Delivering bioactive molecules as instructive cues to engineered tissues

RNA interference therapy via functionalized scaffolds

(2011) Michael Monaghan et al.   ADVANCED DRUG DELIVERY REVIEWS

The effects of covalently immobilized hyaluronic acid substrates on the adhesion, expansion, and differentiation of embryonic stem cells for in vitro tissue engineering

(2011) Binata Joddar et al.   BIOMATERIALS

Elastin-like protein matrix reinforced with collagen microfibers for soft tissue repair

(2011) Jeffrey M. Caves et al.   BIOMATERIALS

A 3D cartilage – Inflammatory cell culture system for the modeling of human osteoarthritis

(2011) Lin Sun et al.   BIOMATERIALS

Effects of protein dose and delivery system on BMP-mediated bone regeneration

(2011) Joel D. Boerckel et al.   BIOMATERIALS

A 3D aligned microfibrous myocardial tissue construct cultured under transient perfusion

(2011) Halime Kenar et al.   BIOMATERIALS

Human corneal endothelial cell growth on a silk fibroin membrane

(2011) Peter W. Madden et al.   BIOMATERIALS

Signaling circuitries controlling stem cell fate: to be or not to be

(2011) Ramiro Iglesias-Bartolome et al.   CURRENT OPINION IN CELL BIOLOGY

Impact of WNT signaling on tissue lineage differentiation in the early mouse embryo

(2011) Satomi S. Tanaka et al.   DEVELOPMENT GROWTH & DIFFERENTIATION

Extracellular Movement of Signaling Molecules

(2011) Patrick Müller et al.   DEVELOPMENTAL CELL

Co-encapsulation of bioengineered IGF-II-producing cells and pancreatic islets: effect on beta-cell survival

(2011) G Jourdan et al.   GENE THERAPY

Growth factor/heparin-immobilized collagen gel system enhances viability of transplanted hepatocytes and induces angiogenesis

(2011) Yung-Te Hou et al.   JOURNAL OF BIOSCIENCE AND BIOENGINEERING

Extracellular matrix and cell signalling: the dynamic cooperation of integrin, proteoglycan and growth factor receptor

(2011) Soo-Hyun Kim et al.   JOURNAL OF ENDOCRINOLOGY

Covalent Growth Factor Immobilization Strategies for Tissue Repair and Regeneration

(2011) Kristyn S. Masters   MACROMOLECULAR BIOSCIENCE

Nanoengineering the Heart: Conductive Scaffolds Enhance Connexin 43 Expression

(2011) Jin-Oh You et al.   NANO LETTERS

Spatially controlled simultaneous patterning of multiple growth factors in three-dimensional hydrogels

(2011) Ryan G. Wylie et al.   NATURE MATERIALS

Nanowired three-dimensional cardiac patches

(2011) Tal Dvir et al.   Nature Nanotechnology

TGF-β signaling is required for maintenance of retinal ganglion cell differentiation and survival

(2011) T.E. Walshe et al.   NEUROSCIENCE

Humanized mice with ectopic artificial liver tissues

(2011) A. A. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Wnt signaling and a Smad pathway blockade direct the differentiation of human pluripotent stem cells to multipotent neural crest cells

(2011) L. Menendez et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Morphological and Biochemical Analysis Comparative Study of the Collagen Products Biopad, Promogram, Puracol, and Colactive

(2011) Jeffrey C. Karr et al.   Advances in Skin & Wound Care

Bioinspired Materials for Controlling Stem Cell Fate

(2010) Omar Z. Fisher et al.   ACCOUNTS OF CHEMICAL RESEARCH

Ingrowth of human mesenchymal stem cells into porous silk particle reinforced silk composite scaffolds: An in vitro study

(2010) Danielle N. Rockwood et al.   Acta Biomaterialia

Amino-modified silica surfaces efficiently immobilize bone morphogenetic protein 2 (BMP2) for medical purposes

(2010) Nina Ehlert et al.   Acta Biomaterialia

Silk-based delivery systems of bioactive molecules

(2010) Keiji Numata et al.   ADVANCED DRUG DELIVERY REVIEWS

Stimuli-Responsive Porous Hydrogels at Interfaces for Molecular Filtration, Separation, Controlled Release, and Gating in Capsules and Membranes

(2010) Ihor Tokarev et al.   ADVANCED MATERIALS

Remotely Triggerable Drug Delivery Systems

(2010) Brian P. Timko et al.   ADVANCED MATERIALS

SDF-1 axis and myocardial repair

(2010) Marcello Rota   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

The acceleration of implant osseointegration by liposomal Wnt3a

(2010) Antoine Popelut et al.   BIOMATERIALS

Dual delivery of VEGF and MCP-1 to support endothelial cell transplantation for therapeutic vascularization

(2010) Steven M. Jay et al.   BIOMATERIALS

Enhanced proteolytic degradation of molecularly engineered PEG hydrogels in response to MMP-1 and MMP-2

(2010) J. Patterson et al.   BIOMATERIALS

An anisotropic nanofiber/microsphere composite with controlled release of biomolecules for fibrous tissue engineering

(2010) Lara C. Ionescu et al.   BIOMATERIALS

A bFGF-releasing silk/PLGA-based biohybrid scaffold for ligament/tendon tissue engineering using mesenchymal progenitor cells

(2010) Sambit Sahoo et al.   BIOMATERIALS

The use of micropatterning to control smooth muscle myosin heavy chain expression and limit the response to transforming growth factor β1 in vascular smooth muscle cells

(2010) Corin Williams et al.   BIOMATERIALS

A bioactive self-assembled membrane to promote angiogenesis

(2010) Lesley W. Chow et al.   BIOMATERIALS

The effect of immobilization of heparin and bone morphogenic protein-2 (BMP-2) to titanium surfaces on inflammation and osteoblast function

(2010) Sung Eun Kim et al.   BIOMATERIALS

An alginate-based hybrid system for growth factor delivery in the functional repair of large bone defects

(2010) Yash M. Kolambkar et al.   BIOMATERIALS

The promotion of myocardial repair by the sequential delivery of IGF-1 and HGF from an injectable alginate biomaterial in a model of acute myocardial infarction

(2010) Emil Ruvinov et al.   BIOMATERIALS

The spreading, migration and proliferation of mouse mesenchymal stem cells cultured inside hyaluronic acid hydrogels

(2010) Yuguo Lei et al.   BIOMATERIALS

Polysaccharide-modified synthetic polymeric biomaterials

(2010) Aaron D. Baldwin et al.   BIOPOLYMERS

Liposomal Formulations of Thrombomodulin Increase Engraftment after Intraportal Islet Transplantation

(2010) Wanxing Cui et al.   CELL TRANSPLANTATION

Programmable microfluidic patterning of protein gradients on hydrogels

(2010) Simone Allazetta et al.   CHEMICAL COMMUNICATIONS

Triggered drug delivery from biomaterials

(2010) Colin P McCoy et al.   Expert Opinion on Drug Delivery

In vivo evaluation of MMP sensitive high-molecular weight HA-based hydrogels for bone tissue engineering

(2010) Jungju Kim et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

RNA interference by nanofiber-based siRNA delivery system

(2010) Haoqing Cao et al.   JOURNAL OF CONTROLLED RELEASE

Bioactive Electrospun Silver Nanoparticles-Containing Polyurethane Nanofibers as Wound Dressings

(2010) Jyh-Ping Chen et al.   JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY

Characterization of electrospun poly(L-lactide) and gold nanoparticle composite scaffolds for skeletal muscle tissue engineering

(2010) K. D. McKeon-Fischer et al.   Journal of Tissue Engineering and Regenerative Medicine

Preparation of Monodisperse Chitosan Microcapsules with Hollow Structures Using the SPG Membrane Emulsification Technique

(2010) Kazuki Akamatsu et al.   LANGMUIR

Stem Cell Microenvironments - Unveiling the Secret of How Stem Cell Fate is Defined

(2010) Miriam Votteler et al.   MACROMOLECULAR BIOSCIENCE

Subcellular-resolution delivery of a cytokine through precisely manipulated nanowires

(2010) Donglei Fan et al.   Nature Nanotechnology

Nanotechnological strategies for engineering complex tissues

(2010) Tal Dvir et al.   Nature Nanotechnology

Novel synthesis strategies for natural polymer and composite biomaterials as potential scaffolds for tissue engineering

(2010) H.-F. Ko et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY A-MATHEMATICAL PHYSICAL AND ENGINEERING SCIENCES

A Stem Cell-Based Tool for Small Molecule Screening in Adipogenesis

(2010) Jie Qin et al.   PLoS One

New Opportunities for an Ancient Material

(2010) F. G. Omenetto et al.   SCIENCE

Wnt Proteins Promote Bone Regeneration

(2010) S. Minear et al.   Science Translational Medicine

Cardiospheres Recapitulate a Niche-Like Microenvironment Rich in Stemness and Cell-Matrix Interactions, Rationalizing Their Enhanced Functional Potency for Myocardial Repair

(2010) Tao-Sheng Li et al.   STEM CELLS

Biocompatibility and drug delivery systems

(2010) Daniel S. Kohane et al.   Chemical Science

Injectable, rapid gelling and highly flexible hydrogel composites as growth factor and cell carriers

(2009) Feng Wang et al.   Acta Biomaterialia

Tunable Hydrogels for External Manipulation of Cellular Microenvironments through Controlled Photodegradation

(2009) April M. Kloxin et al.   ADVANCED MATERIALS

Cell-responsive hydrogel for encapsulation of vascular cells

(2009) Thomas P. Kraehenbuehl et al.   BIOMATERIALS

The influence of the sequential delivery of angiogenic factors from affinity-binding alginate scaffolds on vascularization

(2009) Inbar Freeman et al.   BIOMATERIALS

Effect of local sequential VEGF and BMP-2 delivery on ectopic and orthotopic bone regeneration

(2009) Diederik H.R. Kempen et al.   BIOMATERIALS

In situ elasticity modulation with dynamic substrates to direct cell phenotype

(2009) April M. Kloxin et al.   BIOMATERIALS

Adult cell therapy for brain neuronal damages and the role of tissue engineering

(2009) Gaëtan J.-R. Delcroix et al.   BIOMATERIALS

Anti-inflammatory peptide-functionalized hydrogels for insulin-secreting cell encapsulation

(2009) Jing Su et al.   BIOMATERIALS

Stimuli-responsive polymers and their applications in drug delivery

(2009) Priya Bawa et al.   Biomedical Materials

Development of an Ibuprofen-releasing biodegradable PLA/PGA electrospun scaffold for tissue regeneration

(2009) Irene Cantón et al.   BIOTECHNOLOGY AND BIOENGINEERING

Progenitors in motion: mechanisms of mobilization of endothelial progenitor cells

(2009) Lindsey Tilling et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Current approaches to stabilising and analysing proteins during microencapsulation in PLGA

(2009) Christopher F van der Walle et al.   Expert Opinion on Drug Delivery

Design and Implementation of Functional Nanoelectronic Interfaces With Biomolecules, Cells, and Tissue Using Nanowire Device Arrays

(2009) Brian P Timko et al.   IEEE TRANSACTIONS ON NANOTECHNOLOGY

Comparison of anti-tumor efficacy of paclitaxel delivered in nano- and microparticles

(2009) Sudhir S. Chakravarthi et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Preparation and characterization of protein-loaded polyanhydride microspheres

(2009) Lin Sun et al.   JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE

Synthesis of poly(propylene fumarate)

(2009) F Kurtis Kasper et al.   Nature Protocols

Nanoparticulate Systems for Growth Factor Delivery

(2009) Sufeng Zhang et al.   PHARMACEUTICAL RESEARCH

Prevascularization of cardiac patch on the omentum improves its therapeutic outcome

(2009) T. Dvir et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Functional muscle regeneration with combined delivery of angiogenesis and myogenesis factors

(2009) Cristina Borselli et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Photodegradable Hydrogels for Dynamic Tuning of Physical and Chemical Properties

(2009) April M. Kloxin et al.   SCIENCE

Encapsulation of Multiple Biological Compounds Within a Single Electrospun Fiber

(2009) Bin Dong et al.   Small

High-Throughput and Combinatorial Technologies for Tissue Engineering Applications

(2009) Anthony Peters et al.   TISSUE ENGINEERING PART B-REVIEWS

Vascular endothelial growth factor immobilized in collagen scaffold promotes penetration and proliferation of endothelial cells

(2008) Yi Hao Shen et al.   Acta Biomaterialia

Preparation and characterization of a novel bioactive restorative composite based on covalently coupled polyurethane–nanohydroxyapatite fibres

(2008) A.S. Khan et al.   Acta Biomaterialia

Structural Modification of Protease Inducible Preprogrammed Nanofiber Precursor

(2008) Benedict Law et al.   BIOMACROMOLECULES

Enhancement of poly(orthoester) microspheres for DNA vaccine delivery by blending with poly(ethylenimine)

(2008) David N. Nguyen et al.   BIOMATERIALS

The effect of sulfation of alginate hydrogels on the specific binding and controlled release of heparin-binding proteins

(2008) Inbar Freeman et al.   BIOMATERIALS

Three-dimensional extracellular matrix-directed cardioprogenitor differentiation: Systematic modulation of a synthetic cell-responsive PEG-hydrogel

(2008) Thomas P. Kraehenbuehl et al.   BIOMATERIALS

Incorporation of a matrix metalloproteinase-sensitive substrate into self-assembling peptides – A model for biofunctional scaffolds

(2008) Ying Chau et al.   BIOMATERIALS

Electrospinning: Applications in drug delivery and tissue engineering

(2008) Travis J. Sill et al.   BIOMATERIALS

Poly(lactic-co-glycolic acid) nanospheres and microspheres for short- and long-term delivery of bioactive ciliary neurotrophic factor

(2008) Michael K. Nkansah et al.   BIOTECHNOLOGY AND BIOENGINEERING

Degradation and Healing Characteristics of Small-Diameter Poly(ε-Caprolactone) Vascular Grafts in the Rat Systemic Arterial Circulation

(2008) Erman Pektok et al.   CIRCULATION

Wnt signaling controls the fate of mesenchymal stem cells

(2008) Ling Ling et al.   GENE

Principles of encapsulating hydrophobic drugs in PLA/PLGA microparticles

(2008) Christian Wischke et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Erythropoietin-mediated tissue protection: reducing collateral damage from the primary injury response

(2008) M. Brines et al.   JOURNAL OF INTERNAL MEDICINE

Recruitment of Endogenous Stem Cells for Tissue Repair

(2008) Jing Zhao et al.   MACROMOLECULAR BIOSCIENCE

A chemical approach to stem-cell biology and regenerative medicine

(2008) Yue Xu et al.   NATURE

Small functional groups for controlled differentiation of hydrogel-encapsulated human mesenchymal stem cells

(2008) Danielle S. W. Benoit et al.   NATURE MATERIALS

Drug-sensing hydrogels for the inducible release of biopharmaceuticals

(2008) Martin Ehrbar et al.   NATURE MATERIALS

Functional immobilization of signaling proteins enables control of stem cell fate

(2008) Kristin Alberti et al.   NATURE METHODS

Polymeric Biomaterials in Tissue Engineering

(2008) Daniel S Kohane et al.   PEDIATRIC RESEARCH

Induction of angiogenesis in tissue-engineered scaffolds designed for bone repair: A combined gene therapy-cell transplantation approach

(2008) E. Jabbarzadeh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Fibroblast Growth Factor-2 and -4 Promote the Proliferation of Bone Marrow Mesenchymal Stem Cells by the Activation of the PI3K-Akt and ERK1/2 Signaling Pathways

(2008) Seung-Cheol Choi et al.   STEM CELLS AND DEVELOPMENT

Delivery of Basic Fibroblast Growth Factor from Gelatin Microsphere Scaffold for the Growth of Human Umbilical Vein Endothelial Cells

(2008) Xin Hao Zhu et al.   TISSUE ENGINEERING PART A

Insulin-like Growth Factor-I and Slow, Bi-directional Perfusion Enhance the Formation of Tissue-Engineered Cardiac Grafts

(2008) Mingyu Cheng et al.   TISSUE ENGINEERING PART A

Microsphere-Based Seamless Scaffolds Containing Macroscopic Gradients of Encapsulated Factors for Tissue Engineering

(2008) Milind Singh et al.   TISSUE ENGINEERING PART C-METHODS

Controlled differentiation of stem cells

(2007) Nathaniel S. Hwang et al.   ADVANCED DRUG DELIVERY REVIEWS

Chemical Degradation of Peptides and Proteins in PLGA: A Review of Reactions and Mechanisms

(2007) M.L. Houchin et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Delivering growth factors for therapeutics

(2007) Eduardo Anitua et al.   TRENDS IN PHARMACOLOGICAL SCIENCES