Mipomersen, an antisense apolipoprotein B synthesis inhibitor

Effect of Mipomersen, an Apolipoprotein B Synthesis Inhibitor, on Low-Density Lipoprotein Cholesterol in Patients With Familial Hypercholesterolemia

(2010) Fatima Akdim et al.   AMERICAN JOURNAL OF CARDIOLOGY

Apolipoprotein B synthesis inhibition: results from clinical trials

(2010) Maartje E Visser et al.   CURRENT OPINION IN LIPIDOLOGY

Mipomersen as a potential adjunctive therapy for hypercholesterolemia

(2010) Neeraj Patel et al.   EXPERT OPINION ON PHARMACOTHERAPY

Efficacy and Safety of Mipomersen, an Antisense Inhibitor of Apolipoprotein B, in Hypercholesterolemic Subjects Receiving Stable Statin Therapy

(2010) Fatima Akdim et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Mipomersen, an apolipoprotein B synthesis inhibitor, for lowering of LDL cholesterol concentrations in patients with homozygous familial hypercholesterolaemia: a randomised, double-blind, placebo-controlled trial

(2010) Frederick J Raal et al.   LANCET

Safety signal dampens reception for mipomersen antisense

(2010) Jim Kling   NATURE BIOTECHNOLOGY

Development of Apolipoprotein B Antisense Molecules as a Therapy for Hyperlipidemia

(2009) Tiffany Thomas et al.   Current Atherosclerosis Reports

Effect of apolipoprotein-B synthesis inhibition on liver triglyceride content in patients with familial hypercholesterolemia

(2009) Maartje E. Visser et al.   JOURNAL OF LIPID RESEARCH

Extended-Release Niacin or Ezetimibe and Carotid Intima–Media Thickness

(2009) Allen J. Taylor et al.   NEW ENGLAND JOURNAL OF MEDICINE

Cross-species comparison of in vivo PK/PD relationships for second-generation antisense oligonucleotides targeting apolipoprotein B-100

(2008) Rosie Z. Yu et al.   BIOCHEMICAL PHARMACOLOGY

Lack of Pharmacokinetic Interaction of Mipomersen Sodium (ISIS 301012), a 2′-O-Methoxyethyl Modified Antisense Oligonucleotide Targeting Apolipoprotein B-100 Messenger RNA, with Simvastatin and Ezetimibe

(2008) Rosie Z Yu et al.   CLINICAL PHARMACOKINETICS

Novel nonstatin strategies to lower low-density lipoprotein cholesterol

(2008) Michael H. Davidson   Current Atherosclerosis Reports

Lipoprotein Management in Patients With Cardiometabolic Risk

(2008) John D. Brunzell et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Simvastatin with or without Ezetimibe in Familial Hypercholesterolemia

(2008) John J.P. Kastelein et al.   NEW ENGLAND JOURNAL OF MEDICINE

Inhibition of microsomal triglyceride transfer protein alone or with ezetimibe in patients with moderate hypercholesterolemia

(2008) Frederick F Samaha et al.   Nature clinical practice. Cardiovascular medicine