The effects of obesity on drug pharmacokinetics in humans

Estimating the Glomerular Filtration Rate in Obese Adult Patients for Drug Dosing

(2010) Manjunath P. Pai   ADVANCES IN CHRONIC KIDNEY DISEASE

Pharmacogenetics and human genetic polymorphisms

(2010) Ann K. Daly   BIOCHEMICAL JOURNAL

Effect of Obesity on the Pharmacokinetics of Drugs in Humans

(2010) Michael J. Hanley et al.   CLINICAL PHARMACOKINETICS

Predictive Performance of the ‘Minto’ Remifentanil Pharmacokinetic Parameter Set in Morbidly Obese Patients Ensuing from a New Method for Calculating Lean Body Mass

(2010) Luca La Colla et al.   CLINICAL PHARMACOKINETICS

Perioperative pharmacology in morbid obesity

(2010) Hendrikus JM Lemmens   Current Opinion in Anesthesiology

Renal clearance in drug discovery and development: molecular descriptors, drug transporters and disease state

(2010) Bo Feng et al.   Expert Opinion on Drug Metabolism & Toxicology

The Meaning and Measurement of Lean Body Mass

(2010) Ronenn Roubenoff et al.   NUTRITION REVIEWS

Biochemical and analytical development of the CIME cocktail for drug fate assessment in humans

(2010) Orianne Videau et al.   RAPID COMMUNICATIONS IN MASS SPECTROMETRY

Prediction of Hepatic Clearance in Human From In Vitro Data for Successful Drug Development

(2009) Masato Chiba et al.   AAPS Journal

Estimation of creatinine clearance in morbidly obese patients

(2009) Jasmina A. Demirovic et al.   AMERICAN JOURNAL OF HEALTH-SYSTEM PHARMACY

To scale or not to scale: the principles of dose extrapolation

(2009) Vijay Sharma et al.   BRITISH JOURNAL OF PHARMACOLOGY

A Universal Formula Based on Cystatin C to Perform Individual Dosing of Carboplatin in Normal Weight, Underweight, and Obese Patients

(2009) A. Schmitt et al.   CLINICAL CANCER RESEARCH

Informative study designs to identify true parameter–covariate relationships

(2009) Phey Yen Han et al.   JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS

Measured GFR as a Confirmatory Test for Estimated GFR

(2009) L. A. Stevens et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Human Organ/Tissue Growth Algorithms that Include Obese Individuals and Black/White Population Organ Weight Similarities from Autopsy Data

(2009) John F. Young et al.   JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES

Allometric scaling of clearance in dogs

(2009) M. MARTINEZ et al.   JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS

Pharmacogenetics of Membrane Transporters: An Update on Current Approaches

(2009) Tristan M. Sissung et al.   MOLECULAR BIOTECHNOLOGY

Expert Panel on Weight Loss Surgery: Executive Report Update

(2009) George L. Blackburn et al.   Obesity

Encouraging the Move Towards Predictive Population Models for the Obese Using Propofol as a Motivating Example

(2009) Sarah C. McLeay et al.   PHARMACEUTICAL RESEARCH

Roux-en-Y gastric bypass reverses renal glomerular but not tubular abnormalities in excessively obese diabetics

(2009) Jabbar Saliba et al.   SURGERY

Breast cancer adjuvant chemotherapy dosing in obese patients

(2008) Christopher G. Greenman et al.   CANCER

Carboplatin dosing in overweight and obese patients with normal renal function, does weight matter?

(2008) Corine Ekhart et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Obesity-induced glomerular hyperfiltration: its involvement in the pathogenesis of tubular sodium reabsorption

(2008) A. Chagnac et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Role of lean body mass for estimation of glomerular filtration rate in patients with chronic kidney disease with various body mass indices

(2008) Sehmus Ozmen et al.   SCANDINAVIAN JOURNAL OF UROLOGY AND NEPHROLOGY