Advances in microfluidics for drug discovery

Hydrodynamic gating valve for microfluidic fluorescence-activated cell sorting

(2010) Pu Chen et al.   ANALYTICA CHIMICA ACTA

Label-free cell separation and sorting in microfluidic systems

(2010) Daniel R. Gossett et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

SlipChip for Immunoassays in Nanoliter Volumes

(2010) Weishan Liu et al.   ANALYTICAL CHEMISTRY

Multiplexed Real-Time Polymerase Chain Reaction on a Digital Microfluidic Platform

(2010) Zhishan Hua et al.   ANALYTICAL CHEMISTRY

Microfluidic Cell Culture and Metabolism Detection with Electrospray Ionization Quadrupole Time-of-Flight Mass Spectrometer

(2010) Dan Gao et al.   ANALYTICAL CHEMISTRY

Nanoliter Multiplex PCR Arrays on a SlipChip

(2010) Feng Shen et al.   ANALYTICAL CHEMISTRY

Latest Developments in Microfluidic Cell Biology and Analysis Systems

(2010) Georgette B. Salieb-Beugelaar et al.   ANALYTICAL CHEMISTRY

Acoustophoretic Synchronization of Mammalian Cells in Microchannels

(2010) Patrick Thévoz et al.   ANALYTICAL CHEMISTRY

Microfluidic Technologies for Temporal Perturbations of Chemotaxis

(2010) Daniel Irimia   Annual Review of Biomedical Engineering

Protein Crystallization Using Microfluidic Technologies Based on Valves, Droplets, and SlipChip

(2010) Liang Li et al.   Annual Review of Biophysics

A microfluidic imaging chamber for the direct observation of chemotactic transmigration

(2010) Mark T. Breckenridge et al.   BIOMEDICAL MICRODEVICES

Quantitative Cell-Based Reporter Gene Assays Using Droplet-Based Microfluidics

(2010) Jean-Christophe Baret et al.   CHEMISTRY & BIOLOGY

High-Throughput Screening of Enzymes by Retroviral Display Using Droplet-Based Microfluidics

(2010) Lucia Granieri et al.   CHEMISTRY & BIOLOGY

Analytical biotechnology: from single molecule and single cell analyses to population dynamics of metabolites and cells

(2010) Andreas Schmid et al.   CURRENT OPINION IN BIOTECHNOLOGY

Chemical and biological single cell analysis

(2010) Andreas Schmid et al.   CURRENT OPINION IN BIOTECHNOLOGY

Microfluidic impedance-based flow cytometry

(2010) Karen C. Cheung et al.   CYTOMETRY PART A

Microfluidic cell arrays in tumor analysis: new prospects for integrated cytomics

(2010) Donald Wlodkowic et al.   EXPERT REVIEW OF MOLECULAR DIAGNOSTICS

High-throughput automated droplet microfluidic system for screening of reaction conditions

(2010) Krzysztof Churski et al.   LAB ON A CHIP

Designed pneumatic valve actuators for controlled droplet breakup and generation

(2010) Jae-Hoon Choi et al.   LAB ON A CHIP

Large-scale investigation of the olfactory receptor space using a microfluidic microwell array

(2010) Xavier A. Figueroa et al.   LAB ON A CHIP

High throughput assembly of spatially controlled 3D cell clusters on a micro/nanoplatform

(2010) Daniel Gallego-Perez et al.   LAB ON A CHIP

An automated two-phase microfluidic system for kinetic analyses and the screening of compound libraries

(2010) Jenifer Clausell-Tormos et al.   LAB ON A CHIP

Guiding neuron development with planar surface gradients of substrate cues deposited using microfluidic devices

(2010) Larry J. Millet et al.   LAB ON A CHIP

Microfluidic cell culture systems for drug research

(2010) Min-Hsien Wu et al.   LAB ON A CHIP

Microfluidic tools for cell biological research

(2010) Guilhem Velve-Casquillas et al.   Nano Today

Where microbiology meets microengineering: design and applications of reporter bacteria

(2010) Jan Roelof van der Meer et al.   NATURE REVIEWS MICROBIOLOGY

Ultrahigh-throughput screening in drop-based microfluidics for directed evolution

(2010) J. J. Agresti et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Reconstituting Organ-Level Lung Functions on a Chip

