Identification of interspecies difference in hepatobiliary transporters to improve extrapolation of human biliary secretion

LC−MS/MS Mediated Absolute Quantification and Comparison of Bile Salt Export Pump and Breast Cancer Resistance Protein in Livers and Hepatocytes across Species

(2009) Na Li et al.   ANALYTICAL CHEMISTRY

Absolute quantification of multidrug resistance-associated protein 2 (MRP2/ABCC2) using liquid chromatography tandem mass spectrometry

(2008) Na Li et al.   ANALYTICAL BIOCHEMISTRY

Species-specific toxicity of diclofenac and troglitazone in primary human and rat hepatocytes

(2008) Birthe Lauer et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Absolute Difference of Hepatobiliary Transporter Multidrug Resistance-Associated Protein (MRP2/Mrp2) in Liver Tissues and Isolated Hepatocytes from Rat, Dog, Monkey, and Human

(2008) N. Li et al.   DRUG METABOLISM AND DISPOSITION

Effect of Plasma Protein Binding on in Vitro-in Vivo Correlation of Biliary Excretion of Drugs Evaluated by Sandwich-Cultured Rat Hepatocytes

(2008) H. Fukuda et al.   DRUG METABOLISM AND DISPOSITION

Identification of interspecies difference in efflux transporters of hepatocytes from dog, rat, monkey and human

(2008) Meng Li et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Primary hepatocytes as a model to analyze species-specific toxicity and drug metabolism

(2008) Gregor Tuschl et al.   Expert Opinion on Drug Metabolism & Toxicology

Physiologically Based Pharmacokinetic Modeling to Predict Transporter-Mediated Clearance and Distribution of Pravastatin in Humans

(2008) T. Watanabe et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Quantitative Atlas of Membrane Transporter Proteins: Development and Application of a Highly Sensitive Simultaneous LC/MS/MS Method Combined with Novel In-silico Peptide Selection Criteria

(2008) Junichi Kamiie et al.   PHARMACEUTICAL RESEARCH

Involvement of Mrp2 (Abcc2) in biliary excretion of moxifloxacin and its metabolites in the isolated perfused rat liver

(2007) Salwa Ahmed et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

Induction of Mrp3 and Mrp4 transporters during acetaminophen hepatotoxicity is dependent on Nrf2

(2007) Lauren M. Aleksunes et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY