al.   JOURNAL OF MEDICINAL CHEMISTRY

Roflumilast for asthma: Efficacy findings in non-placebo-controlled comparator and dosing studies

(2015) E.D. Bateman et al.   PULMONARY PHARMACOLOGY & THERAPEUTICS

Roflumilast for asthma: Efficacy findings in placebo-controlled studies

(2015) E.O. Meltzer et al.   PULMONARY PHARMACOLOGY & THERAPEUTICS

Atorvastatin in combination with inhaled beclometasone modulates inflammatory sputum mediators in smokers with asthma

(2015) Neil C. Thomson et al.   PULMONARY PHARMACOLOGY & THERAPEUTICS

A comparison of the efficacy of once-daily fluticasone furoate/vilanterole with twice-daily fluticasone propionate/salmeterol in asthma-COPD overlap syndrome

(2015) Yoshihisa Ishiura et al.   PULMONARY PHARMACOLOGY & THERAPEUTICS

Clinical and Radiologic Disease in Smokers With Normal Spirometry

(2015) Elizabeth A. Regan et al.   JAMA Internal Medicine

The asthma–COPD overlap syndrome: towards a revised taxonomy of chronic airways diseases?

(2015) Eric D Bateman et al.   Lancet Respiratory Medicine

Arachidonic acid metabolites and enzyme transcripts in asthma are altered by cigarette smoking

(2014) N. C. Thomson et al.   ALLERGY

Predictors of Chronic Obstructive Pulmonary Disease Exacerbation Reduction in Response to Daily Azithromycin Therapy

(2014) MeiLan K. Han et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Responsiveness to inhaled corticosteroid treatment in patients with asthma–chronic obstructive pulmonary disease overlap syndrome

(2014) Hyo Seok Lim et al.   ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY

Pharmacological treatment of chronic obstructive pulmonary disease: from evidence-based medicine to phenotyping

(2014) Paolo Montuschi et al.   DRUG DISCOVERY TODAY

Combination Long-Acting β-Agonists and Inhaled Corticosteroids Compared With Long-Acting β-Agonists Alone in Older Adults With Chronic Obstructive Pulmonary Disease

(2014) Andrea S. Gershon et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Targeting the mevalonate cascade as a new therapeutic approach in heart disease, cancer and pulmonary disease

(2014) Behzad Yeganeh et al.   PHARMACOLOGY & THERAPEUTICS

The effect of smoking cessation on airway inflammation in young asthma patients

(2013) C. G. Westergaard et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Randomised controlled trial of azithromycin in smokers with asthma: Table 1–

(2013) Euan J. Cameron et al.   EUROPEAN RESPIRATORY JOURNAL

Effect of montelukast for treatment of asthma in cigarette smokers

(2013) David Price et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Clinical outcomes and inflammatory biomarkers in current smokers and exsmokers with severe asthma

(2013) Neil C. Thomson et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Smoking in Asthma Is Associated with Elevated Levels of Corticosteroid Resistant Sputum Cytokines—An Exploratory Study

(2013) Mark Spears et al.   PLoS One

Chronic cough and sputum production are associated with worse clinical outcomes in stable asthma

(2013) Neil C. Thomson et al.   RESPIRATORY MEDICINE

Azithromycin for prevention of exacerbations in severe asthma (AZISAST): a multicentre randomised double-blind placebo-controlled trial

(2013) Guy G Brusselle et al.   THORAX

Inflammation and corticosteroid responsiveness in ex-, current- and never-smoking asthmatics

(2013) Eef D Telenga et al.   BMC Pulmonary Medicine

Results from a community-based program evaluating the effect of changing smoking status on asthma symptom control

(2012) Teresa To et al.   BMC PUBLIC HEALTH

Global asthma prevalence in adults: findings from the cross-sectional world health survey

(2012) Teresa To et al.   BMC PUBLIC HEALTH

Asthma Guidelines and Smokers

(2012) Neil C. Thomson et al.   CHEST

Long-term macrolide treatment of chronic inflammatory airway diseases: risks, benefits and future developments

(2012) E. J. Cameron et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Smoking influences response to inhaled corticosteroids in patients with asthma: a meta-analysis

(2012) Xueyan Zheng et al.   CURRENT MEDICAL RESEARCH AND OPINION

Selective PDE inhibitors as novel treatments for respiratory diseases

(2012) Clive P Page et al.   CURRENT OPINION IN PHARMACOLOGY

Tiotropium in Asthma Poorly Controlled with Standard Combination Therapy

(2012) Huib A.M. Kerstjens et al.   NEW ENGLAND JOURNAL OF MEDICINE

Effects of tiotropium on lung function in severe asthmatics with or without emphysematous changes

(2012) Makoto Yoshida et al.   PULMONARY PHARMACOLOGY & THERAPEUTICS

Real-life effectiveness of extrafine beclometasone dipropionate/formoterol in adults with persistent asthma according to smoking status

(2012) Guy Brusselle et al.   RESPIRATORY MEDICINE

Pharmacological antioxidant strategies as therapeutic interventions for COPD

(2011) Irfan Rahman   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Fluticasone/Salmeterol Combination Confers Benefits in People With Asthma Who Smoke

(2011) Karine L. Clearie et al.   CHEST

Leukotriene Antagonists as First-Line or Add-on Asthma-Controller Therapy

(2011) David Price et al.   NEW ENGLAND JOURNAL OF MEDICINE

Do asthmatic smokers benefit as much as non-smokers on budesonide/formoterol maintenance and reliever therapy? Results of an open label study

(2011) Onno C.P. van Schayck et al.   RESPIRATORY MEDICINE

Effects of short-term treatment with atorvastatin in smokers with asthma - a randomized controlled trial

(2011) Georgina Braganza et al.   BMC Pulmonary Medicine

Azithromycin induces anti-viral responses in bronchial epithelial cells

(2010) V. Gielen et al.   EUROPEAN RESPIRATORY JOURNAL

Statins enhance the anti-inflammatory effects of inhaled corticosteroids in asthmatic patients through increased induction of indoleamine 2, 3-dioxygenase

(2010) Kittipong Maneechotesuwan et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Effects of Smoking Cessation on Airflow Obstruction and Quality of Life in Asthmatic Smokers

(2010) An-Soo Jang et al.   Allergy Asthma & Immunology Research

The Effects of Inhaled Budesonide on Lung Function in Smokers and Nonsmokers With Mild Persistent Asthma

(2009) Paul M. O'Byrne et al.   CHEST

Effect of low-dose theophylline plus beclometasone on lung function in smokers with asthma: a pilot study

(2009) M. Spears et al.   EUROPEAN RESPIRATORY JOURNAL

The value of self-report assessment of adherence, rhinitis and smoking in relation to asthma control

(2009) Jane Clatworthy et al.   Primary Care Respiratory Journal

Role of HDAC2 in the Pathophysiology of COPD

(2008) Peter J. Barnes   Annual Review of Physiology

Improvements with tiotropium in COPD patients with concomitant asthma

(2007) H. Magnussen et al.   RESPIRATORY MEDICINE