Drug discovery technologies and strategies for Machupo virus and other New World arenaviruses
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Title
Drug discovery technologies and strategies for Machupo virus and other New World arenaviruses
Authors
Keywords
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Journal
Expert Opinion on Drug Discovery
Volume 7, Issue 7, Pages 613-632
Publisher
Informa Healthcare
Online
2012-05-20
DOI
10.1517/17460441.2012.687719
References
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Note: Only part of the references are listed.- An Antibody Recognizing the Apical Domain of Human Transferrin Receptor 1 Efficiently Inhibits the Entry of All New World Hemorrhagic Fever Arenaviruses
- (2012) G. Helguera et al. JOURNAL OF VIROLOGY
- Depletion of GTP pool is not the predominant mechanism by which ribavirin exerts its antiviral effect on Lassa virus
- (2011) Stephan Ölschläger et al. ANTIVIRAL RESEARCH
- Arenaviruses and hantaviruses: From epidemiology and genomics to antivirals
- (2011) R.N. Charrel et al. ANTIVIRAL RESEARCH
- Inhibition of Junin virus RNA synthesis by an antiviral acridone derivative
- (2011) Claudia S. Sepúlveda et al. ANTIVIRAL RESEARCH
- Structure of the Lassa Virus Nucleoprotein Revealed by X-ray Crystallography, Small-angle X-ray Scattering, and Electron Microscopy
- (2011) Linda Brunotte et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Expanded Potential for Recombinant Trisegmented Lymphocytic Choriomeningitis Viruses: Protein Production, Antibody Production, and In Vivo Assessment of Biological Function of Genes of Interest
- (2011) D. L. Popkin et al. JOURNAL OF VIROLOGY
- Efficient Rescue of Recombinant Lassa Virus Reveals the Influence of S Segment Noncoding Regions on Virus Replication and Virulence
- (2011) C. G. Albarino et al. JOURNAL OF VIROLOGY
- The Major Determinant of Attenuation in Mice of the Candid1 Vaccine for Argentine Hemorrhagic Fever Is Located in the G2 Glycoprotein Transmembrane Domain
- (2011) C. G. Albarino et al. JOURNAL OF VIROLOGY
- Ribavirin Can Be Mutagenic for Arenaviruses
- (2011) H. Moreno et al. JOURNAL OF VIROLOGY
- Machupo Virus Glycoprotein Determinants for Human Transferrin Receptor 1 Binding and Cell Entry
- (2011) Sheli R. Radoshitzky et al. PLoS One
- Structure of the Lassa virus nucleoprotein reveals a dsRNA-specific 3' to 5' exonuclease activity essential for immune suppression
- (2011) K. M. Hastie et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Arenavirus Z protein controls viral RNA synthesis by locking a polymerase-promoter complex
- (2011) P. J. Kranzusch et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Crystal structure of the Lassa virus nucleoprotein-RNA complex reveals a gating mechanism for RNA binding
- (2011) K. M. Hastie et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Arenavirus reverse genetics: New approaches for the investigation of arenavirus biology and development of antiviral strategies
- (2011) Sebastien E. Emonet et al. VIROLOGY
- A STAT-1 knockout mouse model for Machupo virus pathogenesis
- (2011) Steven B Bradfute et al. Virology Journal
- T-705 (Favipiravir) Inhibition of Arenavirus Replication in Cell Culture
- (2010) Michelle Mendenhall et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Inhibition of arenavirus infection by thiuram and aromatic disulfides
- (2010) Claudia S. Sepúlveda et al. ANTIVIRAL RESEARCH
- An antiviral disulfide compound blocks interaction between arenavirus Z protein and cellular promyelocytic leukemia protein
- (2010) C.C. García et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Imidazo[2,1-b]thiazole carbohydrate derivatives: Synthesis and antiviral activity against Junin virus, agent of Argentine hemorrhagic fever
