Short interfering RNA and the central nervous system: development of nonviral delivery systems

Single-Stranded RNAs Use RNAi to Potently and Allele-Selectively Inhibit Mutant Huntingtin Expression

(2012) Dongbo Yu et al.   CELL

Focused ultrasound for targeted delivery of siRNA and efficient knockdown of Htt expression

(2012) Alison Burgess et al.   JOURNAL OF CONTROLLED RELEASE

Intranasal Delivery of HMGB1 siRNA Confers Target Gene Knockdown and Robust Neuroprotection in the Postischemic Brain

(2012) Il-Doo Kim et al.   MOLECULAR THERAPY

Intranasal delivery of siRNA to the olfactory bulbs of mice via the olfactory nerve pathway

(2012) Dan B. Renner et al.   NEUROSCIENCE LETTERS

Intranasal delivery of biologics to the central nervous system

(2011) Jeffrey J. Lochhead et al.   ADVANCED DRUG DELIVERY REVIEWS

A rapid, targeted, neuron-selective, in vivo knockdown following a single intracerebroventricular injection of a novel chemically modified siRNA in the adult rat brain

(2011) Hidemitsu Nakajima et al.   JOURNAL OF BIOTECHNOLOGY

Efficient In Vivo Delivery of siRNA Into Brain Capillary Endothelial Cells Along With Endogenous Lipoprotein

(2011) Hiroya Kuwahara et al.   MOLECULAR THERAPY

Delivery of siRNA to the mouse brain by systemic injection of targeted exosomes

(2011) Lydia Alvarez-Erviti et al.   NATURE BIOTECHNOLOGY

High-Density Lipoprotein Facilitates In Vivo Delivery of α-Tocopherol–Conjugated Short-Interfering RNA to the Brain

(2010) Yoshitaka Uno et al.   HUMAN GENE THERAPY

Targeted Delivery of siRNA to Macrophages for Anti-inflammatory Treatment

(2010) Sang-Soo Kim et al.   MOLECULAR THERAPY

Challenges and opportunities in CNS delivery of therapeutics for neurodegenerative diseases

(2009) Thomas M Barchet et al.   Expert Opinion on Drug Delivery

Intracerebroventricular Administration of Drugs

(2009) Aaron M Cook et al.   PHARMACOTHERAPY