Safety profile of two novel antiepileptic agents approved for the treatment of refractory partial seizures: ezogabine (retigabine) and perampanel

Safety and tolerability of perampanel: a review of clinical trial data

(2013) J. M. Serratosa et al.   ACTA NEUROLOGICA SCANDINAVICA

Ezogabine: A Novel Antiepileptic for Adjunctive Treatment of Partial-Onset Seizures

(2013) Celene M. Amabile et al.   PHARMACOTHERAPY

Perampanel

(2012) Greg L. Plosker   CNS DRUGS

Evaluation of adjunctive perampanel in patients with refractory partial-onset seizures: Results of randomized global phase III study 305

(2012) Jacqueline A. French et al.   EPILEPSIA

Perampanel, a selective, noncompetitive α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor antagonist, as adjunctive therapy for refractory partial-onset seizures: Interim results from phase III, extension study 307

(2012) Gregory L. Krauss et al.   EPILEPSIA

The urinary safety profile and secondary renal effects of retigabine (ezogabine): A first-in-class antiepileptic drug that targets KCNQ (Kv7) potassium channels

(2012) Neil Brickel et al.   EPILEPSIA

Safety and efficacy of ezogabine (retigabine) in adults with refractory partial-onset seizures: Interim results from two ongoing open-label studies

(2012) Antonio Gil-Nagel et al.   EPILEPSY RESEARCH

Adjunctive perampanel for refractory partial-onset seizures: Randomized phase III study 304

(2012) J. A. French et al.   NEUROLOGY

Randomized phase III study 306: Adjunctive perampanel for refractory partial-onset seizures

(2012) G. L. Krauss et al.   NEUROLOGY

Tolerability and safety of perampanel: two randomized dose-escalation studies

(2011) G. L. Krauss et al.   ACTA NEUROLOGICA SCANDINAVICA

Randomized, double-blind, placebo-controlled trial of ezogabine (retigabine) in partial epilepsy

(2011) J. A. French et al.   NEUROLOGY

Ezogabine: A New Angle On Potassium Gates

(2011) Edward Faught   Epilepsy Currents

Revisiting AMPA Receptors as an Antiepileptic Drug Target

(2011) Michael A. Rogawski   Epilepsy Currents

Treatment options for refractory and difficult to treat seizures: focus on vigabatrin

(2011) Justin Tolman et al.   Therapeutics and Clinical Risk Management

Voltage-gated K+ channels sensitive to stromatoxin-1 regulate myogenic and neurogenic contractions of rat urinary bladder smooth muscle

(2010) Muyan Chen et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Functional effects of the KCNQ modulators retigabine and XE991 in the rat urinary bladder

(2010) Frederik Rode et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Isoform-specific Prolongation of Kv7 (KCNQ) Potassium Channel Opening Mediated by New Molecular Determinants for Drug-Channel Interactions

(2010) Zhaobing Gao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Efficacy and safety of adjunctive ezogabine (retigabine) in refractory partial epilepsy

(2010) M. J. Brodie et al.   NEUROLOGY