- (2010) José Sebastián Barradas et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Novel therapeutic targets for arenavirus hemorrhagic fevers
- (2010) Cybele C García et al. Future Virology
- Reverse Genetics Generation of Chimeric Infectious Junin/Lassa Virus Is Dependent on Interaction of Homologous Glycoprotein Stable Signal Peptide and G2 Cytoplasmic Domains
- (2010) C. G. Albarino et al. JOURNAL OF VIROLOGY
- Rescue from Cloned cDNAs and In Vivo Characterization of Recombinant Pathogenic Romero and Live-Attenuated Candid #1 Strains of Junin Virus, the Causative Agent of Argentine Hemorrhagic Fever Disease
- (2010) S. F. Emonet et al. JOURNAL OF VIROLOGY
- Mice Lacking Alpha/Beta and Gamma Interferon Receptors Are Susceptible to Junin Virus Infection
- (2010) O. A. Kolokoltsova et al. JOURNAL OF VIROLOGY
- Cap binding and immune evasion revealed by Lassa nucleoprotein structure
- (2010) Xiaoxuan Qi et al. NATURE
- Genome-wide RNAi screen identifies human host factors crucial for influenza virus replication
- (2010) Alexander Karlas et al. NATURE
- Structural basis for receptor recognition by New World hemorrhagic fever arenaviruses
- (2010) Jonathan Abraham et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Assembly of a functional Machupo virus polymerase complex
- (2010) P. J. Kranzusch et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Novel approaches in anti-arenaviral drug development
- (2010) Andrew M. Lee et al. VIROLOGY
- Bunyaviridae RNA Polymerases (L-Protein) Have an N-Terminal, Influenza-Like Endonuclease Domain, Essential for Viral Cap-Dependent Transcription
- (2010) Juan Reguera et al. PLoS Pathogens
- The N-Terminal Domain of the Arenavirus L Protein Is an RNA Endonuclease Essential in mRNA Transcription
- (2010) Benjamin Morin et al. PLoS Pathogens
- Efficacy of favipiravir (T-705) and T-1106 pyrazine derivatives in phlebovirus disease models
- (2009) Brian B. Gowen et al. ANTIVIRAL RESEARCH
- Involvement of cellular proteins in Junin arenavirus entry
- (2009) M. Guadalupe Martinez et al. Biotechnology Journal
- Development of Infectious Clones for Virulent and Avirulent Pichinde Viruses: a Model Virus To Study Arenavirus-Induced Hemorrhagic Fevers
- (2009) S. Lan et al. JOURNAL OF VIROLOGY
- Z Proteins of New World Arenaviruses Bind RIG-I and Interfere with Type I Interferon Induction
- (2009) L. Fan et al. JOURNAL OF VIROLOGY
- Intersubunit Interactions Modulate pH-Induced Activation of Membrane Fusion by the Junin Virus Envelope Glycoprotein GPC
- (2009) J. York et al. JOURNAL OF VIROLOGY
- Efficient Reverse Genetics Generation of Infectious Junin Viruses Differing in Glycoprotein Processing
- (2009) C. G. Albarino et al. JOURNAL OF VIROLOGY
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- (2009) L. Martinez-Sobrido et al. JOURNAL OF VIROLOGY
- T-705 (favipiravir) activity against lethal H5N1 influenza A viruses
- (2009) M. Kiso et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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- Characterization of Junín virus particles inactivated by a zinc finger-reactive compound
- (2009) Cybele C. García et al. VIRUS RESEARCH
- Participation of the phosphatidylinositol 3-kinase/Akt pathway in Junín virus replication in vitro
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- Host-Species Transferrin Receptor 1 Orthologs Are Cellular Receptors for Nonpathogenic New World Clade B Arenaviruses
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- Chapare Virus, a Newly Discovered Arenavirus Isolated from a Fatal Hemorrhagic Fever Case in Bolivia
- (2008) Simon Delgado et al. PLoS Pathogens
- Treatment of Argentine hemorrhagic fever
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- New opportunities for field research on the pathogenesis and treatment of Lassa fever
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