Emerging drugs for focal epilepsy

New AMPA antagonists in epilepsy

(2012) Emilio Russo et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Adjunctive perampanel for refractory partial-onset seizures: Randomized phase III study 304

(2012) J. A. French et al.   NEUROLOGY

Randomized phase III study 306: Adjunctive perampanel for refractory partial-onset seizures

(2012) G. L. Krauss et al.   NEUROLOGY

Treatment-emergent psychiatric adverse events of antiepileptic drugs in epilepsy: how can we avoid them?

(2012) Marco Mula   Neuropsychiatry

Retigabine (Ezogabine)

(2011) Emma D. Deeks   CNS DRUGS

Therapeutic potential of new antiinflammatory drugs

(2011) Annamaria Vezzani et al.   EPILEPSIA

Perampanel: A novel, orally active, noncompetitive AMPA-receptor antagonist that reduces seizure activity in rodent models of epilepsy

(2011) Takahisa Hanada et al.   EPILEPSIA

Incidence of epilepsy: A systematic review and meta-analysis

(2011) A. K. Ngugi et al.   NEUROLOGY

Interleukin-1β Biosynthesis Inhibition Reduces Acute Seizures and Drug Resistant Chronic Epileptic Activity in Mice

(2011) Mattia Maroso et al.   Neurotherapeutics

Revisiting AMPA Receptors as an Antiepileptic Drug Target

(2011) Michael A. Rogawski   Epilepsy Currents

Progress report on new antiepileptic drugs: A summary of the Tenth Eilat Conference (EILAT X)

(2010) Meir Bialer et al.   EPILEPSY RESEARCH

Adjunctive brivaracetam for refractory partial-onset seizures: A randomized, controlled trial

(2010) J. A. French et al.   NEUROLOGY

The Efficacy of the AMPA Receptor Antagonist NS1209 and Lidocaine in Nerve Injury Pain: A Randomized, Double-Blind, Placebo-Controlled, Three-Way Crossover Study

(2009) Lise Gormsen et al.   ANESTHESIA AND ANALGESIA

Antiepileptic Drug-Induced Cognitive Adverse Effects

(2009) Marco Mula et al.   CNS DRUGS

What is the promise of new antiepileptic drugs in status epilepticus? Focus on brivaracetam, carisbamate, lacosamide, NS-1209, and topiramate

(2009) Emilio Perucca   EPILEPSIA

Definition of drug resistant epilepsy: Consensus proposal by the ad hoc Task Force of the ILAE Commission on Therapeutic Strategies

(2009) Patrick Kwan et al.   EPILEPSIA

Placebo-corrected efficacy of modern antiepileptic drugs for refractory epilepsy: Systematic review and meta-analysis

(2009) Stefan Beyenburg et al.   EPILEPSIA

Lamotrigine inhibits postsynaptic AMPA receptor and glutamate release in the dentate gyrus

(2008) Chun-Yao Lee et al.   EPILEPSIA

The global burden and stigma of epilepsy

(2008) Hanneke M. de Boer et al.   EPILEPSY & BEHAVIOR

Interleukin Converting Enzyme inhibition impairs kindling epileptogenesis in rats by blocking astrocytic IL-1β production

(2008) Teresa Ravizza et al.   NEUROBIOLOGY OF DISEASE

Inhibitory effects of the antiepileptic drug ethosuximide on G protein-activated inwardly rectifying K+ channels

(2008) Toru Kobayashi et al.   NEUROPHARMACOLOGY

The oral absorption of phospholipid prodrugs: In vivo and in vitro mechanistic investigation of trafficking of a lecithin-valproic acid conjugate following oral administration

(2007) Arik Dahan et al.   JOURNAL OF CONTROLLED RELEASE