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Title
Danusertib, an aurora kinase inhibitor
Authors
Keywords
-
Journal
EXPERT OPINION ON INVESTIGATIONAL DRUGS
Volume 21, Issue 3, Pages 383-393
Publisher
Informa Healthcare
Online
2012-01-13
DOI
10.1517/13543784.2012.652303
References
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Related references
Note: Only part of the references are listed.- Phase II study of danusertib (D) in advanced/metastatic breast and ovarian cancers (BC, OC).
- (2017) E. Gallerani et al. JOURNAL OF CLINICAL ONCOLOGY
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- (2017) P. J. Rosen et al. JOURNAL OF CLINICAL ONCOLOGY
- Randomized phase II study of danusertib (D) in second-line metastatic castration-resistant prostate cancer (CRPC).
- (2017) J. P. Bleuse et al. JOURNAL OF CLINICAL ONCOLOGY
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- (2015) Daniel Benten et al. NEOPLASIA
- Aurora kinase A inhibition-induced autophagy triggers drug resistance in breast cancer cells
- (2012) Zhengzhi Zou et al. Autophagy
- Aurora kinase inhibitor patents and agents in clinical testing: an update (2009 – 10)
- (2011) Chun Hei Antonio Cheung et al. EXPERT OPINION ON THERAPEUTIC PATENTS
- Mitosis is not a key target of microtubule agents in patient tumors
- (2011) Edina Komlodi-Pasztor et al. Nature Reviews Clinical Oncology
- Abcg2 Overexpression Represents a Novel Mechanism for Acquired Resistance to the Multi-Kinase Inhibitor Danusertib in BCR-ABL-Positive Cells In Vitro
- (2011) Stefan Balabanov et al. PLoS One
- Influence of pharmacogenetic variability on the pharmacokinetics and toxicity of the aurora kinase inhibitor danusertib
- (2010) Neeltje Steeghs et al. INVESTIGATIONAL NEW DRUGS
- Aurora kinase inhibitors: novel small molecules with promising activity in acute myeloid and Philadelphia-positive leukemias
- (2010) A S Moore et al. LEUKEMIA
- Aurora-C Kinase Deficiency Causes Cytokinesis Failure in Meiosis I and Production of Large Polyploid Oocytes in Mice
- (2010) Kuo-Tai Yang et al. MOLECULAR BIOLOGY OF THE CELL
- A Phase I Dose-Escalation Study of Danusertib (PHA-739358) Administered as a 24-Hour Infusion with and without Granulocyte Colony-Stimulating Factor in a 14-Day Cycle in Patients with Advanced Solid Tumors
- (2009) R. B. Cohen et al. CLINICAL CANCER RESEARCH
- Aurora kinase inhibitors
- (2009) J.J.E.M. Kitzen et al. CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY
- Aurora kinase inhibitors in preclinical and clinical testing
- (2009) Chun Hei Antonio Cheung et al. EXPERT OPINION ON INVESTIGATIONAL DRUGS
- Phase I Pharmacokinetic and Pharmacodynamic Study of the Aurora Kinase Inhibitor Danusertib in Patients With Advanced or Metastatic Solid Tumors
- (2009) Neeltje Steeghs et al. JOURNAL OF CLINICAL ONCOLOGY
- Simultaneous targeting of Aurora kinases and Bcr-Abl kinase by the small molecule inhibitor PHA-739358 is effective against imatinib-resistant BCR-ABL mutations including T315I
- (2008) A. Gontarewicz et al. BLOOD
- Frequent overexpression of Aurora Kinase A in upper gastrointestinal adenocarcinomas correlates with potent antiapoptotic functions
- (2008) Altaf A. Dar et al. CANCER
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