Ligand-directed profiling: applications to target drug discovery in cancer

Cetuximab, its clinical use and future perspectives

(2009) Fernando Rivera et al.   ANTI-CANCER DRUGS

The neovasculature homing motif NGR: more than meets the eye

(2008) A. Corti et al.   BLOOD

Integrating Global Gene Expression and Radiation Survival Parameters across the 60 Cell Lines of the National Cancer Institute Anticancer Drug Screen

(2008) S. A. Amundson et al.   CANCER RESEARCH

A Subset of Host B Lymphocytes Controls Melanoma Metastasis through a Melanoma Cell Adhesion Molecule/MUC18-Dependent Interaction: Evidence from Mice and Humans

(2008) F. I. Staquicini et al.   CANCER RESEARCH

What Does Systems Biology Mean for Drug Development?

(2008) Andre Schrattenholz et al.   CURRENT MEDICINAL CHEMISTRY

Targeted Induction of Lung Endothelial Cell Apoptosis Causes Emphysema-like Changes in the Mouse

(2008) Ricardo J. Giordano et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Phase II Trial of Gefitinib Monotherapy in Chemotherapy-Naïve Patients of 75 Years or Older with Advanced Non-small Cell Lung Cancer

(2008) Noriyuki Ebi et al.   Journal of Thoracic Oncology

Profiling SLCO and SLC22 genes in the NCI-60 cancer cell lines to identify drug uptake transporters

(2008) M. Okabe et al.   MOLECULAR CANCER THERAPEUTICS

A Ligand Peptide Motif Selected from a Cancer Patient Is a Receptor-Interacting Site within Human Interleukin-11

(2008) Marina Cardó-Vila et al.   PLoS One

A preclinical model for predicting drug response in soft-tissue sarcoma with targeted AAVP molecular imaging

(2008) A. Hajitou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Beyond Receptor Expression Levels: The Relevance of Target Accessibility in Ligand-Directed Pharmacodelivery Systems

(2008) Michael G. Ozawa et al.   TRENDS IN CARDIOVASCULAR MEDICINE

Applications of Metabolomics in Drug Discovery and Development

(2008) David S Wishart   Drugs in research & development