Rho-kinase inhibitors offer a new approach in the treatment of glaucoma

ROCK Inhibitor Enhances Adhesion and Wound Healing of Human Corneal Endothelial Cells

(2013) Aurélien Pipparelli et al.   PLoS One

The Changing Face of Primary Open-Angle Glaucoma in the United States: Demographic and Geographic Changes From 2011 to 2050

(2012) Thasarat S. Vajaranant et al.   AMERICAN JOURNAL OF OPHTHALMOLOGY

Protecting the retinal neurons from glaucoma: Lowering ocular pressure is not enough

(2012) Alessia Pascale et al.   PHARMACOLOGICAL RESEARCH

Ocular Hypotensive Effect of the Rho Kinase Inhibitor AR-12286 in Patients With Glaucoma and Ocular Hypertension

(2011) Robert D. Williams et al.   AMERICAN JOURNAL OF OPHTHALMOLOGY

Rho Kinase Inhibition by Fasudil Has Anti-inflammatory Effects in Hypercholesterolemic Rats

(2011) Zhihong Ma et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Cardioprotective Effect of a Combination of Rho-Kinase Inhibitor and P38 MAPK Inhibitor on Cardiovascular Remodeling and Oxidative Stress in Dahl Rats

(2011) Hiroshi Takeshima et al.   Journal of Atherosclerosis and Thrombosis

Fasudil Inhibits the Proliferation and Contractility and Induces Cell Cycle Arrest and Apoptosis of Human Endometriotic Stromal Cells: A Promising Agent for the Treatment of Endometriosis

(2011) Akitoshi Tsuno et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Pretreatment of Rho Kinase Inhibitor Inhibits Systemic Inflammation and Prevents Endotoxin-Induced Acute Lung Injury in Mice

(2011) Ren Yu Ding et al.   JOURNAL OF SURGICAL RESEARCH

Intraocular Pressure Control and Long-term Visual Field Loss in the Collaborative Initial Glaucoma Treatment Study

(2011) David C. Musch et al.   OPHTHALMOLOGY

Wound Contraction Is Attenuated by Fasudil Inhibition of Rho-Associated Kinase

(2011) Jennifer E. Bond et al.   PLASTIC AND RECONSTRUCTIVE SURGERY

Analysis of responses to the Rho-kinase inhibitor Y-27632 in the pulmonary and systemic vascular bed of the rat

(2010) David B. Casey et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Rho-kinase inhibitor, fasudil, suppresses glioblastoma cell line progression in vitro and in vivo

(2010) Lin Deng et al.   CANCER BIOLOGY & THERAPY

The Effect of the Rho-Associated Protein Kinase Inhibitor, HA-1077, in the Rabbit Ocular Hypertension Model Induced by Water Loading

(2009) Takaki Fukunaga et al.   CURRENT EYE RESEARCH

Uveoscleral outflow – A review

(2009) Albert Alm et al.   EXPERIMENTAL EYE RESEARCH

The trabecular meshwork outflow pathways: Structural and functional aspects

(2009) Ernst R. Tamm   EXPERIMENTAL EYE RESEARCH

Pharmacological Characterization of SAR407899, a Novel Rho-Kinase Inhibitor

(2009) Matthias Löhn et al.   HYPERTENSION

Effects of ROCK inhibitor, Y-27632, on adhesion and mobility in esophageal squamous cell cancer cells

(2009) Lili Wang et al.   MOLECULAR BIOLOGY REPORTS

Novel molecular insights into RhoA GTPase-induced resistance to aqueous humor outflow through the trabecular meshwork

(2008) Min Zhang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Intraocular Pressure–Lowering Effects and Safety of Topical Administration of a Selective ROCK Inhibitor, SNJ-1656, in Healthy Volunteers

(2008) Hidenobu Tanihara   ARCHIVES OF OPHTHALMOLOGY

Applications for ROCK kinase inhibition

(2008) Michael F Olson   CURRENT OPINION IN CELL BIOLOGY

Rho Kinase Inhibition by Fasudil Ameliorates Diabetes-Induced Microvascular Damage

(2008) R. Arita et al.   DIABETES

The role of the actomyosin system in regulating trabecular fluid outflow

(2008) Baohe Tian et al.   EXPERIMENTAL EYE RESEARCH

The mechanism of increasing outflow facility by rho-kinase inhibition with Y-27632 in bovine eyes

(2007) Zhaozeng Lu et al.   EXPERIMENTAL EYE RESEARCH

Enhancing trabecular outflow by disrupting the actin cytoskeleton, increasing uveoscleral outflow with prostaglandins, and understanding the pathophysiology of presbyopia

(2007) Paul L. Kaufman   EXPERIMENTAL EYE RESEARCH