Novel opioid antagonists for opioid-induced bowel dysfunction

Opioid antagonists for prevention and treatment of opioid-induced gastrointestinal effects

(2010) Peter Holzer   Current Opinion in Anesthesiology

Combined prolonged-release oxycodone and naloxone improves bowel function in patients receiving opioids for moderate-to-severe non-malignant chronic pain: a randomised controlled trial

(2009) O Löwenstein et al.   EXPERT OPINION ON PHARMACOTHERAPY

Novel opioid antagonists for opioid-induced bowel dysfunction and postoperative ileus

(2009) Gerhild Becker et al.   LANCET

Development of Peripheral Opioid Antagonists: New Insights Into Opioid Effects

(2009) Jonathan Moss et al.   MAYO CLINIC PROCEEDINGS

Opioid receptors in the gastrointestinal tract

(2009) Peter Holzer   REGULATORY PEPTIDES

Methylnaltrexone: a novel approach for the management of opioid-induced constipation in patients with advanced illness

(2009) Laura Diego et al.   Expert Review of Gastroenterology & Hepatology

Fixed-ratio combination oxycodone/naloxone compared with oxycodone alone for the relief of opioid-induced constipation in moderate-to-severe noncancer pain

(2008) K. Simpson et al.   CURRENT MEDICAL RESEARCH AND OPINION

A randomised controlled trial with prolonged-release oral oxycodone and naloxone to prevent and reverse opioid-induced constipation

(2008) Winfried Meissner et al.   EUROPEAN JOURNAL OF PAIN

Methylnaltrexone, a new peripherally acting mu-opioid receptor antagonist being evaluated for the treatment of postoperative ileus

(2008) Michael D Kraft   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Opioid Side Effects — Mechanism-Based Therapy

(2008) Charles Berde et al.   NEW ENGLAND JOURNAL OF MEDICINE

Methylnaltrexone for Opioid-Induced Constipation in Advanced Illness

(2008) Jay Thomas et al.   NEW ENGLAND JOURNAL OF MEDICINE

Alvimopan, a peripherally acting mu-opioid receptor (PAM-OR) antagonist for the treatment of opioid-induced bowel dysfunction: Results from a randomized, double-blind, placebo-controlled, dose-finding study in subjects taking opioids for chronic non-cancer pain

(2008) Lynn Webster et al.   PAIN

The Prevalence, Severity, and Impact of Opioid-Induced Bowel Dysfunction: Results of a US and European Patient Survey (PROBE 1)

(2008) Timothy J. Bell et al.   PAIN MEDICINE

Opioid-Induced Bowel Dysfunction

(2007) Jay Thomas   JOURNAL OF PAIN AND SYMPTOM MANAGEMENT