Combination therapy of Western drugs and herbal medicines: recent advances in understanding interactions involving metabolism and efflux

Role of transporters in drug interactions

(2011) Hyo-Kyung Han   ARCHIVES OF PHARMACAL RESEARCH

Inhibitory Effects of Commonly Used Herbal Extracts on UDP-Glucuronosyltransferase 1A4, 1A6, and 1A9 Enzyme Activities

(2011) M.-E. F. Mohamed et al.   DRUG METABOLISM AND DISPOSITION

Danshen extract does not alter pharmacokinetics of docetaxel and clopidogrel, reflecting its negligible potential in P-glycoprotein- and cytochrome P4503A-mediated herb–drug interactions

(2011) Joo Hyun Lee et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

The effect of Compound Danshen Dripping Pills, a Chinese herb medicine, on the pharmacokinetics and pharmacodynamics of warfarin in rats

(2011) Yang Chu et al.   JOURNAL OF ETHNOPHARMACOLOGY

Role for monoaminergic systems in the antidepressant-like effect of ethanol extracts from Hemerocallis citrina

(2011) Lan Gu et al.   JOURNAL OF ETHNOPHARMACOLOGY

Investigation of cytochrome P450 1A2 and 3A inhibitory properties of Danshen tincture

(2011) Xin Wang et al.   PHYTOMEDICINE

Ginkgo biloba extract attenuates warfarin-mediated anticoagulation through induction of hepatic cytochrome P450 enzymes by bilobalide in mice

(2011) Yuko Taki et al.   PHYTOMEDICINE

Investigation of UDP-glucuronosyltransferases (UGTs) Inhibitory Properties of Carvacrol

(2011) Rui-Hua Dong et al.   PHYTOTHERAPY RESEARCH

Imatinib and Panax Ginseng: A Potential Interaction Resulting in Liver Toxicity

(2010) Naveen Bilgi et al.   ANNALS OF PHARMACOTHERAPY

Chemical and Pharmacological Chaperones: Application for Recombinant Protein Production and Protein Folding Diseases

(2010) Rahul S. Rajan et al.   CURRENT MEDICINAL CHEMISTRY

Effects of Ginkgo biloba extracts on diazepam metabolism: a pharmacokinetic study in healthy Chinese male subjects

(2010) Xiao-Cong Zuo et al.   EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY

In vitro interactions between aged garlic extract and drugs used for the treatment of cardiovascular and diabetic patients

(2010) Katja Berginc et al.   EUROPEAN JOURNAL OF NUTRITION

Garlic extract induces intestinal P-glycoprotein, but exhibits no effect on intestinal and hepatic CYP3A4 in humans

(2010) Jacek Hajda et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Relaxation Acupressure Reduces Persistent Cancer-Related Fatigue

(2010) Suzanna M. Zick et al.   Evidence-based Complementary and Alternative Medicine

Effects of herbal products on the metabolism and transport of anticancer agents

(2010) Shu-Ming He et al.   Expert Opinion on Drug Metabolism & Toxicology

Drug interaction between St John’s wort and zolpidem in healthy subjects

(2010) Y. Hojo et al.   JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS

In vitro modulatory effects of Andrographis paniculata, Centella asiatica and Orthosiphon stamineus on cytochrome P450 2C19 (CYP2C19)

(2010) Yan Pan et al.   JOURNAL OF ETHNOPHARMACOLOGY

Use of Herbal Products and Potential Interactions in Patients With Cardiovascular Diseases

(2010) Ara Tachjian et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Drug Interaction Between Complementary Herbal Medicines and Gefitinib

(2010) Sung-Wook Hwang et al.   Journal of Thoracic Oncology

A pharmacodynamic–pharmacokinetic (PD–PK) study on the effects of Danshen (Salvia miltiorrhiza) on midazolam, a model CYP3A probe substrate, in the rat

(2010) Xin Wang et al.   PHYTOMEDICINE

Major tanshinones of Danshen (Salvia miltiorrhiza) exhibit different modes of inhibition on human CYP1A2, CYP2C9, CYP2E1 and CYP3A4 activities in vitro

