The role of circadian timing system on drug metabolism and detoxification

Human Melanoma Cells under Endoplasmic Reticulum Stress Acquire Resistance to Microtubule-Targeting Drugs through XBP-1-Mediated Activation of Akt

(2015) Chen Chen Jiang et al.   NEOPLASIA

Chronotherapy and the molecular clock: Clinical implications in oncology☆

(2010) Pasquale F. Innominato et al.   ADVANCED DRUG DELIVERY REVIEWS

Role of clock genes in gastrointestinal motility

(2010) Willemijntje A. Hoogerwerf   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

The Role of Clock Genes in Pharmacology

(2010) Georgios K. Paschos et al.   Annual Review of Pharmacology and Toxicology

Circadian Timing in Cancer Treatments

(2010) Francis Lévi et al.   Annual Review of Pharmacology and Toxicology

The Mammalian Circadian Timing System: Organization and Coordination of Central and Peripheral Clocks

(2010) Charna Dibner et al.   Annual Review of Physiology

Circadian Clock-Coordinated 12 Hr Period Rhythmic Activation of the IRE1α Pathway Controls Lipid Metabolism in Mouse Liver

(2010) Gaspard Cretenet et al.   Cell Metabolism

Age-Related Pharmacokinetic and Pharmacodynamic Changes and Related Risk of Adverse Drug Reactions

(2010) A. Corsonello et al.   CURRENT MEDICINAL CHEMISTRY

Activation of xenobiotic receptors: driving into the nucleus

(2010) Haishan Li et al.   Expert Opinion on Drug Metabolism & Toxicology

Circadian Clock Regulates Response to Pesticides in Drosophila via Conserved Pdp1 Pathway

(2010) Laura Michelle Beaver et al.   TOXICOLOGICAL SCIENCES

The clock genes period 1 and period 2 mediate diurnal rhythms in dioxin-induced Cyp1A1 expression in the mouse mammary gland and liver

(2010) Xiaoyu Qu et al.   TOXICOLOGY LETTERS

Rhythmic changes in colonic motility are regulated by period genes

(2009) Willemijntje A. Hoogerwerf et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Activation and clinical significance of the unfolded protein response in breast cancer

(2009) P Scriven et al.   BRITISH JOURNAL OF CANCER

The Role of ATF4 Stabilization and Autophagy in Resistance of Breast Cancer Cells Treated with Bortezomib

(2009) M. Milani et al.   CANCER RESEARCH

Genomic Consequences of Cytochrome P450 2C9 Overexpression in Human Hepatoma Cells

(2009) Céline Narjoz et al.   CHEMICAL RESEARCH IN TOXICOLOGY

The Circadian Clock Components CRY1 and CRY2 Are Necessary to Sustain Sex Dimorphism in Mouse Liver Metabolism

(2009) Isabelle M. Bur et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Rhythmic PER Abundance Defines a Critical Nodal Point for Negative Feedback within the Circadian Clock Mechanism

(2009) Rongmin Chen et al.   MOLECULAR CELL

Sex Differences in the Expression of Hepatic Drug Metabolizing Enzymes

(2009) D. J. Waxman et al.   MOLECULAR PHARMACOLOGY

Salt-sensitive hypertension in circadian clock–deficient Cry-null mice involves dysregulated adrenal Hsd3b6

(2009) Masao Doi et al.   NATURE MEDICINE

Does the Clock Make the Poison? Circadian Variation in Response to Pesticides

(2009) Louisa A. Hooven et al.   PLoS One

Circadian Dysregulation Disrupts Bile Acid Homeostasis

(2009) Ke Ma et al.   PLoS One

Molecular clock is involved in predictive circadian adjustment of renal function

(2009) A. M. Zuber et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

AMPK Regulates the Circadian Clock by Cryptochrome Phosphorylation and Degradation

(2009) K. A. Lamia et al.   SCIENCE

REV-ERBα Participates in Circadian SREBP Signaling and Bile Acid Homeostasis

(2009) Gwendal Le Martelot et al.   PLOS BIOLOGY

Harmonics of Circadian Gene Transcription in Mammals

(2009) Michael E. Hughes et al.   PLoS Genetics

Continuous high expression of XBP1 and GRP78 is important for the survival of bone marrow cells in CCl4-treated cirrhotic liver

(2008) Yoshio Marumoto et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Circadian Expression Profiles of Drug-Processing Genes and Transcription Factors in Mouse Liver

(2008) Y.-K. J. Zhang et al.   DRUG METABOLISM AND DISPOSITION

Circadian Clock-Controlled Intestinal Expression of the Multidrug-Resistance Gene mdr1a in Mice

(2008) Yuichi Murakami et al.   GASTROENTEROLOGY

Regulation of Bile Acid Synthesis by the Nuclear Receptor Rev-erbα

(2008) Hélène Duez et al.   GASTROENTEROLOGY

Setting Clock Speed in Mammals: The CK1ɛ tau Mutation in Mice Accelerates Circadian Pacemakers by Selectively Destabilizing PERIOD Proteins

(2008) Qing-Jun Meng et al.   NEURON

Disruption of period gene expression alters the inductive effects of dioxin on the AhR signaling pathway in the mouse liver

(2008) Xiaoyu Qu et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY