Drug-induced liver injury: a summary of recent advances

Drug-Induced Hepatitis and Lupus during Infliximab Treatment for Psoriasis: Case Report and Literature Review

(2015) Yves Poulin et al.   JOURNAL OF CUTANEOUS MEDICINE AND SURGERY

Gone (From the Physicians’ Desk Reference ) But Not Forgotten: Propylthiouracil-Associated Hepatic Failure: A Call for Liver Test Monitoring

(2015) Jennifer Primeggia et al.   JOURNAL OF THE NATIONAL MEDICAL ASSOCIATION

Genetic Polymorphisms of Cytochrome P450 and Glutathione S-transferase Associated with Antituberculosis Drug-induced Hepatotoxicity in Chinese Tuberculosis Patients

(2013) T Wang et al.   JOURNAL OF INTERNATIONAL MEDICAL RESEARCH

Incidence and risk factors of severe adverse events with nevirapine-based antiretroviral therapy in HIV-infected women. MTCT-Plus program, Abidjan, Côte d'Ivoire

(2012) Patrick A Coffie et al.   BMC INFECTIOUS DISEASES

Amiodarone-induced liver cirrhosis and parkinsonism: a case report

(2011) S. Ishida et al.   CLINICAL NEUROPATHOLOGY

Use of Statins in Patients with Chronic Hepatitis C

(2011) Miranda R. Andrus et al.   SOUTHERN MEDICAL JOURNAL

The existence of a relationship between increased serum alanine aminotransferase levels detected in premarketing clinical trials and postmarketing published hepatotoxicity case reports

(2010) L. LLANOS et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Hepatotoxicity Due to Hydroxycut: A Case Series

(2010) Tse-Ling Fong et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

The Myth of Statin-Induced Hepatotoxicity

(2010) Ted Bader   AMERICAN JOURNAL OF GASTROENTEROLOGY

Single-Center Experience With Drug-Induced Liver Injury From India: Causes, Outcome, Prognosis and Predictors of Mortality

(2010) Harshad Devarbhavi et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Azithromycin-induced liver injury: Table 1

(2010) Alissa M. Lockwood et al.   AMERICAN JOURNAL OF HEALTH-SYSTEM PHARMACY

Toxic Hepatitis Induced by Gymnema sylvestre, a Natural Remedy for Type 2 Diabetes Mellitus

(2010) Arthur Shiyovich et al.   AMERICAN JOURNAL OF THE MEDICAL SCIENCES

Hepatotoxicity Fears Contribute to Underutilization of Statin Medications by Primary Care Physicians

(2010) Fadi S. Rzouq et al.   AMERICAN JOURNAL OF THE MEDICAL SCIENCES

Hepatotoxicity Associated with Metformin Therapy in Treatment of Type 2 Diabetes Mellitus with Nonalcoholic Fatty Liver Disease

(2010) Catherine J Cone et al.   ANNALS OF PHARMACOTHERAPY

Imatinib and Panax Ginseng: A Potential Interaction Resulting in Liver Toxicity

(2010) Naveen Bilgi et al.   ANNALS OF PHARMACOTHERAPY

Calcineurin Inhibitor-Related Cholestasis Complicating Lung Transplantation

(2010) Takahiro Oto et al.   ANNALS OF THORACIC SURGERY

Clinical and Toxicodynamic Evidence that High-Dose Pyrazinamide Is Not More Hepatotoxic than the Low Doses Currently Used

(2010) J. G. Pasipanodya et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Gastrointestinal and liver side effects of drugs in elderly patients

(2010) Konstantinos Triantafyllou et al.   BEST PRACTICE & RESEARCH IN CLINICAL GASTROENTEROLOGY

Trovafloxacin, a fluoroquinolone antibiotic with hepatotoxic potential, causes mitochondrial peroxynitrite stress in a mouse model of underlying mitochondrial dysfunction

(2010) Chin-Ju J. Hsiao et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Detective Work in Drug-Induced Liver Injury: Sometimes It Is All About Interviewing the Right Witness

(2010) A. Sidney Barritt et al.   Clinical Gastroenterology and Hepatology

Important Elements for the Diagnosis of Drug-Induced Liver Injury

(2010) Vijay K. Agarwal et al.   Clinical Gastroenterology and Hepatology

Challenges in Reintroducing Tuberculosis Medications after Hepatotoxicity

(2010) Jussi Saukkonen   CLINICAL INFECTIOUS DISEASES

Safety of 3 Different Reintroduction Regimens of Antituberculosis Drugs after Development of Antituberculosis Treatment–Induced Hepatotoxicity

(2010) Surendra K. Sharma et al.   CLINICAL INFECTIOUS DISEASES

Use of Pharmaco-Metabonomics for Early Prediction of Acetaminophen-Induced Hepatotoxicity in Humans

(2010) J H Winnike et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Cost minimization analysis comparing enteralN-acetylcysteine to intravenous acetylcysteine in the management of acute acetaminophen toxicity

(2010) Jay L. Martello et al.   CLINICAL TOXICOLOGY

Multiplying the serum aminotransferase by the acetaminophen concentration to predict toxicity following overdose

(2010) Marco L.A. Sivilotti et al.   CLINICAL TOXICOLOGY

Hepatotoxicity of Agents Used in the Management of Inflammatory Bowel Disease

(2010) Omar S. Khokhar et al.   DIGESTIVE DISEASES

Xanthine oxidase inhibition by allopurinol increasesin vitropyrazinamide-induced hepatotoxicity in HepG2 cells

(2010) Alma Tostmann et al.   DRUG AND CHEMICAL TOXICOLOGY

Drugs Associated with Hepatotoxicity and their Reporting Frequency of Liver Adverse Events in VigiBase™

(2010) Ayako Suzuki et al.   DRUG SAFETY

Protective effect of N-acetylcysteine on antituberculosis drug-induced hepatotoxicity

(2010) Shadi Baniasadi et al.   EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY

Predicting and preventing acute drug-induced liver injury: what's new in 2010?

(2010) Gordon Liss et al.   Expert Opinion on Drug Metabolism & Toxicology

Risk Factors for Idiosyncratic Drug-Induced Liver Injury

(2010) Naga Chalasani et al.   GASTROENTEROLOGY

Clinical syndromes and consequences of antiretroviral-related hepatotoxicity

(2010) Marina Núñez   HEPATOLOGY

Standardization of nomenclature and causality assessment in drug-induced liver injury: Summary of a clinical research workshop

(2010) Robert J. Fontana et al.   HEPATOLOGY

A role for the pregnane X receptor in flucloxacillin-induced liver injury

(2010) Elise Andrews et al.   HEPATOLOGY

Causality assessment in drug-induced liver injury using a structured expert opinion process: Comparison to the Roussel-Uclaf causality assessment method

(2010) Don C. Rockey et al.   HEPATOLOGY

Polymerase γ Gene POLG determines the risk of sodium valproate-induced liver toxicity

(2010) Joanna D. Stewart et al.   HEPATOLOGY

A meta-analysis of randomized trials for the treatment of nonalcoholic fatty liver disease

(2010) Giovanni Musso et al.   HEPATOLOGY

Drug-induced acute liver failure: Results of a U.S. multicenter, prospective study

(2010) Adrian Reuben et al.   HEPATOLOGY

Drug-induced autoimmune hepatitis: Clinical characteristics and prognosis

(2010) Einar Björnsson et al.   HEPATOLOGY

Unrecognized acetaminophen toxicity as a cause of indeterminate acute liver failure

(2010) Niraj Khandelwal et al.   HEPATOLOGY

Liver Toxicity After Switching or Simplifying to Nevirapine-Based Therapy Is Not Related to CD4 Cell Counts: Results of the TOSCANA Study

(2010) Antonio Antela et al.   HIV CLINICAL TRIALS

Nevirapine-associated hepatotoxicity was not predicted by CD4 count ≥250 cells/μL among women in Zambia, Thailand and Kenya

(2010) PJ Peters et al.   HIV MEDICINE

Infliximab-related hepatitis: discussion of a case and review of the literature

(2010) Stefano Mancini et al.   Internal and Emergency Medicine

Dissimilar Hepatotoxicity Profiles of Propylthiouracil and Methimazole in Children

(2010) Scott A. Rivkees et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Complementary and Alternative Medicine Use in Chronic Liver Disease Patients

(2010) Leah M. Ferrucci et al.   JOURNAL OF CLINICAL GASTROENTEROLOGY

Successful Treatment With Erlotinib After Gefitinib-Related Severe Hepatotoxicity

(2010) Masayuki Takeda et al.   JOURNAL OF CLINICAL ONCOLOGY

GSTT1 and GSTM1 gene deletions are not associated with hepatotoxicity caused by antitubercular drugs

(2010) S. Chatterjee et al.   JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS

Hepatotoxicity of alpha-methyldopa in pregnancy

(2010) R. Slim et al.   JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS

Aloe-induced Toxic Hepatitis

(2010) Ha Na Yang et al.   JOURNAL OF KOREAN MEDICAL SCIENCE

Clarifying metformin's role and risks in liver dysfunction

(2010) Carolyn C. Brackett   JOURNAL OF THE AMERICAN PHARMACISTS ASSOCIATION

Medical and psychiatric outcomes for patients transplanted for acetaminophen-induced acute liver failure: a case-control study

(2010) Constantine J. Karvellas et al.   LIVER INTERNATIONAL

Hepatotoxicity of khat chewing

(2010) Thierry Coton et al.   LIVER INTERNATIONAL

Liver disease and cirrhosis because of Khat chewing in UK Somali men: a case series

(2010) Camilla G. Peevers et al.   LIVER INTERNATIONAL

Acute liver failure due to antitubercular therapy: Strategy for antitubercular treatment before and after liver transplantation

(2010) Philippe Ichai et al.   LIVER TRANSPLANTATION

Successful treatment of two lung cancer patients with erlotinib following gefitinib-induced hepatotoxicity

(2010) Geoffrey Y. Ku et al.   LUNG CANCER

Statins in the Treatment of Dyslipidemia in the Presence of Elevated Liver Aminotransferase Levels: A Therapeutic Dilemma

(2010) Rossana M. Calderon et al.   MAYO CLINIC PROCEEDINGS

Letters to the editor

(2010) Gail Mahady et al.   MENOPAUSE-THE JOURNAL OF THE NORTH AMERICAN MENOPAUSE SOCIETY

Black cohosh and suspected hepatotoxicity

(2010) Rolf Teschke   MENOPAUSE-THE JOURNAL OF THE NORTH AMERICAN MENOPAUSE SOCIETY

Mechanisms of Pathogenesis in Drug Hepatotoxicity Putting the Stress on Mitochondria

(2010) D. P. Jones et al.   MOLECULAR INTERVENTIONS

A genome-wide study identifies HLA alleles associated with lumiracoxib-related liver injury

(2010) Jonathan B Singer et al.   NATURE GENETICS

Hepatotoxic effects of therapies for tuberculosis

(2010) Bahaa E. Senousy et al.   Nature Reviews Gastroenterology & Hepatology

Regulatory Action on Rosiglitazone by the U.S. Food and Drug Administration

(2010) Janet Woodcock et al.   NEW ENGLAND JOURNAL OF MEDICINE

Removal of Opioid/Acetaminophen Combination Prescription Pain Medications: Assessing the Evidence for Hepatotoxicity and Consequences of Removal of These Medications

(2010) Edward Michna et al.   PAIN MEDICINE

Trimethoprim-Sulfamethoxazole–Induced Hepatotoxicity in a Pediatric Patient

(2010) Tara L Bell et al.   PHARMACOTHERAPY

Procarbazine-Induced Hepatotoxicity: Case Report and Review of the Literature

(2010) Mark J Fesler et al.   PHARMACOTHERAPY

Nevirapine-Associated Early Hepatotoxicity: Incidence, Risk Factors, and Associated Mortality in a Primary Care ART Programme in South Africa

(2010) Kathryn M. Chu et al.   PLoS One

Acetaminophen-NAPQI Hepatotoxicity: A Cell Line Model System Genome-Wide Association Study

(2010) Ann M. Moyer et al.   TOXICOLOGICAL SCIENCES

Mechanisms of Immune-Mediated Liver Injury

(2010) David H. Adams et al.   TOXICOLOGICAL SCIENCES

Multiple mechanisms underlying troglitazone-induced mitochondrial permeability transition

