The future of prodrugs – design by quantum mechanics methods

Comparative study of the AT1 receptor prodrug antagonist candesartan cilexetil with other sartans on the interactions with membrane bilayers

(2012) Charalambos Fotakis et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Prodrugs of Acyclovir - A Computational Approach

(2012) Rafik Karaman et al.   Chemical Biology & Drug Design

Targeted prodrugs in oral drug delivery: the modern molecular biopharmaceutical approach

(2012) Arik Dahan et al.   Expert Opinion on Drug Delivery

Prodrugs of fumarate esters for the treatment of psoriasis and multiple sclerosis—a computational approach

(2012) Rafik Karaman et al.   JOURNAL OF MOLECULAR MODELING

Transdermal Delivery of Atenolol: Effect of Prodrugs and Iontophoresis

(2012) B. Anroop et al.   Current Drug Delivery

Computational-Aided Design for Dopamine Prodrugs Based on Novel Chemical Approach

(2011) Rafik Karaman   Chemical Biology & Drug Design

Computer-assisted design for paracetamol masking bitter taste prodrugs

(2011) Hatem Hejaz et al.   JOURNAL OF MOLECULAR MODELING

Computer-assisted design for atenolol prodrugs for the use in aqueous formulations

(2011) Rafik Karaman et al.   JOURNAL OF MOLECULAR MODELING

Analyzing the efficiency in intramolecular amide hydrolysis of Kirby’s N-alkylmaleamic acids – A computational approach

(2011) Rafik Karaman   Computational and Theoretical Chemistry

The role of proximity orientation in intramolecular proton transfer reactions

(2011) Rafik Karaman   Computational and Theoretical Chemistry

The effective molarity (EM) – A computational approach

(2010) Rafik Karaman   BIOORGANIC CHEMISTRY

Research Article: Computer-Assisted Design of Pro-drugs for Antimalarial Atovaquone

(2010) Rafik Karaman et al.   Chemical Biology & Drug Design

Prodrugs of aza nucleosides based on proton transfer reaction

(2010) Rafik Karaman   JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN

Prodrugs: Some Thoughts and Current Issues

(2010) Valentino J. Stella   JOURNAL OF PHARMACEUTICAL SCIENCES

Tranexamic Acid Treatment for Heavy Menstrual Bleeding

(2010) Andrea S. Lukes et al.   OBSTETRICS AND GYNECOLOGY

A computational analysis of intramolecularity in proton transfer reactions

(2010) Rafik Karaman et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

The efficiency of proton transfer in Kirby’s enzyme model, a computational approach

(2010) Rafik Karaman   TETRAHEDRON LETTERS

Prodrug Approaches for Enhancing the Bioavailability of Drugs with Low Solubility

(2009) Christa E. Müller   CHEMISTRY & BIODIVERSITY

Cleavage of Menger’s aliphatic amide: A model for peptidase enzyme solely explained by proximity orientation in intramolecular proton transfer

(2009) Rafik Karaman   JOURNAL OF MOLECULAR STRUCTURE-THEOCHEM

Taste Masking by Spray-Drying Technique

(2008) Divyakumar Bora et al.   AAPS PHARMSCITECH

Preparation and Evaluation of Taste Masked Famotidine Formulation Using Drug/β-cyclodextrin/Polymer Ternary Complexation Approach

(2008) Ashok R. Patel et al.   AAPS PHARMSCITECH

A new mathematical equation relating activation energy to bond angle and distance: A key for understanding the role of acceleration in lactonization of the trimethyl lock system

(2008) Rafik Karaman   BIOORGANIC CHEMISTRY

Antiparkinson Prodrugs

(2008) Antonio Di Stefano et al.   MOLECULES

Analysis of Menger’s ‘spatiotemporal hypothesis’

(2008) Rafik Karaman   TETRAHEDRON LETTERS