Drugs for insomnia

Long-Term Efficacy and Safety of Zolpidem Extended-Release 12.5 mg, Administered 3 to 7 Nights Per Week for 24 Weeks, in Patients With Chronic Primary Insomnia: A 6-Month, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Multicenter Study

(2017) Andrew D. Krystal et al.   SLEEP

Efficacy and Safety of 6-Month Nightly Ramelteon Administration in Adults with Chronic Primary Insomnia

(2017) Geert Mayer et al.   SLEEP

Efficacy and Safety of Doxepin 1 mg and 3 mg in a 12-week Sleep Laboratory and Outpatient Trial of Elderly Subjects with Chronic Primary Insomnia

(2017) Andrew D. Krystal et al.   SLEEP

Nonrestorative Sleep as a Distinct Component of Insomnia

(2017) Thomas Roth et al.   SLEEP

A 12-Week, Randomized, Double-Blind, Placebo-Controlled Study Evaluating the Effect of Eszopiclone 2 mg on Sleep/Wake Function in Older Adults with Primary and Comorbid Insomnia

(2017) Sonia Ancoli-lsrael et al.   SLEEP

Hypnotics' association with mortality or cancer: a matched cohort study

(2012) Daniel F Kripke et al.   BMJ Open

Benzodiazepines revisited-will we ever learn?

(2011) Malcolm Lader   ADDICTION

Prevalence of psychiatric disorders in community-dwelling older men and women with cognitive impairment no dementia: results from the ESA study

(2011) Olivier Potvin et al.   AGING & MENTAL HEALTH

Memory disorders associated with consumption of drugs: updating through a case/noncase study in the French PharmacoVigilance Database

(2011) Francois Chavant et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Agomelatine: A narrative review

(2011) Koen Demyttenaere   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Efficacy and tolerability of ramelteon in a double-blind, placebo-controlled, crossover study in Japanese patients with chronic primary insomnia

(2011) Masako Kohsaka et al.   Expert Review of Neurotherapeutics

Associations Between Sleep Disorders, Sleep Duration, Quality of Sleep, and Hypertension: Results From the National Health and Nutrition Examination Survey, 2005 to 2008

(2011) Pooja Bansil et al.   Journal of Clinical Hypertension

Risk of Fractures Requiring Hospitalization After an Initial Prescription for Zolpidem, Alprazolam, Lorazepam, or Diazepam in Older Adults

(2011) William D. Finkle et al.   JOURNAL OF THE AMERICAN GERIATRICS SOCIETY

Sleep Duration and Sleep Quality in Relation to 12-Year Cardiovascular Disease Incidence: The MORGEN Study

(2011) Marieke P. Hoevenaar-Blom et al.   SLEEP

Next-Day Effects of Ramelteon (8 mg), Zopiclone (7.5 mg), and Placebo on Highway Driving Performance, Memory Functioning, Psychomotor Performance, and Mood in Healthy Adult Subjects

(2011) Monique A.J. Mets et al.   SLEEP

Long-term safety and efficacy of ramelteon in Japanese patients with chronic insomnia

(2011) Makoto Uchiyama et al.   SLEEP MEDICINE

Efficacy and safety of doxepin 6mg in a four-week outpatient trial of elderly adults with chronic primary insomnia

(2011) Alan Lankford et al.   SLEEP MEDICINE

Serotonin control of sleep-wake behavior

(2011) Jaime M. Monti   SLEEP MEDICINE REVIEWS

Nightly treatment of primary insomnia with prolonged release melatonin for 6 months: a randomized placebo controlled trial on age and endogenous melatonin as predictors of efficacy and safety

(2010) Alan G Wade et al.   BMC Medicine

Orexin Receptor Antagonism, a New Sleep-Promoting Paradigm: An Ascending Single-Dose Study With Almorexant

(2010) P Hoever et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Next-Day Residual Sedative Effect After Nighttime Administration of an Over-the-Counter Antihistamine Sleep Aid, Diphenhydramine, Measured by Positron Emission Tomography

(2010) Dongying Zhang et al.   JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY

Increased Risk of Hospitalization Related to Motor Vehicle Accidents Among People Taking Zolpidem: A Case–Crossover Study

