The effects of flavonoids on the ABC transporters: consequences for the pharmacokinetics of substrate drugs

Pharmacokinetic interaction study of sulphasalazine in healthy subjects and the impact of curcumin as an in vivo inhibitor of BCRP

(2012) Hiroyuki Kusuhara et al.   BRITISH JOURNAL OF PHARMACOLOGY

The Role of ABC and SLC Transporters in the Pharmacokinetics of Dietary and Herbal Phytochemicals and their Interactions with Xenobiotics

(2012) Yan Li et al.   CURRENT DRUG METABOLISM

In vitro and in vivo modulation of ABCG2 by functionalized aurones and structurally related analogs

(2011) Hong-May Sim et al.   BIOCHEMICAL PHARMACOLOGY

Flavonoid conjugates interact with organic anion transporters (OATs) and attenuate cytotoxicity of adefovir mediated by organic anion transporter 1 (OAT1/SLC22A6)

(2011) Chi Chun Wong et al.   BIOCHEMICAL PHARMACOLOGY

The sulfated conjugate of biochanin A is a substrate of breast cancer resistant protein (ABCG2)

(2011) Guohua An et al.   BIOPHARMACEUTICS & DRUG DISPOSITION

Modulation of P-glycoprotein-Mediated Anticancer Drug Accumulation, Cytotoxicity, and ATPase Activity by Flavonoid Interactions

(2011) Van Tran et al.   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL

5,7-Dimethoxyflavone and Multiple Flavonoids in Combination Alter the ABCG2-Mediated Tissue Distribution of Mitoxantrone in Mice

(2011) Guohua An et al.   PHARMACEUTICAL RESEARCH

Fruit juice inhibition of uptake transport: a new type of food-drug interaction

(2010) David G. Bailey   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

The Bioflavonoid Kaempferol Is an Abcg2 Substrate and Inhibits Abcg2-Mediated Quercetin Efflux

(2010) G. An et al.   DRUG METABOLISM AND DISPOSITION

Interactions of dietary phytochemicals with ABC transporters: possible implications for drug disposition and multidrug resistance in cancer

(2010) Yan Li et al.   DRUG METABOLISM REVIEWS

Membrane transporters in drug development

(2010)   NATURE REVIEWS DRUG DISCOVERY

Berry anthocyanins and anthocyanidins exhibit distinct affinities for the efflux transporters BCRP and MDR1

(2009) A Dreiseitel et al.   BRITISH JOURNAL OF PHARMACOLOGY

Drug transporters: Gatekeepers controlling access of xenobiotics to the cellular interior

(2009) Lesley A. Stanley et al.   DRUG METABOLISM REVIEWS

Short-term effect of quercetin on the pharmacokinetics of fexofenadine, a substrate of P-glycoprotein, in healthy volunteers

(2009) Kyoung-Ah Kim et al.   EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY

Interactions between the flavonoid biochanin A and P-glycoprotein substrates in rats: In vitro and in vivo

(2009) Shuzhong Zhang et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Modulation of the activity of ABC transporters (P-glycoprotein, MRP2, BCRP) by flavonoids and drug response

(2009) Ana I. Alvarez et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

ABC transporters: the power to change

(2009) Douglas C. Rees et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

A comparative study of the effects of quercetin and its glucuronide and sulfate metabolites on human neutrophil function in vitro

(2008) Sunita Suri et al.   BIOCHEMICAL PHARMACOLOGY

Role of ATP-Binding Cassette (ABC) Transporters in Interactions Between Natural Products and Drugs

(2008) Adorjan Aszalos   CURRENT DRUG METABOLISM

Substrate-Dependent Breast Cancer Resistance Protein (Bcrp1/Abcg2)-Mediated Interactions: Consideration of Multiple Binding Sites in in Vitro Assay Design

(2008) N. Giri et al.   DRUG METABOLISM AND DISPOSITION

Human cytochromes P450 in the metabolism of drugs: new molecular models of enzyme–substrate interactions

(2008) David FV Lewis et al.   Expert Opinion on Drug Metabolism & Toxicology

Effect of Grapefruit Juice, Naringin, Naringenin, and Bergamottin on the Intestinal Carrier-Mediated Transport of Talinolol in Rats

(2008) Whocely Victor de Castro et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Pre-clinical evidence for altered absorption and biliary excretion of irinotecan (CPT-11) in combination with quercetin: Possible contribution of P-glycoprotein

(2008) Tripta Bansal et al.   LIFE SCIENCES

Concentration-Dependent Effect of Naringin on Intestinal Absorption of β1-Adrenoceptor Antagonist Talinolol Mediated by P-Glycoprotein and Organic Anion Transporting Polypeptide (Oatp)

(2008) Yoshiyuki Shirasaka et al.   PHARMACEUTICAL RESEARCH

Curcumin Inhibits the Activity of ABCG2/BCRP1, a Multidrug Resistance-Linked ABC Drug Transporter in Mice

(2008) Suneet Shukla et al.   PHARMACEUTICAL RESEARCH