Disease-modifying osteoarthritis drugs:in vitroandin vivodata on the development of DMOADs under investigation

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(2016)   ARTHRITIS AND RHEUMATISM

Effect of Glucosamine Sulfate on Hip Osteoarthritis

(2013) Rianne M. Rozendaal et al.   ANNALS OF INTERNAL MEDICINE

Zoledronic acid reduces knee pain and bone marrow lesions over 1 year: a randomised controlled trial

(2012) Laura Louise Laslett et al.   ANNALS OF THE RHEUMATIC DISEASES

Efficacy and safety of strontium ranelate in the treatment of knee osteoarthritis: results of a double-blind, randomised placebo-controlled trial

(2012) Jean-Yves Reginster et al.   ANNALS OF THE RHEUMATIC DISEASES

A 2-year randomized, double-blind, placebo-controlled, multicenter study of an oral selective iNOS inhibitor in subjects with symptomatic osteoarthritis of the knee

(2012) M.-P. Hellio le Graverand-Gastineau et al.   OSTEOARTHRITIS AND CARTILAGE

American College of Rheumatology 2012 recommendations for the use of nonpharmacologic and pharmacologic therapies in osteoarthritis of the hand, hip, and knee

(2012) Marc C. Hochberg et al.   ARTHRITIS CARE & RESEARCH

Risk factors predictive of joint replacement in a 2-year multicentre clinical trial in knee osteoarthritis using MRI: results from over 6 years of observation

(2011) J.-P. Raynauld et al.   ANNALS OF THE RHEUMATIC DISEASES

Chondroitin sulphate reduces both cartilage volume loss and bone marrow lesions in knee osteoarthritis patients starting as early as 6 months after initiation of therapy: a randomised, double-blind, placebo-controlled pilot study using MRI

(2011) L. M. Wildi et al.   ANNALS OF THE RHEUMATIC DISEASES

Morphea-like skin reactions in patients treated with the cathepsin K inhibitor balicatib

(2011) Thomas M. Rnger et al.   JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY

Imaging longitudinal changes in articular cartilage and bone following doxycycline treatment in a rabbit anterior cruciate ligament transection model of osteoarthritis

(2011) James R. Pinney et al.   MAGNETIC RESONANCE IMAGING

64 ORAL CALCITONIN DEMONSTRATED SYMPTOM-MODIFYING EFFICACY AND INCREASED CARTILAGE VOLUME: RESULTS FROM A 2-YEAR PHASE 3 TRIAL IN PATIENTS WITH OSTEOARTHRITIS OF THE KNEE

(2011) M.A. Karsdal et al.   OSTEOARTHRITIS AND CARTILAGE

Summary and recommendations of the OARSI FDA osteoarthritis Assessment of Structural Change Working Group

(2011) P.G. Conaghan et al.   OSTEOARTHRITIS AND CARTILAGE

Desperately looking for the right target in osteoarthritis: the anti-IL-1 strategy

(2011) Xavier Chevalier et al.   ARTHRITIS RESEARCH & THERAPY

A randomized, double-blind study of AMG 108 (a fully human monoclonal antibody to IL-1R1) in patients with osteoarthritis of the knee

(2011) Stanley B Cohen et al.   ARTHRITIS RESEARCH & THERAPY

Anti-arthritic Action Mechanisms of Natural Chondroitin Sulfate in Human Articular Chondrocytes and Synovial Fibroblasts

(2010) Keisuke Imada et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Phase 1 safety and tolerability study of BMP-7 in symptomatic knee osteoarthritis

(2010) David J Hunter et al.   BMC MUSCULOSKELETAL DISORDERS

Strontium ranelate effect in postmenopausal women with different clinical levels of osteoarthritis

(2010) P. Alexandersen et al.   CLIMACTERIC

Treatment with TNF-α inhibitor infliximab might reduce hand osteoarthritis in patients with rheumatoid arthritis

(2010) M. Güler-Yüksel et al.   OSTEOARTHRITIS AND CARTILAGE

Elevated aggrecanase activity in a rat model of joint injury is attenuated by an aggrecanase specific inhibitor

(2010) P.S. Chockalingam et al.   OSTEOARTHRITIS AND CARTILAGE

Long-term effects of chondroitins 4 and 6 sulfate on knee osteoarthritis: The study on osteoarthritis progression prevention, a two-year, randomized, double-blind, placebo-controlled trial

(2009) André Kahan et al.   ARTHRITIS AND RHEUMATISM

The effect of alendronate on progression of spinal osteophytes and disc-space narrowing

(2008) T Neogi et al.   ANNALS OF THE RHEUMATIC DISEASES

Protective effects of licofelone, a 5-lipoxygenase and cyclo-oxygenase inhibitor, versus naproxen on cartilage loss in knee osteoarthritis: a first multicentre clinical trial using quantitative MRI

(2008) J-P Raynauld et al.   ANNALS OF THE RHEUMATIC DISEASES

The effect of glucosamine and/or chondroitin sulfate on the progression of knee osteoarthritis: A report from the glucosamine/chondroitin arthritis intervention trial

(2008) Allen D. Sawitzke et al.   ARTHRITIS AND RHEUMATISM

OARSI recommendations for the management of hip and knee osteoarthritis, Part II: OARSI evidence-based, expert consensus guidelines

(2008) W. Zhang et al.   OSTEOARTHRITIS AND CARTILAGE

Diacerein inhibits the synthesis of resorptive enzymes and reduces osteoclastic differentiation/survival in osteoarthritic subchondral bone: a possible mechanism for a protective effect against subchondral bone remodelling

(2008) Christelle Boileau et al.   ARTHRITIS RESEARCH & THERAPY

The human anti-IL-1β monoclonal antibody ACZ885 is effective in joint inflammation models in mice and in a proof-of-concept study in patients with rheumatoid arthritis

(2008) Rieke Alten et al.   ARTHRITIS RESEARCH & THERAPY

Total joint replacement after glucosamine sulphate treatment in knee osteoarthritis: results of a mean 8-year observation of patients from two previous 3-year, randomised, placebo-controlled trials

(2007) O. Bruyere et al.   OSTEOARTHRITIS AND CARTILAGE

Relationships between biochemical markers of bone and cartilage degradation with radiological progression in patients with knee osteoarthritis receiving risedronate: the Knee Osteoarthritis Structural Arthritis randomized clinical trial

(2007) P. Garnero et al.   OSTEOARTHRITIS AND CARTILAGE