Metabolic alterations and chronic hepatitis C: treatment strategies

Hepatitis C Virus-Infected Patients Are ‘Spared’ from the Metabolic Syndrome but Not from Insulin Resistance. A Comparative Study of Nonalcoholic Fatty Liver Disease and Hepatitis C Virus-Related Steatosis

(2016) Amedeo Lonardo et al.   CANADIAN JOURNAL OF GASTROENTEROLOGY

The Results of Phase III Clinical Trials With Telaprevir and Boceprevir Presented at the Liver Meeting 2010: A New Standard of Care for Hepatitis C Virus Genotype 1 Infection, But With Issues Still Pending

(2011) Jean–Michel Pawlotsky   GASTROENTEROLOGY

Role of insulin resistance and hepatic steatosis in the progression of fibrosis and response to treatment in hepatitis C

(2011) Arun J. Sanyal   LIVER INTERNATIONAL

Insulin Resistance Predicts Rapid Virologic Response to Peginterferon/Ribavirin Combination Therapy in Hepatitis C Genotype 4 Patients

(2010) Mahmoud Khattab et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Replicated Association Between an IL28B Gene Variant and a Sustained Response to Pegylated Interferon and Ribavirin

(2010) Jeanette J. McCarthy et al.   GASTROENTEROLOGY

Statin Therapy Improves Sustained Virologic Response Among Diabetic Patients With Chronic Hepatitis C

(2010) Gowtham A. Rao et al.   GASTROENTEROLOGY

Changes in Insulin Sensitivity and Body Weight During and After Peginterferon and Ribavirin Therapy for Hepatitis C

(2010) Hari S. Conjeevaram et al.   GASTROENTEROLOGY

Early Menopause Is Associated With Lack of Response to Antiviral Therapy in Women With Chronic Hepatitis C

(2010) Erica Villa et al.   GASTROENTEROLOGY

Danoprevir, an HCV NS3/4A protease inhibitor, improves insulin sensitivity in patients with genotype 1 chronic hepatitis C

(2010) Rami Moucari et al.   GUT

Clearance of HCV by Combination Therapy of Pegylated Interferon α-2a and Ribavirin Improves Insulin Resistance

(2010) Hong Joo Kim et al.   Gut and Liver

Serum cholesterol and statin use predict virological response to peginterferon and ribavirin therapy

(2010) Stephen A. Harrison et al.   HEPATOLOGY

Associations between serum lipids and hepatitis C antiviral treatment efficacy

(2010) Darmendra Ramcharran et al.   HEPATOLOGY

Interferon-lambda genotype and low serum low-density lipoprotein cholesterol levels in patients with chronic hepatitis C infection

(2010) Josephine H. Li et al.   HEPATOLOGY

Homozygosity for the patatin-like phospholipase-3/adiponutrin I148M polymorphism influences liver fibrosis in patients with nonalcoholic fatty liver disease

(2010) Luca Valenti et al.   HEPATOLOGY

Patatin-Like phospholipase domain-containing 3 I148M polymorphism, steatosis, and liver damage in chronic hepatitis C

(2010) Luca Valenti et al.   HEPATOLOGY

Pathogenesis of lipid metabolism disorder in hepatitis C: Polyunsaturated fatty acids counteract lipid alterations induced by the core protein

(2010) Hideyuki Miyoshi et al.   JOURNAL OF HEPATOLOGY

Insulin resistance and sustained virological response in hepatitis C: from bench to bedside

(2010) Manuel Romero-Gómez   LIVER INTERNATIONAL

The homeostasis model assessment of the insulin resistance score is not predictive of a sustained virological response in chronic hepatitis C patients

(2010) Giovanna Fattovich et al.   LIVER INTERNATIONAL

Hepatitis C Virus Infection and the Risk of Coronary Disease

(2009) Adeel A. Butt et al.   CLINICAL INFECTIOUS DISEASES

Diabetes Mellitus Is Associated with Impaired Response to Antiviral Therapy in Chronic Hepatitis C Infection

(2009) Hesham M. Elgouhari et al.   DIGESTIVE DISEASES AND SCIENCES

Whole-Body Insulin Sensitivity Index Is a Highly Specific Predictive Marker for Virological Response to Peginterferon Plus Ribavirin Therapy in Chronic Hepatitis C Patients with Genotype 1b and High Viral Load

(2009) Toshihiko Mizuta et al.   DIGESTIVE DISEASES AND SCIENCES

Hepatitis C and diabetes: the inevitable coincidence?