(2010) D. Huh et al.   SCIENCE

Acoustic Whole Blood Plasmapheresis Chip for Prostate Specific Antigen Microarray Diagnostics

(2009) Andreas Lenshof et al.   ANALYTICAL CHEMISTRY

User Configurable Microfluidic Device for Multiplexed Immunoassays Based on DNA-Directed Assembly

(2009) Hendrik Schroeder et al.   ANALYTICAL CHEMISTRY

Microfluidic Self-Sorting of Mammalian Cells to Achieve Cell Cycle Synchrony by Hydrophoresis

(2009) Sungyoung Choi et al.   ANALYTICAL CHEMISTRY

Coupling Microdroplet Microreactors with Mass Spectrometry: Reading the Contents of Single Droplets Online

(2009) Luis M. Fidalgo et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Multistep Synthesis Using Modular Flow Reactors: Bestmann-Ohira Reagent for the Formation of Alkynes and Triazoles

(2009) Ian R. Baxendale et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Multistep Microchemical Synthesis Enabled by Microfluidic Distillation

(2009) Ryan L. Hartman et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The Continuous-Flow Synthesis of Ibuprofen

(2009) Andrew R. Bogdan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A microfluidic DNA computing processor for gene expression analysis and gene drug synthesis

(2009) Yu Zhang et al.   Biomicrofluidics

Characterization of a gastrointestinal tract microscale cell culture analog used to predict drug toxicity

(2009) Gretchen J. Mahler et al.   BIOTECHNOLOGY AND BIOENGINEERING

Droplet-based compartmentalization of chemically separated components in two-dimensional separations

(2009) X. Z. Niu et al.   CHEMICAL COMMUNICATIONS

Suzuki–Miyaura coupling reactions in aqueous microdroplets with catalytically active fluorous interfaces

(2009) Ashleigh B. Theberge et al.   CHEMICAL COMMUNICATIONS

A Microfluidic Approach for a Continuous Crystallization of Drug Carrier Nanoparticles

(2009) K. Jasch et al.   CHEMICAL ENGINEERING & TECHNOLOGY

A microwell array device with integrated microfluidic components for enhanced single-cell analysis

(2009) Sara Lindström et al.   ELECTROPHORESIS

Multiparameter Screening on SlipChip Used for Nanoliter Protein Crystallization Combining Free Interface Diffusion and Microbatch Methods

(2009) Liang Li et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Agarose microwell based neuronal micro-circuit arrays on microelectrode arrays for high throughput drug testing

(2009) Gyumin Kang et al.   LAB ON A CHIP

An integrated microfluidic device for large-scale in situ click chemistry screening

(2009) Yanju Wang et al.   LAB ON A CHIP

Nanowire and nanotube transistors for lab-on-a-chip applications

(2009) Minbaek Lee et al.   LAB ON A CHIP

Soft inertial microfluidics for high throughput separation of bacteria from human blood cells

(2009) Zhigang Wu et al.   LAB ON A CHIP

A micro cell culture analog (µCCA) with 3-D hydrogel culture of multiple cell lines to assess metabolism-dependent cytotoxicity of anti-cancer drugs

(2009) Jong Hwan Sung et al.   LAB ON A CHIP

SlipChip

(2009) Wenbin Du et al.   LAB ON A CHIP

A continuous high-throughput bioparticle sorter based on 3D traveling-wave dielectrophoresis

(2009) I-Fang Cheng et al.   LAB ON A CHIP

Inertial microfluidics for continuous particle separation in spiral microchannels

(2009) Sathyakumar S. Kuntaegowdanahalli et al.   LAB ON A CHIP

Fluorescence-activated droplet sorting (FADS): efficient microfluidic cell sorting based on enzymatic activity

(2009) Jean-Christophe Baret et al.   LAB ON A CHIP

Macro- and microscale fluid flow systems for endothelial cell biology

(2009) Edmond W. K. Young et al.   LAB ON A CHIP

A multi-layer microfluidic device for efficient culture and analysis of renal tubular cells

(2009) Kyung-Jin Jang et al.   LAB ON A CHIP

Integrated microfluidic reactors

(2009) Wei-Yu Lin et al.   Nano Today

Droplet microfluidic technology for single-cell high-throughput screening

(2009) E. Brouzes et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Differentiation of Neural Progenitor Cells in a Microfluidic Chip-Generated Cytokine Gradient

(2009) Joong Yull Park et al.   STEM CELLS

High-throughput cellular microarray platforms: applications in drug discovery, toxicology and stem cell research

(2009) Tiago G. Fernandes et al.   TRENDS IN BIOTECHNOLOGY

Synthetic Biology for Synthetic Chemistry

(2008) Jay D. Keasling   ACS Chemical Biology

The plug-based nanovolume Microcapillary Protein Crystallization System (MPCS)

(2008) Cory J. Gerdts et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Current development in microfluidic immunosensing chip

(2008) Terence G. Henares et al.   ANALYTICA CHIMICA ACTA

Equilibrium Separation and Filtration of Particles Using Differential Inertial Focusing

(2008) Dino Di Carlo et al.   ANALYTICAL CHEMISTRY

High-Throughput Quantitative Polymerase Chain Reaction in Picoliter Droplets

(2008) Margaret Macris Kiss et al.   ANALYTICAL CHEMISTRY

An Equilibrium Method for Continuous-Flow Cell Sorting Using Dielectrophoresis

(2008) M. D. Vahey et al.   ANALYTICAL CHEMISTRY

A World-to-Chip Interface for Digital Microfluidics

(2008) Hao Yang et al.   ANALYTICAL CHEMISTRY

Continuous-Flow Polymerase Chain Reaction of Single-Copy DNA in Microfluidic Microdroplets

(2008) Yolanda Schaerli et al.   ANALYTICAL CHEMISTRY

From Microdroplets to Microfluidics: Selective Emulsion Separation in Microfluidic Devices

(2008) Luis M. Fidalgo et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Chemical Analysis of Single Cells

(2008) Laura M. Borland et al.   Annual Review of Analytical Chemistry

Cell Culture Models in Microfluidic Systems

(2008) Ivar Meyvantsson et al.   Annual Review of Analytical Chemistry

Microfeature guided skeletal muscle tissue engineering for highly organized 3-dimensional free-standing constructs

(2008) Mai T. Lam et al.   BIOMATERIALS

In vitro analysis of a hepatic device with intrinsic microvascular-based channels

(2008) Amedeo Carraro et al.   BIOMEDICAL MICRODEVICES

Microfluidic aqueous two phase system for leukocyte concentration from whole blood

(2008) Jeffrey R. SooHoo et al.   BIOMEDICAL MICRODEVICES

Generating steep, shear-free gradients of small molecules for cell culture

(2008) Taesung Kim et al.   BIOMEDICAL MICRODEVICES

Advances in laboratory evolution of enzymes

(2008) Shimon Bershtein et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Evaluation of the Heterogeneously Catalyzed Strecker Reaction Conducted Under Continuous Flow

(2008) Charlotte Wiles et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Microvortex for focusing, guiding and sorting of particles

(2008) Chia-Hsien Hsu et al.   LAB ON A CHIP

Pillar-induced droplet merging in microfluidic circuits

(2008) Xize Niu et al.   LAB ON A CHIP

Microdroplets: A sea of applications?

(2008) Ansgar Huebner et al.   LAB ON A CHIP

Characterization of drug metabolites and cytotoxicity assay simultaneously using an integrated microfluidic device

(2008) Bo Ma et al.   LAB ON A CHIP

Microfluidic crystallization

(2008) Jacques Leng et al.   LAB ON A CHIP

Simple, robust storage of drops and fluids in a microfluidic device

(2008) Hakim Boukellal et al.   LAB ON A CHIP

A microfluidics approach for the isolation of nucleated red blood cells (NRBCs) from the peripheral blood of pregnant women

(2008) R. Huang et al.   PRENATAL DIAGNOSIS

Microfluidic high-throughput encapsulation and hydrodynamic self-sorting of single cells

(2008) M. Chabert et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Microfluidic Synthesis of Nanomaterials

(2008) Yujun Song et al.   Small

Generation and manipulation of “smart” droplets

(2008) Xize Niu et al.   Soft Matter

Microfluidic chips for cell sorting

(2007) Pu Chen   Frontiers in Bioscience-Landmark