Drug absorption, distribution, metabolism and excretion considerations in critically ill adults

Factors Predisposing to Coma and Delirium

(2013) Yoanna Skrobik et al.   CRITICAL CARE MEDICINE

Introduction to Drug Pharmacokinetics in the Critically III Patient

(2012) Brian S. Smith et al.   CHEST

Sedation for Critically Ill or Injured Adults in the Intensive Care Unit

(2012) Derek J. Roberts et al.   DRUGS

Negative-pressure wound therapy for critically ill adults with open abdominal wounds

(2012) Derek J. Roberts et al.   Journal of Trauma and Acute Care Surgery

Rewarming after hypothermia after cardiac arrest shifts the inflammatory balance*

(2011) Laurens L. A. Bisschops et al.   CRITICAL CARE MEDICINE

The Effect of Critical Illness on Drug Distribution

(2011) Daniel Gonzalez et al.   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

The effect of therapeutic hypothermia on drug metabolism and response: cellular mechanisms to organ function

(2011) Jiangquan Zhou et al.   Expert Opinion on Drug Metabolism & Toxicology

Pharmacokinetics of a loading dose of amikacin in septic patients undergoing continuous renal replacement therapy

(2011) Fabio Silvio Taccone et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Effects of Hypothermia on Pharmacokinetics and Pharmacodynamics

(2010) Marcel P.H. van den Broek et al.   CLINICAL PHARMACOKINETICS

Common drug interactions leading to adverse drug events in the intensive care unit: Management and pharmacokinetic considerations

(2010) John Papadopoulos et al.   CRITICAL CARE MEDICINE

Mild Hypothermia Alters Midazolam Pharmacokinetics in Normal Healthy Volunteers

(2010) D. Hostler et al.   DRUG METABOLISM AND DISPOSITION

Aminoglycoside Pharmacokinetic Parameters in Neurocritical Care Patients Undergoing Induced Hypothermia

(2010) Jessica M Mercer et al.   PHARMACOTHERAPY

The effect of induced hypothermia on respiratory parameters in mechanically ventilated patients

(2010) Hamid Aslami et al.   RESUSCITATION

Capillary leakage in post-cardiac arrest survivors during therapeutic hypothermia - a prospective, randomised study

(2010) Bård E Heradstveit et al.   Scandinavian Journal of Trauma Resuscitation & Emergency Medicine

Vasopressin decreases intestinal mucosal perfusion: a clinical study on cardiac surgery patients in vasodilatory shock

(2009) A. NYGREN et al.   ACTA ANAESTHESIOLOGICA SCANDINAVICA

Systematic review: impaired drug absorption related to the co-administration of antisecretory therapy

(2009) E. LAHNER et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Population Pharmacokinetics of Meropenem in Critically Ill Patients Undergoing Continuous Renal Replacement Therapy

(2009) Arantxazu Isla et al.   CLINICAL PHARMACOKINETICS

Augmented Renal Clearance

(2009) Andrew A. Udy et al.   CLINICAL PHARMACOKINETICS

Effect of acute inflammatory brain injury on accumulation of morphine and morphine 3- and 6-glucuronide in the human brain*

(2009) Derek J. Roberts et al.   CRITICAL CARE MEDICINE

Pharmacokinetic issues for antibiotics in the critically ill patient

(2009) Jason A. Roberts et al.   CRITICAL CARE MEDICINE

Principles of antibacterial dosing in continuous renal replacement therapy

(2009) Gordon Choi et al.   CRITICAL CARE MEDICINE

Risk of Adverse Clinical Outcomes with Concomitant Use of Clopidogrel and Proton Pump Inhibitors Following Percutaneous Coronary Intervention

(2009) Ekta Gupta et al.   DIGESTIVE DISEASES AND SCIENCES

Mini-series: II. Clinical aspects. Clinically relevant CYP450-mediated drug interactions in the ICU

(2009) Isabel Spriet et al.   INTENSIVE CARE MEDICINE

Effects of propofol and dexmedetomidine on indocyanine green elimination assessed with LİMON to patients with early septic shock: A pilot study

(2009) Dilek Memiş et al.   JOURNAL OF CRITICAL CARE

Regulation of Drug-Metabolizing Enzymes and Transporters in Infection, Inflammation, and Cancer

(2008) E. T. Morgan et al.   DRUG METABOLISM AND DISPOSITION

A critical overview of the influence of inflammation and infection on P-glycoprotein expression and activity in the brain

(2008) Derek J Roberts et al.   Expert Opinion on Drug Metabolism & Toxicology

Evaluation of area under the inhibitory curve (AUIC) and time above the minimum inhibitory concentration (T>MIC) as predictors of outcome for cefepime and ceftazidime in serious bacterial infections

(2008) Peggy S. McKinnon et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Structure, function and regulation of P-glycoprotein and its clinical relevance in drug disposition

(2008) S.-F. Zhou   XENOBIOTICA