(2009) Amedeo Lonardo et al.   Expert Review of Anti-Infective Therapy

Insulin resistance and geographical origin: major predictors of liver fibrosis and response to peginterferon and ribavirin in HCV-4

(2009) R. Moucari et al.   GUT

An Open Pilot Study Exploring the Efficacy of Fluvastatin, Pegylated Interferon and Ribavirin in Patients with Hepatitis C Virus Genotype 1b in High Viral Loads

(2009) Hitomi Sezaki et al.   INTERVIROLOGY

Correction of insulin resistance in chronic hepatitis C patients not responding to the standard of care: More questions than answers

(2009) Francesco Negro   JOURNAL OF HEPATOLOGY

Insulin resistance predicts rapid virological response in non-diabetic, non-cirrhotic genotype 1 HCV patients treated with peginterferon alpha-2b plus ribavirin

(2009) Alessandro Grasso et al.   JOURNAL OF HEPATOLOGY

Insulin resistance predicts response to peginterferon-alpha/ribavirin combination therapy in chronic hepatitis C patients

(2009) Chia-Yen Dai et al.   JOURNAL OF HEPATOLOGY

Early prediction of sustained virological response at day 3 of treatment with albinterferon-α-2b in patients with genotype 2/3 chronic hepatitis C

(2009) Avidan U. Neumann et al.   LIVER INTERNATIONAL

Hepatitis C virus, steatosis and lipid abnormalities: clinical and pathogenic data

(2009) Francesco Negro et al.   LIVER INTERNATIONAL

The global burden of hepatitis C

(2009) Daniel Lavanchy   LIVER INTERNATIONAL

Pioglitazone improves virological response to peginterferon α-2b/ribavirin combination therapy in hepatitis C genotype 4 patients with insulin resistance

(2009) Mahmoud Khattab et al.   LIVER INTERNATIONAL

Genetic variation in IL28B and spontaneous clearance of hepatitis C virus

(2009) David L. Thomas et al.   NATURE

IL28B is associated with response to chronic hepatitis C interferon-α and ribavirin therapy

(2009) Vijayaprakash Suppiah et al.   NATURE GENETICS

Insulin resistance is a major determinant of sustained virological response in genotype 1 chronic hepatitis C patients receiving peginterferon α-2b plus ribavirin

(2008) C.-J. CHU et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Incidence of Type 2 Diabetes Mellitus and Glucose Abnormalities in Patients With Chronic Hepatitis C Infection by Response to Treatment: Results of a Cohort Study

(2008) Chiara Giordanino et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Insulin Resistance and Diabetes Increase Fibrosis in the Liver of Patients With Genotype 1 HCV Infection

(2008) Salvatore Petta et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Fluvastatin Inhibits Hepatitis C Replication in Humans

(2008) Ted Bader et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Clinical Significance of Metabolic Syndrome in the Setting of Chronic Hepatitis C Virus Infection

(2008) Ibrahim A. Hanouneh et al.   Clinical Gastroenterology and Hepatology

Hepatitis C virus infection: Molecular pathways to metabolic syndrome

(2008) Muhammad Y. Sheikh et al.   HEPATOLOGY

The hepatitis C virus-associated dysmetabolic syndrome

(2008) Amedeo Lonardo et al.   HEPATOLOGY

Sustained virological response reduces incidence of onset of type 2 diabetes in chronic hepatitis C

(2008) Yasuji Arase et al.   HEPATOLOGY

Dysmetabolic changes associated with HCV: a distinct syndrome?

(2008) Amedeo Lonardo et al.   Internal and Emergency Medicine

Effect of sustained virological response to treatment on the incidence of abnormal glucose values in chronic hepatitis C

(2008) Manuel Romero-Gómez et al.   JOURNAL OF HEPATOLOGY

Insulin Resistance in Chronic Hepatitis C: Association With Genotypes 1 and 4, Serum HCV RNA Level, and Liver Fibrosis

(2007) Rami Moucari et al.   GASTROENTEROLOGY

Baseline cholesterol is associated with the response to antiviral therapy in chronic hepatitis C

(2007) Michael Economou et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Insulin resistance and response to therapy in patients infected with chronic hepatitis C virus genotypes 2 and 3

(2007) Hossein Poustchi et al.   JOURNAL OF HEPATOLOGY

Interplay between oxidative stress and hepatic steatosis in the progression of chronic hepatitis C

(2007) Matteo Vidali et al.   JOURNAL OF HEPATOLOGY