Methodological advances in drug discovery for Chagas disease

Successful Treatment with Posaconazole of a Patient with Chronic Chagas Disease and Systemic Lupus Erythematosus

(2010) María-Jesús Pinazo et al.   AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE

Trypanocidal Activity of Aziridinyl Nitrobenzamide Prodrugs

(2010) C. Bot et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Image-Based High-Throughput Drug Screening Targeting the Intracellular Stage of Trypanosoma cruzi, the Agent of Chagas' Disease

(2010) J. C. Engel et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Cellular analysis of host cell infection by different developmental stages of Trypanosoma cruzi

(2010) Luis Florencio-Martínez et al.   EXPERIMENTAL PARASITOLOGY

New method for quantification of Trypanosoma cruzi in animal’s tissue in the chronic phase of experimental Chagas' disease

(2010) Viviane Rodrigues Esperandim et al.   PARASITOLOGY RESEARCH

In Vitro and In Vivo High-Throughput Assays for the Testing of Anti-Trypanosoma cruzi Compounds

(2010) Adriana M. C. Canavaci et al.   PLoS Neglected Tropical Diseases

Specific chemotherapy of Chagas disease: Relevance, current limitations and new approaches

(2009) Julio A. Urbina   ACTA TROPICA

Changes inTrypanosoma cruzi–Specific Immune Responses after Treatment: Surrogate Markers of Treatment Efficacy

(2009) Susana A. Laucella et al.   CLINICAL INFECTIOUS DISEASES

Side effects of benznidazole as treatment in chronic Chagas disease: fears and realities

(2009) Rodolfo Viotti et al.   Expert Review of Anti-Infective Therapy

Reporter genes facilitating discovery of drugs targeting protozoan parasites

(2009) Anuradha Dube et al.   TRENDS IN PARASITOLOGY

Neglected Disease Research and Development: How Much Are We Really Spending?

(2009) Mary Moran et al.   PLOS MEDICINE

Identification of Three Classes of Heteroaromatic Compounds with Activity against Intracellular Trypanosoma cruzi by Chemical Library Screening

(2009) Esther Bettiol et al.   PLoS Neglected Tropical Diseases

Discovery of novel inhibitors of Trypanosoma cruzi trans-sialidase from in silico screening

(2008) João Neres et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Bioluminescent imaging of Trypanosoma cruzi infection

(2008) Kenneth V. Hyland et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

Drug-induced cure drives conversion to a stable and protective CD8+ T central memory response in chronic Chagas disease

(2008) Juan M Bustamante et al.   NATURE MEDICINE

HLA Class I-T Cell Epitopes from trans-Sialidase Proteins Reveal Functionally Distinct Subsets of CD8+ T Cells in Chronic Chagas Disease

(2008) María G. Alvarez et al.   PLoS Neglected Tropical Diseases

High Throughput Selection of Effective Serodiagnostics for Trypanosoma cruzi infection

(2008) Gretchen Cooley et al.   PLoS Neglected Tropical Diseases

Cell culture and animal infection with distinct Trypanosoma cruzi strains expressing red and green fluorescent proteins

(2007) S.F. Pires et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY