Selecting oral bioavailability enhancing formulations during drug discovery and development

Structure-based prediction of human intestinal membrane permeability for rapidin silicoBCS classification

(2013) Le Sun et al.   BIOPHARMACEUTICS & DRUG DISPOSITION

Recent Progress of Molecular Docking Simulations Applied to Development of Drugs

(2013) Linus Santana Azevedo et al.   Current Bioinformatics

In silico predictions of gastrointestinal drug absorption in pharmaceutical product development: Application of the mechanistic absorption model GI-Sim

(2013) Erik Sjögren et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Automated docking for novel drug discovery

(2013) Martiniano Bello et al.   Expert Opinion on Drug Discovery

How far can virtual screening take us in drug discovery?

(2013) Supratik Kar et al.   Expert Opinion on Drug Discovery

Computational methods for drug design and discovery: focus on China

(2013) Mingyue Zheng et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Systemic and Biophase Bioavailability and Pharmacokinetics of Nanoparticulate Drug Delivery Systems

(2013) Sorin Emilian Leucuta   Current Drug Delivery

Case Studies for Practical Food Effect Assessments across BCS/BDDCS Class Compounds using In Silico, In Vitro, and Preclinical In Vivo Data

(2012) Tycho Heimbach et al.   AAPS Journal

In silicoprediction of drug dissolution and absorption with variation in intestinal pH for BCS class II weak acid drugs: ibuprofen and ketoprofen

(2012) Yasuhiro Tsume et al.   BIOPHARMACEUTICS & DRUG DISPOSITION

The Role of BCS (Biopharmaceutics Classification System) and BDDCS (Biopharmaceutics Drug Disposition Classification System) in Drug Development

(2012) Leslie Z. Benet   JOURNAL OF PHARMACEUTICAL SCIENCES

BDDCS Applied to Over 900 Drugs

(2011) Leslie Z. Benet et al.   AAPS Journal

Molecular Dynamics Simulations of Protein Targets Identified in Mycobacterium tuberculosis

(2011) W. F. de Azevedo   CURRENT MEDICINAL CHEMISTRY

Bio-Inspired Algorithms Applied to Molecular Docking Simulations

(2011) G. Heberle et al.   CURRENT MEDICINAL CHEMISTRY

Selection of oral bioavailability enhancing formulations during drug discovery

(2011) Weijia Zheng et al.   DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY

Formulation design for poorly water-soluble drugs based on biopharmaceutics classification system: Basic approaches and practical applications

(2011) Yohei Kawabata et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Bioavailability Enhancement Strategies: Basics, Formulation Approaches and Regulatory Considerations

(2011) Sarwar Beg et al.   Current Drug Delivery

Pharmaceutical Cocrystals and Their Physicochemical Properties

(2009) Nate Schultheiss et al.   CRYSTAL GROWTH & DESIGN

Computational systems approach for drug target discovery

(2009) Nagasuma Chandra   Expert Opinion on Drug Discovery

Use of the Biopharmaceutical Classification System in Early Drug Development

(2008) M. Sherry Ku   AAPS Journal

Clinical Relevance of Dissolution Testing in Quality by Design

(2008) Paul A. Dickinson et al.   AAPS Journal

Protein Crystallography in Drug Discovery

(2008) Fernanda Canduri et al.   CURRENT DRUG TARGETS

Computational Methods for Calculation of Ligand-Binding Affinity

(2008) Walter de Azevedo Jr. et al.   CURRENT DRUG TARGETS

Applications of hot-melt extrusion for drug delivery

(2008) Michael A Repka et al.   Expert Opinion on Drug Delivery

Bioavailability and Bioequivalence: Focus on Physiological Factors and Variability

(2008) Vangelis Karalis et al.   PHARMACEUTICAL RESEARCH

Particle design of poorly water-soluble drug substances using supercritical fluid technologies

(2007) Takehiko Yasuji et al.   ADVANCED DRUG DELIVERY REVIEWS

Metabolism and Toxicity of Drugs. Two Decades of Progress in Industrial Drug Metabolism

(2007) Thomas A. Baillie   CHEMICAL RESEARCH IN TOXICOLOGY