The clinical development of FLT3 inhibitors in acute myeloid leukemia
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Title
The clinical development of FLT3 inhibitors in acute myeloid leukemia
Authors
Keywords
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Journal
EXPERT OPINION ON INVESTIGATIONAL DRUGS
Volume 20, Issue 10, Pages 1377-1395
Publisher
Informa Healthcare
Online
2011-09-07
DOI
10.1517/13543784.2011.611802
References
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Note: Only part of the references are listed.- FLT3 ligand impedes the efficacy of FLT3 inhibitors in vitro and in vivo
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- Phase IIB Trial of Oral Midostaurin (PKC412), the FMS-Like Tyrosine Kinase 3 Receptor (FLT3) and Multi-Targeted Kinase Inhibitor, in Patients With Acute Myeloid Leukemia and High-Risk Myelodysplastic Syndrome With Either Wild-Type or Mutated FLT3
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- Complete resolution of leukemia cutis with sorafenib in an acute myeloid leukemia patient with FLT3-ITD mutation
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- Identification ofN-(5-tert-Butyl-isoxazol-3-yl)-N′-{4-[7-(2-morpholin-4-yl-ethoxy)imidazo[2,1-b][1,3]benzothiazol-2-yl]phenyl}urea Dihydrochloride (AC220), a Uniquely Potent, Selective, and Efficacious FMS-Like Tyrosine Kinase-3 (FLT3) Inhibitor
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- (2008) Chie Nishioka et al. LEUKEMIA RESEARCH
- Sorafenib (Nexavar®) induces molecular remission and regression of extramedullary disease in a patient with FLT3-ITD+ acute myeloid leukemia
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