Introduction to computational oral absorption simulation

Toward an Increased Understanding of the Barriers to Colonic Drug Absorption in Humans: Implications for Early Controlled Release Candidate Assessment

(2009) Christer Tannergren et al.   MOLECULAR PHARMACEUTICS

Scaling of in Vitro Membrane Permeability to Predict P-glycoprotein-Mediated Drug Absorption in Vivo

(2008) Y. Shirasaka et al.   DRUG METABOLISM AND DISPOSITION

Improved understanding of the effect of food on drug absorption and bioavailability for lipophilic compounds using an intestinal pig perfusion model

(2008) E.M. Persson et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Theoretical comparison of hydrodynamic diffusion layer models used for dissolution simulation in drug discovery and development

(2008) Kiyohiko Sugano   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Gut instincts: Explorations in intestinal physiology and drug delivery

(2008) Emma L. McConnell et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Mathematical modeling of drug delivery

(2008) J. Siepmann et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Estimation of effective intestinal membrane permeability considering bile micelle solubilisation

(2008) Kiyohiko Sugano   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Solubility Challenge: Can You Predict Solubilities of 32 Molecules Using a Database of 100 Reliable Measurements?

(2008) Antonio Llinàs et al.   Journal of Chemical Information and Modeling

Nucleation and crystal growth in supersaturated solutions of a model drug

(2008) Lennart Lindfors et al.   JOURNAL OF COLLOID AND INTERFACE SCIENCE

Molecular Characteristics for Solid-State Limited Solubility

(2008) Carola M. Wassvik et al.   JOURNAL OF MEDICINAL CHEMISTRY

Applications of Physiologically Based Absorption Models in Drug Discovery and Development

(2008) Neil Parrott et al.   MOLECULAR PHARMACEUTICS

Miniaturized Rotating Disk Intrinsic Dissolution Rate Measurement: Effects of Buffer Capacity in Comparisons to Traditional Wood’s Apparatus

(2008) Alex Avdeef et al.   PHARMACEUTICAL RESEARCH

Rate-Limiting Steps of Oral Absorption for Poorly Water-Soluble Drugs in Dogs; Prediction from a Miniscale Dissolution Test and a Physiologically-Based Computer Simulation

(2008) Ryusuke Takano et al.   PHARMACEUTICAL RESEARCH

Dissolution Improvement and the Mechanism of the Improvement from Cocrystallization of Poorly Water-soluble Compounds

(2008) Koji Shiraki et al.   PHARMACEUTICAL RESEARCH

Dissolution Media Simulating Conditions in the Proximal Human Gastrointestinal Tract: An Update

(2008) Ekarat Jantratid et al.   PHARMACEUTICAL RESEARCH

Evaluation of in vivo dissolution behavior and GI transit of griseofulvin, a BCS class II drug

(2007) Yoshitsugu Fujioka et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Development of a self-emulsifying formulation that reduces the food effect for torcetrapib

(2007) M PERLMAN et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Use of prediction methods to estimate true density of active pharmaceutical ingredients

(2007) Xiaoping Cao et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Theoretical Dissolution Model of Poly-Disperse Drug Particles in Biorelevant Media

(2007) Arimichi Okazaki et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Measurement of Surface pH of Pharmaceutical Solids: A Critical Evaluation of Indicator Dye-Sorption Method and its Comparison With Slurry pH Method

(2007) Madhu Pudipeddi et al.   JOURNAL OF PHARMACEUTICAL SCIENCES