(2010) Takuya Okuda et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Direct toxicity effects of sulfo-conjugated troglitazone on human hepatocytes

(2010) Sudipta Saha et al.   TOXICOLOGY LETTERS

Isoniazid-induced apoptosis in HepG2 cells: Generation of oxidative stress and Bcl-2 down-regulation

(2010) Smrati Bhadauria et al.   TOXICOLOGY MECHANISMS AND METHODS

FDA proposals to limit the hepatotoxicity of paracetamol (acetaminophen): are they reasonable?

(2010) Garry G. Graham et al.   INFLAMMOPHARMACOLOGY

Acute reactive hepatitis in pregnancy

(2010) Zsófia Ozsvár et al.   ORVOSI HETILAP

An Acute Hepatitis Resembling Autoimmune Hepatitis Occurring During Imatinib Therapy in a Gastrointestinal Stromal Tumor Patient

(2009) Sandra Aliberti et al.   AMERICAN JOURNAL OF CLINICAL ONCOLOGY-CANCER CLINICAL TRIALS

Pharmacogenetics of antiretrovirals

(2009) Valerio Tozzi   ANTIVIRAL RESEARCH

Susceptibility to acetaminophen (APAP) toxicity unexpectedly is decreased during acute viral hepatitis in mice

(2009) Yonas Getachew et al.   BIOCHEMICAL PHARMACOLOGY

How safe is the use of thiazolidinediones in clinical practice?

(2009) CV Rizos et al.   Expert Opinion On Drug Safety

Phenotypic characterization of idiosyncratic drug-induced liver injury: The influence of age and sex

(2009) M. Isabel Lucena et al.   HEPATOLOGY

Hepatitis C, alcohol abuse, and unintentional overdoses are risk factors for acetaminophen-related hepatotoxicity

(2009) Robert P. Myers et al.   HEPATOLOGY

Oral medications with significant hepatic metabolism at higher risk for hepatic adverse events

(2009) Craig Lammert et al.   HEPATOLOGY

Adalimumab-induced Autoimmune Hepatitis

(2009) Tomer Adar et al.   JOURNAL OF CLINICAL GASTROENTEROLOGY

Bacterial- and Viral-Induced Inflammation Increases Sensitivity to Acetaminophen Hepatotoxicity

(2009) Jane F. Maddox et al.   JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES

Genetic variations ofNAT2andCYP2E1and isoniazid hepatotoxicity in a diverse population

(2009) So Yamada et al.   PHARMACOGENOMICS

Nevirapine-induced hepatotoxicity and pharmacogenetics: a retrospective study in a population from Mozambique

(2009) Cinzia Ciccacci et al.   PHARMACOGENOMICS

Enhancing the utility of alanine aminotransferase as a reference standard biomarker for drug-induced liver injury

(2009) Josef S. Ozer et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Troglitazone, but not rosiglitazone, damages mitochondrial DNA and induces mitochondrial dysfunction and cell death in human hepatocytes

(2009) Lyudmila I. Rachek et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

An in vitro drug-induced hepatotoxicity screening system using CYP3A4-expressing and γ-glutamylcysteine synthetase knockdown cells

(2009) Hiroko Hosomi et al.   TOXICOLOGY IN VITRO

Investigation of the role of the thiazolidinedione ring of troglitazone in inducing hepatotoxicity

(2009) Sudipta Saha et al.   TOXICOLOGY LETTERS

Review article: the use of potentially hepatotoxic drugs in patients with liver disease

(2008) N. K. GUPTA et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Causes, Clinical Features, and Outcomes From a Prospective Study of Drug-Induced Liver Injury in the United States

(2008) Naga Chalasani et al.   GASTROENTEROLOGY

Hepatitis C is a predictor of acute liver injury among hospitalizations for acetaminophen overdose in the United States: A nationwide analysis

(2008) Geoffrey C. Nguyen et al.   HEPATOLOGY

HLA-B*5701 Screening for Hypersensitivity to Abacavir

(2008) Simon Mallal et al.   NEW ENGLAND JOURNAL OF MEDICINE