(2010) Yao-Hsu Yang et al.   JOURNAL OF EPIDEMIOLOGY

British Association for Psychopharmacology consensus statement on evidence-based treatment of insomnia, parasomnias and circadian rhythm disorders

(2010) SJ Wilson et al.   JOURNAL OF PSYCHOPHARMACOLOGY

Effect of hypnotic drugs on body balance and standing steadiness

(2010) Monique A.J. Mets et al.   SLEEP MEDICINE REVIEWS

Ramelteon: a review of its therapeutic potential in sleep disorders

(2009) Seithikurippu R. Pandi-Perumal et al.   ADVANCES IN THERAPY

Reduced Orbitofrontal and Parietal Gray Matter in Chronic Insomnia: A Voxel-Based Morphometric Study

(2009) Ellemarije Altena et al.   BIOLOGICAL PSYCHIATRY

Pharmacology of Ramelteon, a Selective MT1/MT2Receptor Agonist: A Novel Therapeutic Drug for Sleep Disorders

(2009) Masaomi Miyamoto   CNS Neuroscience & Therapeutics

Comparative Tolerability of Newer Agents for Insomnia

(2009) Gary Zammit   DRUG SAFETY

Benzodiazepines and Injurious Falls in Community Dwelling Elders

(2009) Antoine Pariente et al.   DRUGS & AGING

Medication Use and Increased Risk of Falls in Hospitalized Elderly Patients

(2009) Mounir Rhalimi et al.   DRUGS & AGING

Immediate- and controlled-release zolpidem ingestions reported to Texas poison centers

(2009) Mathias B Forrester   HUMAN & EXPERIMENTAL TOXICOLOGY

The effect of prolonged-release melatonin on sleep measures and psychomotor performance in elderly patients with insomnia

(2009) Remy Luthringer et al.   INTERNATIONAL CLINICAL PSYCHOPHARMACOLOGY

Efficacy and Safety of Doxepin 1 mg, 3 mg, and 6 mg in Elderly Patients With Primary Insomnia

(2009) Martin Scharf et al.   JOURNAL OF CLINICAL PSYCHIATRY

Highway driving performance and cognitive functioning the morning after bedtime and middle-of-the-night use of gaboxadol, zopiclone and zolpidem

(2009) TIM R. M. LEUFKENS et al.   JOURNAL OF SLEEP RESEARCH

Retrograde effects of triazolam and zolpidem on sleep-dependent motor learning in humans

(2009) PETER T. MORGAN et al.   JOURNAL OF SLEEP RESEARCH

5-HT2A Inverse-Agonists for the Treatment of Insomnia

(2008) Bradley Teegarden et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Antidepressants for the Treatment of Insomnia

(2008) Michael H Wiegand   DRUGS

Effects of prolonged-release melatonin, zolpidem, and their combination on psychomotor functions, memory recall, and driving skills in healthy middle aged and elderly volunteers

(2008) S. Otmani et al.   HUMAN PSYCHOPHARMACOLOGY-CLINICAL AND EXPERIMENTAL

Effects of long-term exposure to ramelteon, a melatonin receptor agonist, on endocrine function in adults with chronic insomnia

(2008) Gary Richardson et al.   HUMAN PSYCHOPHARMACOLOGY-CLINICAL AND EXPERIMENTAL

Melatonin agonist tasimelteon (VEC-162) for transient insomnia after sleep-time shift: two randomised controlled multicentre trials

(2008) Shantha MW Rajaratnam et al.   LANCET

Physiological effects of melatonin: Role of melatonin receptors and signal transduction pathways

(2008) S PANDIPERUMAL et al.   PROGRESS IN NEUROBIOLOGY

Road traffic accident risk related to prescriptions of the hypnotics zopiclone, zolpidem, flunitrazepam and nitrazepam

(2008) Ingebjørg Gustavsen et al.   SLEEP MEDICINE

Low frequency BOLD fluctuations during resting wakefulness and light sleep: A simultaneous EEG-fMRI study

(2007) Silvina G. Horovitz et al.   HUMAN BRAIN MAPPING