(2010) Xin Wang et al.   PHYTOMEDICINE

Anxiolytic effects of fractions obtained from Passiflora incarnata L. in the elevated plus maze in mice

(2010) C. Sampath et al.   PHYTOTHERAPY RESEARCH

Pregnane X receptor-mediated induction of Cyp3a by black cohosh

(2010) Xiaoyan Pang et al.   XENOBIOTICA

Herb–Drug Interactions with St John’s Wort (Hypericum perforatum): an Update on Clinical Observations

(2009) Francesca Borrelli et al.   AAPS Journal

Aloe-induced hypokalemia in a patient with breast cancer during chemotherapy

(2009) Z. Baretta et al.   ANNALS OF ONCOLOGY

Time-dependent inhibition (TDI) of CYP3A4 and CYP2C9 by noscapine potentially explains clinical noscapine-warfarin interaction

(2009) Zhong-Ze Fang et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Herb–drug interaction of silymarin or silibinin on the pharmacokinetics of trazodone in rats

(2009) Jen-Chih Chang et al.   CHEMICO-BIOLOGICAL INTERACTIONS

The potential for interaction of hydrochlorothiazide with garlic in rats

(2009) Syed Mohammed Basheeruddin Asdaq et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Effects of Short-Term and Long-Term Pretreatment of Schisandra Lignans on Regulating Hepatic and Intestinal CYP3A in Rats

(2009) L. Lai et al.   DRUG METABOLISM AND DISPOSITION

Interactions Between Herbal Medicines and Prescribed Drugs

(2009) Angelo A. Izzo et al.   DRUGS

Scientific and Regulatory Perspectives on Metabolizing Enzyme−Transporter Interplay and Its Role in Drug Interactions: Challenges in Predicting Drug Interactions†

(2009) Lei Zhang et al.   MOLECULAR PHARMACEUTICS

Interactions ofValeriana officinalisL. andPassiflora incarnataL. in a patient treated with lorazepam

(2009) María Consuelo Carrasco et al.   PHYTOTHERAPY RESEARCH

Herb-Drug Interactions:In VivoandIn VitroEffect of Shenmai Injection, a Herbal Preparation, on the Metabolic Activities of Hepatic Cytochrome P450 3A1/2, 2C6, 1A2, and 2E1 in Rats

(2009) Chun-hua Xia et al.   PLANTA MEDICA

Lifestyle habits as a contributor to anti-cancer treatment failure

(2008) Floris A. de Jong et al.   EUROPEAN JOURNAL OF CANCER

No clinically relevant CYP3A induction after St. John’s wort with low hyperforin content in healthy volunteers

(2008) Silke C. Mueller et al.   EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY

Influence of fruit juices on drug disposition: discrepancies betweenin vitroand clinical studies

(2008) Dora Farkas et al.   Expert Opinion on Drug Metabolism & Toxicology

Recurrent relapses of depression in a patient established on sertraline after taking herbal medicinal mixtures – a herb–drug interaction?

(2008) KPRC Prasad et al.   JOURNAL OF PSYCHOPHARMACOLOGY

Pre-clinical evidence for altered absorption and biliary excretion of irinotecan (CPT-11) in combination with quercetin: Possible contribution of P-glycoprotein

(2008) Tripta Bansal et al.   LIFE SCIENCES

Gauging the clinical significance of P‐glycoprotein‐mediated herb‐drug interactions: Comparative effects of St. John's wort, Echinacea, clarithromycin, and rifampin on digoxin pharmacokinetics

(2008) Bill J. Gurley et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Herbal medicine and epilepsy: Proconvulsive effects and interactions with antiepileptic drugs

(2007) Noah Samuels et al.   EPILEPSIA

Some commonly fed herbs and other functional foods in equine nutrition: A review

(2007) Carey A. Williams et al.   VETERINARY JOURNAL

Unwanted pregnancy on self-medication with St John's wort despite hormonal contraception

(2003) Ute I. Schwarz et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY