Role of microRNAs in the regulation of drug metabolizing and transporting genes and the response to environmental toxicants

PHASE II DRUG METABOLIZING ENZYMES

(2012) Petra Jancova et al.   BIOMEDICAL PAPERS-OLOMOUC

Nrf2: control of sensitivity to carcinogens

(2011) Stephen L. Slocum et al.   ARCHIVES OF TOXICOLOGY

PPARs are a unique set of fatty acid regulated transcription factors controlling both lipid metabolism and inflammation

(2011) Tamas Varga et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

MiR-28 regulates Nrf2 expression through a Keap1-independent mechanism

(2011) Muhua Yang et al.   BREAST CANCER RESEARCH AND TREATMENT

Genetic Variation in an miRNA-1827 Binding Site in MYCL1 Alters Susceptibility to Small-Cell Lung Cancer

(2011) F. Xiong et al.   CANCER RESEARCH

Metabolism and Biomarkers of Heterocyclic Aromatic Amines in Molecular Epidemiology Studies: Lessons Learned from Aromatic Amines

(2011) Robert J. Turesky et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Reduced miR-128 in Breast Tumor-Initiating Cells Induces Chemotherapeutic Resistance via Bmi-1 and ABCC5

(2011) Y. Zhu et al.   CLINICAL CANCER RESEARCH

Clinically Relevant Genetic Variations in Drug Metabolizing Enzymes

(2011) Navin Pinto et al.   CURRENT DRUG METABOLISM

Glutathione transferases: a structural perspective

(2011) Aaron Oakley   DRUG METABOLISM REVIEWS

Silencing of miR-124 induces neuroblastoma SK-N-SH cell differentiation, cell cycle arrest and apoptosis through promoting AHR

(2011) Tsui-Chin Huang et al.   FEBS LETTERS

MicroRNA 506 regulates expression of PPAR alpha in hydroxycamptothecin-resistant human colon cancer cells

(2011) Jin Lu Tong et al.   FEBS LETTERS

MicroRNA-421 functions as an oncogenic miRNA in biliary tract cancer through down-regulating farnesoid X receptor expression

(2011) Xiang-yu Zhong et al.   GENE

Unusually effective microRNA targeting within repeat-rich coding regions of mammalian mRNAs

(2011) M. Schnall-Levin et al.   GENOME RESEARCH

Circulating microRNAs as potential markers of human drug-induced liver injury

(2011) Philip J. Starkey Lewis et al.   HEPATOLOGY

Adenosine triphosphate-binding cassette transporter genes up-regulation in untreated hepatocellular carcinoma is mediated by cellular microRNAs

(2011) Florie Borel et al.   HEPATOLOGY

miR-200a Regulates Nrf2 Activation by TargetingKeap1mRNA in Breast Cancer Cells

(2011) Gabriel Eades et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Genetic polymorphisms and microRNAs: new direction in molecular epidemiology of solid cancer

(2011) Ondrej Slaby et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Discovering environmental causes of disease

(2011) Stephen M Rappaport   JOURNAL OF EPIDEMIOLOGY AND COMMUNITY HEALTH

Increased expression of miR-34a and miR-93 in rat liver during aging, and their impact on the expression of Mgst1 and Sirt1

(2011) Na Li et al.   MECHANISMS OF AGEING AND DEVELOPMENT

MicroRNA hsa-miR-613 Targets the HumanLXRα Gene and Mediates a Feedback Loop of LXRα Autoregulation

(2011) Zhimin Ou et al.   MOLECULAR ENDOCRINOLOGY

Down-Regulation of ATP-Binding Cassette C2 Protein Expression in HepG2 Cells after Rifampicin Treatment Is Mediated by MicroRNA-379

(2011) S. Haenisch et al.   MOLECULAR PHARMACOLOGY

Epigenetic regulation of microRNAs in cancer: An integrated review of literature

(2011) Tanja Kunej et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Environmental chemicals and microRNAs

(2011) Lifang Hou et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Functional relevance of miRNA* sequences in human disease

(2011) Mihir K. Bhayani et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

PPARα Is Regulated by miR-21 and miR-27b in Human Liver

(2011) Katsuhiko Kida et al.   PHARMACEUTICAL RESEARCH

Tissue-specific function of farnesoid X receptor in liver and intestine

(2011) Yan Zhu et al.   PHARMACOLOGICAL RESEARCH

MicroRNA-21 targets peroxisome proliferators-activated receptor-  in an autoregulatory loop to modulate flow-induced endothelial inflammation

(2011) J. Zhou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Toxicological Implications of Modulation of Gene Expression by MicroRNAs

(2011) Tsuyoshi Yokoi et al.   TOXICOLOGICAL SCIENCES

Involvement of MicroRNAs in Dioxin-Induced Liver Damage in the Mouse

(2011) Wataru Yoshioka et al.   TOXICOLOGICAL SCIENCES

MicroRNA pharmacogenomics: Post-transcriptional regulation of drug response

(2011) Jakob Lewin Rukov et al.   TRENDS IN MOLECULAR MEDICINE

Regulation of mRNA Translation and Stability by microRNAs

(2010) Marc Robert Fabian et al.   Annual Review of Biochemistry

miR-27a is a negative regulator of adipocyte differentiation via suppressing PPARγ expression

(2010) Sang Yun Kim et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

microRNA miR-144 modulates oxidative stress tolerance and associates with anemia severity in sickle cell disease

(2010) C. Sangokoya et al.   BLOOD

Epigenetic Changes Induced by Air Toxics: Formaldehyde Exposure Alters miRNA Expression Profiles in Human Lung Cells

(2010) Julia E. Rager et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

CYP2E1 and risk of chemically mediated cancers

(2010) Dimitrios T Trafalis et al.   Expert Opinion on Drug Metabolism & Toxicology

MiR-27a modulates MDR1/P-glycoprotein expression by targeting HIPK2 in human ovarian cancer cells

(2010) Zhimin Li et al.   GYNECOLOGIC ONCOLOGY

Alterations of microRNAs and their targets are associated with acquired resistance of MCF-7 breast cancer cells to cisplatin

(2010) Igor P. Pogribny et al.   INTERNATIONAL JOURNAL OF CANCER

MicroRNA-27b Contributes to Lipopolysaccharide-mediated Peroxisome Proliferator-activated Receptor γ (PPARγ) mRNA Destabilization

(2010) Carla Jennewein et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

miR-130 Suppresses Adipogenesis by Inhibiting Peroxisome Proliferator-Activated Receptor   Expression

(2010) E. K. Lee et al.   MOLECULAR AND CELLULAR BIOLOGY

Mammalian microRNAs predominantly act to decrease target mRNA levels

(2010) Huili Guo et al.   NATURE

Targeting microRNAs in cancer: rationale, strategies and challenges

(2010) Ramiro Garzon et al.   NATURE REVIEWS DRUG DISCOVERY

Functional Genetic Variants in the 3′-Untranslated Region of Sulfotransferase Isoform 1A1 (SULT1A1) and Their Effect on Enzymatic Activity

(2010) Xinfeng Yu et al.   TOXICOLOGICAL SCIENCES

miR-22 functions as a micro-oncogene in transformed human bronchial epithelial cells induced by anti-benzo[a]pyrene-7,8-diol-9,10-epoxide

(2010) Linhua Liu et al.   TOXICOLOGY IN VITRO

Human CYP2E1 is regulated by miR-378

(2009) Takuya Mohri et al.   BIOCHEMICAL PHARMACOLOGY

Involvement of miR-326 in chemotherapy resistance of breast cancer through modulating expression of multidrug resistance-associated protein 1

(2009) Zhongxing Liang et al.   BIOCHEMICAL PHARMACOLOGY

Plasma miR-208 as a Biomarker of Myocardial Injury

(2009) X. Ji et al.   CLINICAL CHEMISTRY

Plasma MicroRNAs as Sensitive and Specific Biomarkers of Tissue Injury

(2009) O. F. Laterza et al.   CLINICAL CHEMISTRY

Role of microRNAs in the regulation of drug metabolism and disposition

(2009) Ai-Ming Yu   Expert Opinion on Drug Metabolism & Toxicology

The complexities of microRNA regulation: mirandering around the rules

(2009) Kimberly Breving et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Effect of miRNA-10b in regulating cellular steatosis level by targeting PPAR-α expression, a novel mechanism for the pathogenesis of NAFLD

(2009) Lin Zheng et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

miR-22 Inhibits Estrogen Signaling by Directly Targeting the Estrogen Receptor   mRNA

(2009) D. P. Pandey et al.   MOLECULAR AND CELLULAR BIOLOGY

The Role of miR-206 in the Epidermal Growth Factor (EGF) Induced Repression of Estrogen Receptor-α (ERα) Signaling and a Luminal Phenotype in MCF-7 Breast Cancer Cells

(2009) Brian D. Adams et al.   MOLECULAR ENDOCRINOLOGY

MicroRNA-328 Negatively Regulates the Expression of Breast Cancer Resistance Protein (BCRP/ABCG2) in Human Cancer Cells

(2009) Y.-Z. Pan et al.   MOLECULAR PHARMACOLOGY

Loss of miR-122 expression in liver cancer correlates with suppression of the hepatic phenotype and gain of metastatic properties

(2009) C Coulouarn et al.   ONCOGENE

MicroRNA polymorphisms: the future of pharmacogenomics, molecular epidemiology and individualized medicine

(2009) Prasun J Mishra et al.   PHARMACOGENOMICS

Circulating microRNAs, potential biomarkers for drug-induced liver injury

(2009) K. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Role of MicroRNA miR-27a and miR-451 in the regulation of MDR1/P-glycoprotein expression in human cancer cells

(2008) Hua Zhu et al.   BIOCHEMICAL PHARMACOLOGY

Xenobiotic-Activated Receptors: From Transcription to Drug Metabolism to Disease

(2008) Qiang Ma   CHEMICAL RESEARCH IN TOXICOLOGY

Epigenetic Regulation of Genes Encoding Drug-Metabolizing Enzymes and Transporters; DNA Methylation and Other Mechanisms

(2008) Ichiro Ieiri et al.   CURRENT DRUG METABOLISM

RDX Induces Aberrant Expression of MicroRNAs in Mouse Brain and Liver

(2008) Baohong Zhang et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Most mammalian mRNAs are conserved targets of microRNAs

(2008) R. C. Friedman et al.   GENOME RESEARCH

Post-transcriptional Regulation of Human Pregnane X Receptor by Micro-RNA Affects the Expression of Cytochrome P450 3A4

(2008) Shingo Takagi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MicroRNA-221/222 Negatively Regulates Estrogen Receptorα and Is Associated with Tamoxifen Resistance in Breast Cancer

(2008) Jian-Jun Zhao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulation of ABCG2 Expression at the 3' Untranslated Region of Its mRNA through Modulation of Transcript Stability and Protein Translation by a Putative MicroRNA in the S1 Colon Cancer Cell Line

(2008) K. K. W. To et al.   MOLECULAR AND CELLULAR BIOLOGY

Involvement of microRNA-451 in resistance of the MCF-7 breast cancer cells to chemotherapeutic drug doxorubicin

(2008) O. Kovalchuk et al.   MOLECULAR CANCER THERAPEUTICS

Environmental exposure measurement in cancer epidemiology

(2008) C. P. Wild   MUTAGENESIS

Widespread changes in protein synthesis induced by microRNAs

(2008) Matthias Selbach et al.   NATURE

MicroRNAs to Nanog, Oct4 and Sox2 coding regions modulate embryonic stem cell differentiation

(2008) Yvonne Tay et al.   NATURE

p16INK4a Translation Suppressed by miR-24

(2008) Ashish Lal et al.   PLoS One

MicroRNA-373 induces expression of genes with complementary promoter sequences

(2008) R. F. Place et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

miR-148 targets human DNMT3b protein coding region

(2008) A. M. Duursma et al.   RNA